TargetWD repeat-containing protein 5(Homo sapiens (Human))
Ontario Institute For Cancer Research
Curated by ChEMBL
Ontario Institute For Cancer Research
Curated by ChEMBL
Affinity DataIC50: 0.900nMAssay Description:Inhibition of SUMO-His-tagged WDR5 (unknown origin) interaction with MLL1 assessed as displacement of fluorescence labelled Ac-ARA peptide substrate ...More data for this Ligand-Target Pair
TargetWD repeat-containing protein 5(Homo sapiens (Human))
Ontario Institute For Cancer Research
Curated by ChEMBL
Ontario Institute For Cancer Research
Curated by ChEMBL
Affinity DataIC50: 0.900nMAssay Description:Binding affinity to WDR5 (unknown origin) fluorescence polarization assayMore data for this Ligand-Target Pair
TargetWD repeat-containing protein 5(Homo sapiens (Human))
Ontario Institute For Cancer Research
Curated by ChEMBL
Ontario Institute For Cancer Research
Curated by ChEMBL
Affinity DataIC50: 0.900nMAssay Description:Displacement of fluorescence-labelled Ac-ARA peptide from WDR5 (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetWD repeat-containing protein 5(Homo sapiens (Human))
Ontario Institute For Cancer Research
Curated by ChEMBL
Ontario Institute For Cancer Research
Curated by ChEMBL
Affinity DataIC50: 0.900nMAssay Description:Inhibition of fluorescence-labeled Ac-ARA peptide binding to WDR5 (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetWD repeat-containing protein 5(Homo sapiens (Human))
Ontario Institute For Cancer Research
Curated by ChEMBL
Ontario Institute For Cancer Research
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Binding affinity to WDR5 expressed in pLysS cells after 24 hrs by optimized fluorescent polarization based saturation binding assayMore data for this Ligand-Target Pair
TargetWD repeat-containing protein 5(Homo sapiens (Human))
Ontario Institute For Cancer Research
Curated by ChEMBL
Ontario Institute For Cancer Research
Curated by ChEMBL
Affinity DataIC50: 1.70nMAssay Description:Inhibition of 10mer-Thr-FAM probe binding to human WDR5 after 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetWD repeat-containing protein 5(Homo sapiens (Human))
Ontario Institute For Cancer Research
Curated by ChEMBL
Ontario Institute For Cancer Research
Curated by ChEMBL
Affinity DataIC50: 2.40nMAssay Description:Displacement of fluorescence-labelled Ac-ARA peptide from WDR5 (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetWD repeat-containing protein 5(Homo sapiens (Human))
Ontario Institute For Cancer Research
Curated by ChEMBL
Ontario Institute For Cancer Research
Curated by ChEMBL
Affinity DataIC50: 2.40nMAssay Description:Inhibition of WDR5 (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetWD repeat-containing protein 5(Homo sapiens (Human))
Ontario Institute For Cancer Research
Curated by ChEMBL
Ontario Institute For Cancer Research
Curated by ChEMBL
Affinity DataIC50: 2.40nMAssay Description:Inhibition of C-terminal 5-FAM-WIN peptide binding to N-terminal His-tagged WDR5 (24 to 334 residues) (unknown origin) expressed in Rosetta2-(DE3) pL...More data for this Ligand-Target Pair
TargetWD repeat-containing protein 5(Homo sapiens (Human))
Ontario Institute For Cancer Research
Curated by ChEMBL
Ontario Institute For Cancer Research
Curated by ChEMBL
Affinity DataIC50: 2.40nMAssay Description:Binding affinity to WDR5 (unknown origin) fluorescence polarization assayMore data for this Ligand-Target Pair
TargetWD repeat-containing protein 5(Homo sapiens (Human))
Ontario Institute For Cancer Research
Curated by ChEMBL
Ontario Institute For Cancer Research
Curated by ChEMBL
Affinity DataIC50: 2.40nMAssay Description:Inhibition of fluorescence-labeled Ac-ARA peptide binding to WDR5 (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.60nMAssay Description:WDR5 TR-FRET Assay Procedure: Stock compounds were transferred to the assay plate by Echo Liquid Handler. Reactions were performed in the assay buffe...More data for this Ligand-Target Pair
TargetWD repeat-containing protein 5(Homo sapiens (Human))
Ontario Institute For Cancer Research
Curated by ChEMBL
Ontario Institute For Cancer Research
Curated by ChEMBL
Affinity DataIC50: 2.90nMAssay Description:Displacement of fluorescence-labelled Ac-ARA peptide from WDR5 (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetWD repeat-containing protein 5(Homo sapiens (Human))
Ontario Institute For Cancer Research
Curated by ChEMBL
Ontario Institute For Cancer Research
Curated by ChEMBL
Affinity DataIC50: 2.90nMAssay Description:Inhibition of N-terminal His-tagged WDR5 (24 to 334 residues) (unknown origin) interaction with MLL1 assessed as displacement of 5-Lys-FAM peptide su...More data for this Ligand-Target Pair
TargetWD repeat-containing protein 5(Homo sapiens (Human))
Ontario Institute For Cancer Research
Curated by ChEMBL
Ontario Institute For Cancer Research
Curated by ChEMBL
Affinity DataIC50: 2.90nMAssay Description:Binding affinity to WDR5 (unknown origin) fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:WDR5 TR-FRET Assay Procedure: Stock compounds were transferred to the assay plate by Echo Liquid Handler. Reactions were performed in the assay buffe...More data for this Ligand-Target Pair
Affinity DataIC50: 3.08nMAssay Description:WDR5 TR-FRET Assay Procedure: Stock compounds were transferred to the assay plate by Echo Liquid Handler. Reactions were performed in the assay buffe...More data for this Ligand-Target Pair
Affinity DataIC50: 3.65nMAssay Description:WDR5 TR-FRET Assay Procedure: Stock compounds were transferred to the assay plate by Echo Liquid Handler. Reactions were performed in the assay buffe...More data for this Ligand-Target Pair
Affinity DataIC50: 3.86nMAssay Description:WDR5 TR-FRET Assay Procedure: Stock compounds were transferred to the assay plate by Echo Liquid Handler. Reactions were performed in the assay buffe...More data for this Ligand-Target Pair
Affinity DataIC50: 3.99nMAssay Description:WDR5 TR-FRET Assay Procedure: Stock compounds were transferred to the assay plate by Echo Liquid Handler. Reactions were performed in the assay buffe...More data for this Ligand-Target Pair
TargetWD repeat-containing protein 5(Homo sapiens (Human))
Ontario Institute For Cancer Research
Curated by ChEMBL
Ontario Institute For Cancer Research
Curated by ChEMBL
Affinity DataIC50: 4.5nMAssay Description:Displacement of fluorescence-labelled Ac-ARA peptide from WDR5 (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4.72nMAssay Description:WDR5 TR-FRET Assay Procedure: Stock compounds were transferred to the assay plate by Echo Liquid Handler. Reactions were performed in the assay buffe...More data for this Ligand-Target Pair
Affinity DataIC50: 4.91nMAssay Description:WDR5 TR-FRET Assay Procedure: Stock compounds were transferred to the assay plate by Echo Liquid Handler. Reactions were performed in the assay buffe...More data for this Ligand-Target Pair
Affinity DataIC50: 5.24nMAssay Description:WDR5 TR-FRET Assay Procedure: Stock compounds were transferred to the assay plate by Echo Liquid Handler. Reactions were performed in the assay buffe...More data for this Ligand-Target Pair
TargetWD repeat-containing protein 5(Homo sapiens (Human))
Ontario Institute For Cancer Research
Curated by ChEMBL
Ontario Institute For Cancer Research
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Binding affinity to WDR5 expressed in pLysS cells by optimized fluorescent polarization based competitive binding assayMore data for this Ligand-Target Pair
TargetWD repeat-containing protein 5(Homo sapiens (Human))
Ontario Institute For Cancer Research
Curated by ChEMBL
Ontario Institute For Cancer Research
Curated by ChEMBL
Affinity DataIC50: 6.5nMAssay Description:Displacement of 10mer-Thr-FAM probe from WDR5 (unknown origin) incubated for 30 mins by fluorescence polarizaton assayMore data for this Ligand-Target Pair
Affinity DataIC50: 7.09nMAssay Description:WDR5 TR-FRET Assay Procedure: Stock compounds were transferred to the assay plate by Echo Liquid Handler. Reactions were performed in the assay buffe...More data for this Ligand-Target Pair
Affinity DataIC50: 7.23nMAssay Description:WDR5 TR-FRET Assay Procedure: Stock compounds were transferred to the assay plate by Echo Liquid Handler. Reactions were performed in the assay buffe...More data for this Ligand-Target Pair
TargetWD repeat-containing protein 5(Homo sapiens (Human))
Ontario Institute For Cancer Research
Curated by ChEMBL
Ontario Institute For Cancer Research
Curated by ChEMBL
Affinity DataIC50: 7.40nMAssay Description:Binding affinity to WDR5 (unknown origin) fluorescence polarization assayMore data for this Ligand-Target Pair
TargetWD repeat-containing protein 5(Homo sapiens (Human))
Ontario Institute For Cancer Research
Curated by ChEMBL
Ontario Institute For Cancer Research
Curated by ChEMBL
Affinity DataIC50: 7.60nMAssay Description:Inhibition of 10mer-Thr-FAM probe binding to human WDR5 after 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetWD repeat-containing protein 5(Homo sapiens (Human))
Ontario Institute For Cancer Research
Curated by ChEMBL
Ontario Institute For Cancer Research
Curated by ChEMBL
Affinity DataIC50: 7.60nMAssay Description:Displacement of 10mer-Thr-FAM probe from WDR5 (unknown origin) incubated for 30 mins by fluorescence polarizaton assayMore data for this Ligand-Target Pair
Affinity DataIC50: 8.23nMAssay Description:WDR5 TR-FRET Assay Procedure: Stock compounds were transferred to the assay plate by Echo Liquid Handler. Reactions were performed in the assay buffe...More data for this Ligand-Target Pair
TargetWD repeat-containing protein 5(Homo sapiens (Human))
Ontario Institute For Cancer Research
Curated by ChEMBL
Ontario Institute For Cancer Research
Curated by ChEMBL
Affinity DataIC50: 8.5nMAssay Description:Inhibition of 10mer-Thr-FAM probe binding to human WDR5 after 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetWD repeat-containing protein 5(Homo sapiens (Human))
Ontario Institute For Cancer Research
Curated by ChEMBL
Ontario Institute For Cancer Research
Curated by ChEMBL
Affinity DataIC50: 8.60nMAssay Description:Displacement of 10mer-Thr-FAM probe from WDR5 (unknown origin) incubated for 30 mins by fluorescence polarizaton assayMore data for this Ligand-Target Pair
TargetWD repeat-containing protein 5(Homo sapiens (Human))
Ontario Institute For Cancer Research
Curated by ChEMBL
Ontario Institute For Cancer Research
Curated by ChEMBL
Affinity DataIC50: 8.90nMAssay Description:Displacement of 10mer-Thr-FAM probe from WDR5 (unknown origin) incubated for 30 mins by fluorescence polarizaton assayMore data for this Ligand-Target Pair
TargetWD repeat-containing protein 5(Homo sapiens (Human))
Ontario Institute For Cancer Research
Curated by ChEMBL
Ontario Institute For Cancer Research
Curated by ChEMBL
Affinity DataIC50: 9nMAssay Description:Displacement of 10mer-Thr-FAM probe from WDR5 (unknown origin) incubated for 30 mins by fluorescence polarizaton assayMore data for this Ligand-Target Pair
Affinity DataIC50: 9.12nMAssay Description:WDR5 TR-FRET Assay Procedure: Stock compounds were transferred to the assay plate by Echo Liquid Handler. Reactions were performed in the assay buffe...More data for this Ligand-Target Pair
Affinity DataIC50: 9.62nMAssay Description:WDR5 TR-FRET Assay Procedure: Stock compounds were transferred to the assay plate by Echo Liquid Handler. Reactions were performed in the assay buffe...More data for this Ligand-Target Pair
TargetWD repeat-containing protein 5(Homo sapiens (Human))
Ontario Institute For Cancer Research
Curated by ChEMBL
Ontario Institute For Cancer Research
Curated by ChEMBL
Affinity DataIC50: <10nMAssay Description:Binding affinity to WDR5 (unknown origin) fluorescence polarization assayMore data for this Ligand-Target Pair
TargetWD repeat-containing protein 5(Homo sapiens (Human))
Ontario Institute For Cancer Research
Curated by ChEMBL
Ontario Institute For Cancer Research
Curated by ChEMBL
Affinity DataIC50: <10nMAssay Description:Binding affinity to WDR5 (unknown origin) using 10mer-Thr-FAM as substrate incubated for 30 mins by fluorescence polarization based competitive bindi...More data for this Ligand-Target Pair
Affinity DataIC50: 10.8nMAssay Description:WDR5 TR-FRET Assay Procedure: Stock compounds were transferred to the assay plate by Echo Liquid Handler. Reactions were performed in the assay buffe...More data for this Ligand-Target Pair
TargetWD repeat-containing protein 5(Homo sapiens (Human))
Ontario Institute For Cancer Research
Curated by ChEMBL
Ontario Institute For Cancer Research
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Displacement of 10mer-Thr-FAM probe from WDR5 (unknown origin) incubated for 30 mins by fluorescence polarizaton assayMore data for this Ligand-Target Pair
TargetWD repeat-containing protein 5(Homo sapiens (Human))
Ontario Institute For Cancer Research
Curated by ChEMBL
Ontario Institute For Cancer Research
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Binding affinity to WDR5 expressed in pLysS cells after 24 hrs by optimized fluorescent polarization based saturation binding assayMore data for this Ligand-Target Pair
TargetWD repeat-containing protein 5(Homo sapiens (Human))
Ontario Institute For Cancer Research
Curated by ChEMBL
Ontario Institute For Cancer Research
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Inhibition of 10mer-Thr-FAM probe binding to human WDR5 after 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 15.6nMAssay Description:WDR5 TR-FRET Assay Procedure: Stock compounds were transferred to the assay plate by Echo Liquid Handler. Reactions were performed in the assay buffe...More data for this Ligand-Target Pair
TargetWD repeat-containing protein 5(Homo sapiens (Human))
Ontario Institute For Cancer Research
Curated by ChEMBL
Ontario Institute For Cancer Research
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Displacement of 10mer-Thr-FAM probe from WDR5 (unknown origin) incubated for 30 mins by fluorescence polarizaton assayMore data for this Ligand-Target Pair
TargetWD repeat-containing protein 5(Homo sapiens (Human))
Ontario Institute For Cancer Research
Curated by ChEMBL
Ontario Institute For Cancer Research
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Displacement of 10mer-Thr-FAM probe from WDR5 (unknown origin) incubated for 30 mins by fluorescence polarizaton assayMore data for this Ligand-Target Pair
Affinity DataIC50: 16.6nMAssay Description:WDR5 TR-FRET Assay Procedure: Stock compounds were transferred to the assay plate by Echo Liquid Handler. Reactions were performed in the assay buffe...More data for this Ligand-Target Pair
Affinity DataIC50: 16.8nMAssay Description:WDR5 TR-FRET Assay Procedure: Stock compounds were transferred to the assay plate by Echo Liquid Handler. Reactions were performed in the assay buffe...More data for this Ligand-Target Pair
TargetWD repeat-containing protein 5(Homo sapiens (Human))
Ontario Institute For Cancer Research
Curated by ChEMBL
Ontario Institute For Cancer Research
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:Binding affinity to WDR5 (unknown origin) WIN site using 10mer-Thr-FAM probe incubated for 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
