Affinity DataKi: 22nMAssay Description:Reversible inhibition of CYP2C8 in human liver microsomes after 5 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
Affinity DataKi: 52nMAssay Description:Time dependent inhibition of CYP2C8 in human liver microsomes after 5 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
Affinity DataKi: 1.10E+3nMAssay Description:Competitive inhibition of CYP2C8 in human liver microsomes assessed as paclitaxel 6-hydroxylation after 20 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
Affinity DataKi: 1.20E+3nMAssay Description:Mechanism based inhibition of human cytochrome P450 2C8 measured by paclitaxel hydroxylation using a recombinant systemMore data for this Ligand-Target Pair
Affinity DataKi: 1.50E+3nMAssay Description:Mechanism based inhibition of human cytochrome P450 2C8 measured by paclitaxel hydroxylation using a recombinant systemMore data for this Ligand-Target Pair
Affinity DataKi: 1.80E+3nMAssay Description:Biphasic inhibition of CYP2C8 in human liver microsomes assessed as montelukast 36-hydroxylation after 20 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
Affinity DataKi: 2.70E+3nMAssay Description:Linear mixed inhibition of CYP2C8 in human liver microsomes assessed as paclitaxel 6-hydroxylation after 20 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
Affinity DataKi: 6.00E+3nMAssay Description:Competitive inhibition of CYP2C8 in human liver microsomes assessed as rosiglitazone demethylation after 20 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
Affinity DataKi: 6.90E+3nMAssay Description:Linear mixed inhibition of CYP2C8 in human liver microsomes assessed as rosiglitazone demethylation after 20 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
Affinity DataKi: 7.30E+3nMAssay Description:Biphasic inhibition of CYP2C8 in human liver microsomes assessed as montelukast 36-hydroxylation after 20 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
Affinity DataKi: 9.90E+3nMAssay Description:Inhibition of CYP2C8 in human liver microsomes preincubated for 30 mins followed by substrate addition measured after 2 minsMore data for this Ligand-Target Pair
Affinity DataKi: 1.10E+4nMAssay Description:Inhibition of recombinant human CYP2C8 expressed in microsomes isolated from baculovirus infected insect cell after 3 minsMore data for this Ligand-Target Pair
Affinity DataKi: 1.75E+4nMAssay Description:Mechanism based inhibition of human cytochrome P450 2C8 measured by paclitaxel hydroxylation using a recombinant systemMore data for this Ligand-Target Pair
Affinity DataKi: 2.00E+4nMAssay Description:Inhibition of CYP2C8 in human liver microsomes using paclitaxel as substrate preincubated for 2 to 40 mins measured after 2 minsMore data for this Ligand-Target Pair
Affinity DataKi: 2.00E+4nMAssay Description:Time dependent inhibition of CYP2C8 in human liver microsomesMore data for this Ligand-Target Pair
Affinity DataKi: 3.17E+4nMAssay Description:Inhibition of recombinant CYP2C8 (unknown origin) treated with AMG 853More data for this Ligand-Target Pair
Affinity DataKi: 4.99E+4nMAssay Description:Mechanism based inhibition of human cytochrome P450 2C8 measured by paclitaxel hydroxylation using a recombinant systemMore data for this Ligand-Target Pair
Affinity DataKi: 5.12E+4nMAssay Description:Mechanism based inhibition of human cytochrome P450 2C8 measured by paclitaxel hydroxylation using human liver microsomesMore data for this Ligand-Target Pair
Affinity DataKi: 5.20E+4nMAssay Description:Inhibition of CYP2C8 in human liver microsomes using paclitaxel as substrate preincubated for 2 to 40 mins followed by NADPH-generating system additi...More data for this Ligand-Target Pair
Affinity DataKi: 5.43E+4nMAssay Description:Mechanism based inhibition of human cytochrome P450 2C8 measured by paclitaxel hydroxylation using human liver microsomesMore data for this Ligand-Target Pair
Affinity DataKi: 1.70E+5nMAssay Description:Mechanism based inhibition of human cytochrome P450 2C8 measured by paclitaxel hydroxylation using human liver microsomesMore data for this Ligand-Target Pair
Affinity DataKi: 2.94E+5nMAssay Description:Mechanism based inhibition of human cytochrome P450 2C8 measured by paclitaxel hydroxylation using a recombinant systemMore data for this Ligand-Target Pair
Affinity DataKi: 3.74E+5nMAssay Description:Mechanism based inhibition of human cytochrome P450 2C8 measured by paclitaxel hydroxylation using a recombinant systemMore data for this Ligand-Target Pair
