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Found 3 of ic50 for UniProtKB: Q9ULW0
TargetAurora kinase A/Targeting protein for Xklp2(Homo sapiens (Human))
Nirma University

Curated by ChEMBL
LigandPNGBDBM209861(5-(3-ethylsulfonylphenyl)-3,8-dimethyl-N-(1-methyl...)
Affinity DataIC50:  21nMAssay Description:Inhibition of Aurora A/TPX2 (unknown origin) pre-incubated for 1 hr followed by FL-Kemptide substrate and ATP additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A/Targeting protein for Xklp2 [1-43](Homo sapiens (Human))
University of Tartu

LigandPNGBDBM50277545(4-(9-chloro-7-(2-fluoro-6-methoxyphenyl)-5H-benzo[...)
Affinity DataKi:  1.86nM ΔG°:  -12.1kcal/mole IC50:  1.78E+3nMT: 2°CAssay Description:Threefold dilution series of inhibitors in assay buffer were prepared in wells of a microtiter plate (final concentration stating from 2uM), and TAMR...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A/Targeting protein for Xklp2 [1-43](Homo sapiens (Human))
University of Tartu

LigandPNGBDBM109209(VX-689)
Affinity DataKi:  2.17nM ΔG°:  -12.0kcal/mole IC50:  2.07E+3nMT: 2°CAssay Description:Threefold dilution series of inhibitors in assay buffer were prepared in wells of a microtiter plate (final concentration stating from 2uM), and TAMR...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed