Compile Data Set for Download or QSAR
maximum 50k data
Found 28 of ki for UniProtKB: Q8TCW9
TargetProkineticin receptor 1(Homo sapiens (Human))
The Regents of The University of California

US Patent
LigandPNGBDBM463303((-)-(2R)-1-(2-Methoxybenzyl)- N-(9-chloro-3,4-dihy...)
Affinity DataKi:  1.49nMAssay Description:An aequorin-based luminescent assay for calcium mobilization was used to measure mobilization of intracellular Ca2+ (Bullock et al., Mol Pharmacol 65...More data for this Ligand-Target Pair
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TargetProkineticin receptor 1(Homo sapiens (Human))
The Regents of The University of California

US Patent
LigandPNGBDBM463304((-)-(2R)-1-(3-Methoxybenzyl)- N-(9-chloro-3,4-dihy...)
Affinity DataKi:  2.5nMAssay Description:An aequorin-based luminescent assay for calcium mobilization was used to measure mobilization of intracellular Ca2+ (Bullock et al., Mol Pharmacol 65...More data for this Ligand-Target Pair
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TargetProkineticin receptor 1(Homo sapiens (Human))
The Regents of The University of California

US Patent
LigandPNGBDBM463306((-)-(2R)-1-(4-Fluoro-3- methoxybenzyl)-N-(9-chloro...)
Affinity DataKi:  2.60nMAssay Description:An aequorin-based luminescent assay for calcium mobilization was used to measure mobilization of intracellular Ca2+ (Bullock et al., Mol Pharmacol 65...More data for this Ligand-Target Pair
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TargetProkineticin receptor 1(Homo sapiens (Human))
The Regents of The University of California

US Patent
LigandPNGBDBM463307((-)-(3R)-1-(benzimidazol-4- ylmethyl)-N-(9-chloro-...)
Affinity DataKi:  2.60nMAssay Description:An aequorin-based luminescent assay for calcium mobilization was used to measure mobilization of intracellular Ca2+ (Bullock et al., Mol Pharmacol 65...More data for this Ligand-Target Pair
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TargetProkineticin receptor 1(Homo sapiens (Human))
The Regents of The University of California

US Patent
LigandPNGBDBM463308((-)-(2R)-2-Methyl-3- (benzimidazol-4- ylmethylamin...)
Affinity DataKi:  3.5nMAssay Description:An aequorin-based luminescent assay for calcium mobilization was used to measure mobilization of intracellular Ca2+ (Bullock et al., Mol Pharmacol 65...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetProkineticin receptor 1(Homo sapiens (Human))
The Regents of The University of California

US Patent
LigandPNGBDBM463321((-)-(2R)-1-(4,6-Difluoro-3- methoxybenzyl)-N-(9-ch...)
Affinity DataKi:  4.09nMAssay Description:An aequorin-based luminescent assay for calcium mobilization was used to measure mobilization of intracellular Ca2+ (Bullock et al., Mol Pharmacol 65...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetProkineticin receptor 1(Homo sapiens (Human))
The Regents of The University of California

US Patent
LigandPNGBDBM463326((+-)-2-Methyl-3-((3-hydroxy-4- fluoro)benzylamino)...)
Affinity DataKi:  4.40nMAssay Description:An aequorin-based luminescent assay for calcium mobilization was used to measure mobilization of intracellular Ca2+ (Bullock et al., Mol Pharmacol 65...More data for this Ligand-Target Pair
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TargetProkineticin receptor 1(Homo sapiens (Human))
The Regents of The University of California

US Patent
LigandPNGBDBM463309((+-)-2-Methyl-3-(benzimidazol- 4-ylmethylamino)-N-...)
Affinity DataKi:  5.60nMAssay Description:An aequorin-based luminescent assay for calcium mobilization was used to measure mobilization of intracellular Ca2+ (Bullock et al., Mol Pharmacol 65...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetProkineticin receptor 1(Homo sapiens (Human))
The Regents of The University of California

US Patent
LigandPNGBDBM463313((-)-(2R)-1-(5-fluro- benzimidazol-4-ylmethyl)-N- (...)
Affinity DataKi:  6.14nMAssay Description:An aequorin-based luminescent assay for calcium mobilization was used to measure mobilization of intracellular Ca2+ (Bullock et al., Mol Pharmacol 65...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetProkineticin receptor 1(Homo sapiens (Human))
The Regents of The University of California

US Patent
LigandPNGBDBM463316((-)-(3R)-1-(4,6-Difluoro-3- methoxybenzyl)-N-(9-ch...)
Affinity DataKi:  6.14nMAssay Description:An aequorin-based luminescent assay for calcium mobilization was used to measure mobilization of intracellular Ca2+ (Bullock et al., Mol Pharmacol 65...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetProkineticin receptor 1(Homo sapiens (Human))
The Regents of The University of California

US Patent
LigandPNGBDBM463305((-)-(2R)-1-(4-Fluoro-2- methoxybenzyl)-N-(9-chloro...)
Affinity DataKi:  7.30nMAssay Description:An aequorin-based luminescent assay for calcium mobilization was used to measure mobilization of intracellular Ca2+ (Bullock et al., Mol Pharmacol 65...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetProkineticin receptor 1(Homo sapiens (Human))
The Regents of The University of California

US Patent
LigandPNGBDBM463325((-)-(2R)-1-(5-Fluoro-2- methoxybenzyl)-N-(9-chloro...)
Affinity DataKi:  7.30nMAssay Description:An aequorin-based luminescent assay for calcium mobilization was used to measure mobilization of intracellular Ca2+ (Bullock et al., Mol Pharmacol 65...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProkineticin receptor 1(Homo sapiens (Human))
The Regents of The University of California

US Patent
LigandPNGBDBM463312((-)-(2R)-1-(benzimidazol-4- ylmethyl)-N-(9-chloro-...)
Affinity DataKi:  8.40nMAssay Description:An aequorin-based luminescent assay for calcium mobilization was used to measure mobilization of intracellular Ca2+ (Bullock et al., Mol Pharmacol 65...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProkineticin receptor 1(Homo sapiens (Human))
The Regents of The University of California

US Patent
LigandPNGBDBM463319((-)-(3R)-1-(5-Fluoro-2- methoxybenzyl)-N-(9-chloro...)
Affinity DataKi:  9.30nMAssay Description:An aequorin-based luminescent assay for calcium mobilization was used to measure mobilization of intracellular Ca2+ (Bullock et al., Mol Pharmacol 65...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProkineticin receptor 1(Homo sapiens (Human))
The Regents of The University of California

US Patent
LigandPNGBDBM463315((-)-(3R)-1-(4-Fluoro-2- methoxybenzyl)-N-(9-chloro...)
Affinity DataKi:  9.32nMAssay Description:An aequorin-based luminescent assay for calcium mobilization was used to measure mobilization of intracellular Ca2+ (Bullock et al., Mol Pharmacol 65...More data for this Ligand-Target Pair
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TargetProkineticin receptor 1(Homo sapiens (Human))
The Regents of The University of California

US Patent
LigandPNGBDBM463324((-)-(2R)-1-(6-Fluoro-3- methoxybenzyl)-N-(9-chloro...)
Affinity DataKi:  10nMAssay Description:An aequorin-based luminescent assay for calcium mobilization was used to measure mobilization of intracellular Ca2+ (Bullock et al., Mol Pharmacol 65...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProkineticin receptor 1(Homo sapiens (Human))
The Regents of The University of California

US Patent
LigandPNGBDBM463323((-)-(3R)-1-(4,6-Difluoro-3- methoxybenzyl)-N-(9-ch...)
Affinity DataKi:  13.8nMAssay Description:An aequorin-based luminescent assay for calcium mobilization was used to measure mobilization of intracellular Ca2+ (Bullock et al., Mol Pharmacol 65...More data for this Ligand-Target Pair
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TargetProkineticin receptor 1(Homo sapiens (Human))
The Regents of The University of California

US Patent
LigandPNGBDBM26335(3-[2-({5-[(4-ethylphenyl)methyl]-1-[(4-methoxyphen...)
Affinity DataKi:  22nM ΔG°:  -10.9kcal/molepH: 7.4 T: 2°CAssay Description:Nonspecific binding was determined in the presence of 1 uM Bv8. Displacement curves were determined in triplicate. The inhibition constant (Ki) of th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProkineticin receptor 1(Homo sapiens (Human))
The Regents of The University of California

US Patent
LigandPNGBDBM463320((-)-(3R)-1-(5-Fluoro-3- methoxybenzyl)-N-(9-chloro...)
Affinity DataKi:  41.5nMAssay Description:An aequorin-based luminescent assay for calcium mobilization was used to measure mobilization of intracellular Ca2+ (Bullock et al., Mol Pharmacol 65...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetProkineticin receptor 1(Homo sapiens (Human))
The Regents of The University of California

US Patent
LigandPNGBDBM463322((+-)-2-Methyl-3-((3-methoxy- 4,6-difluoro)benzylam...)
Affinity DataKi:  43.5nMAssay Description:An aequorin-based luminescent assay for calcium mobilization was used to measure mobilization of intracellular Ca2+ (Bullock et al., Mol Pharmacol 65...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetProkineticin receptor 1(Homo sapiens (Human))
The Regents of The University of California

US Patent
LigandPNGBDBM463310((-)-(3R)-1-(5-fluro- benzimidazol-4-ylmethyl)-N- (...)
Affinity DataKi:  71.3nMAssay Description:An aequorin-based luminescent assay for calcium mobilization was used to measure mobilization of intracellular Ca2+ (Bullock et al., Mol Pharmacol 65...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProkineticin receptor 1(Homo sapiens (Human))
The Regents of The University of California

US Patent
LigandPNGBDBM463311((-)-(3R)-1-(benzimidazol-4- ylmethyl)-N-(9-chloro-...)
Affinity DataKi:  97nMAssay Description:An aequorin-based luminescent assay for calcium mobilization was used to measure mobilization of intracellular Ca2+ (Bullock et al., Mol Pharmacol 65...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetProkineticin receptor 1(Homo sapiens (Human))
The Regents of The University of California

US Patent
LigandPNGBDBM463327((-)-(3R)-1-(4-Fluoro-3- hydroxybenzyl)-N-(9-chloro...)
Affinity DataKi:  107nMAssay Description:An aequorin-based luminescent assay for calcium mobilization was used to measure mobilization of intracellular Ca2+ (Bullock et al., Mol Pharmacol 65...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProkineticin receptor 1(Homo sapiens (Human))
The Regents of The University of California

US Patent
LigandPNGBDBM463314((-)-(3R)-1-(3-Fluoro-2- methoxybenzyl)-N-(9-chloro...)
Affinity DataKi:  170nMAssay Description:An aequorin-based luminescent assay for calcium mobilization was used to measure mobilization of intracellular Ca2+ (Bullock et al., Mol Pharmacol 65...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProkineticin receptor 1(Homo sapiens (Human))
The Regents of The University of California

US Patent
LigandPNGBDBM463317((-)-(3R)-1-(6-Fluoro-3- methoxybenzyl)-N-(9-chloro...)
Affinity DataKi:  301nMAssay Description:An aequorin-based luminescent assay for calcium mobilization was used to measure mobilization of intracellular Ca2+ (Bullock et al., Mol Pharmacol 65...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetProkineticin receptor 1(Homo sapiens (Human))
The Regents of The University of California

US Patent
LigandPNGBDBM463318((-)-(3R)-1-(5-Fluoro-3- methoxybenzyl)-N-(9-chloro...)
Affinity DataKi:  373nMAssay Description:An aequorin-based luminescent assay for calcium mobilization was used to measure mobilization of intracellular Ca2+ (Bullock et al., Mol Pharmacol 65...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetProkineticin receptor 1(Homo sapiens (Human))
The Regents of The University of California

US Patent
LigandPNGBDBM26336(6-[(2-aminoethyl)amino]-3-[(4-ethylphenyl)methyl]-...)
Affinity DataKi:  440nM ΔG°:  -9.01kcal/molepH: 7.4 T: 2°CAssay Description:Nonspecific binding was determined in the presence of 1 uM Bv8. Displacement curves were determined in triplicate. The inhibition constant (Ki) of th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProkineticin receptor 1(Homo sapiens (Human))
The Regents of The University of California

US Patent
LigandPNGBDBM26337(6-{[2-(4,5-dihydro-1H-imidazol-2-ylamino)ethyl]ami...)
Affinity DataKi:  4.72E+3nM ΔG°:  -7.55kcal/molepH: 7.4 T: 2°CAssay Description:Nonspecific binding was determined in the presence of 1 uM Bv8. Displacement curves were determined in triplicate. The inhibition constant (Ki) of th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed