TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Rattus norvegicus (Rat))
The University Of Queensland
Curated by ChEMBL
The University Of Queensland
Curated by ChEMBL
Affinity DataIC50: 0.170nMAssay Description:Inhibition of rat Nicotinic acetylcholine receptor alpha3-beta2 expressed in Xenopus OocytesMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Rattus norvegicus (Rat))
The University Of Queensland
Curated by ChEMBL
The University Of Queensland
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Inhibition of rat Nicotinic acetylcholine receptor alpha3-beta2 expressed in Xenopus OocytesMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Affinity DataIC50: 0.245nMAssay Description:Displacement of [3H]epibatidine from rat alpha4beta2 nAChRMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Rattus norvegicus (Rat))
The University Of Queensland
Curated by ChEMBL
The University Of Queensland
Curated by ChEMBL
Affinity DataIC50: 0.280nMAssay Description:Inhibition of rat Nicotinic acetylcholine receptor alpha3-beta2 expressed in Xenopus OocytesMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Rattus norvegicus (Rat))
The University Of Queensland
Curated by ChEMBL
The University Of Queensland
Curated by ChEMBL
Affinity DataIC50: 0.280nMAssay Description:Antagonist activity at rat alpha3beta2 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response at -70 mV holding potential...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Rattus norvegicus (Rat))
The University Of Queensland
Curated by ChEMBL
The University Of Queensland
Curated by ChEMBL
Affinity DataIC50: 0.280nMAssay Description:Antagonist activity at rat alpha3beta2 nACHR expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced response at -70 mV holding pot...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Rattus norvegicus (Rat))
The University Of Queensland
Curated by ChEMBL
The University Of Queensland
Curated by ChEMBL
Affinity DataIC50: 0.290nMAssay Description:Antagonist activity at rat alpha3beta2 nACHR expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced response at -70 mV holding pot...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Rattus norvegicus (Rat))
The University Of Queensland
Curated by ChEMBL
The University Of Queensland
Curated by ChEMBL
Affinity DataIC50: 0.300nMAssay Description:Inhibition of rat Nicotinic acetylcholine receptor alpha3-beta2 expressed in Xenopus OocytesMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Affinity DataIC50: 0.309nMAssay Description:Displacement of [3H]epibatidine from rat alpha4beta2 nAChRMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Rattus norvegicus (Rat))
The University Of Queensland
Curated by ChEMBL
The University Of Queensland
Curated by ChEMBL
Affinity DataIC50: 0.380nMAssay Description:Antagonist activity at rat alpha3beta2 nACHR expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced response at -70 mV holding pot...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Affinity DataIC50: 0.380nMAssay Description:Inhibition of [3H]cytisine binding to alpha4beta2 nACHR in Wistar rat cerebral cortical membraneMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Affinity DataIC50: 0.450nMAssay Description:Inhibition of [3H]cytisine binding to alpha4beta2 nACHR in Wistar rat cerebral cortical membraneMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Rattus norvegicus (Rat))
The University Of Queensland
Curated by ChEMBL
The University Of Queensland
Curated by ChEMBL
Affinity DataIC50: 0.5nMAssay Description:Inhibition of rat Nicotinic acetylcholine receptor alpha3-beta2 expressed in Xenopus OocytesMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Rattus norvegicus (Rat))
The University Of Queensland
Curated by ChEMBL
The University Of Queensland
Curated by ChEMBL
Affinity DataIC50: 0.540nMAssay Description:Inhibition of rat Nicotinic acetylcholine receptor alpha3-beta2 expressed in Xenopus OocytesMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Rattus norvegicus (Rat))
The University Of Queensland
Curated by ChEMBL
The University Of Queensland
Curated by ChEMBL
Affinity DataIC50: 0.570nMAssay Description:Antagonist activity at rat alpha3beta2 nACHR expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced response at -70 mV holding pot...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Affinity DataIC50: 0.640nMAssay Description:Inhibition of [3H]cytisine binding to alpha4beta2 nACHR in Wistar rat cerebral cortical membraneMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Affinity DataIC50: 0.680nMAssay Description:In vitro binding affinity for Nicotinic acetylcholine receptor alpha4-beta2 (alpha4 beta-2 subtype of nAChRs) in rat cerebral cortical membrane using...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Affinity DataIC50: 0.870nMAssay Description:In vitro binding affinity for Nicotinic acetylcholine receptor alpha4-beta2 (alpha4 beta-2 subtype of nAChRs) in rat cerebral cortical membrane using...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Affinity DataIC50: 0.900nMAssay Description:Inhibition of [3H]cytisine binding to alpha4beta2 nACHR in Wistar rat cerebral cortical membraneMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Affinity DataIC50: 0.910nMAssay Description:Inhibition of [3H](-)-nicotine binding to recombinant rat alpha4-beta2 nAChR.More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:In vitro binding affinity for Nicotinic acetylcholine receptor alpha4-beta2 (alpha4 beta-2 subtype of nAChRs) in rat cerebral cortical membrane using...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of [3H]cytisine binding to alpha4beta2 nACHR in Wistar rat cerebral cortical membraneMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Rattus norvegicus (Rat))
The University Of Queensland
Curated by ChEMBL
The University Of Queensland
Curated by ChEMBL
Affinity DataIC50: 1.10nMAssay Description:Inhibition of rat Nicotinic acetylcholine receptor alpha3-beta2 expressed in Xenopus OocytesMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Rattus norvegicus (Rat))
The University Of Queensland
Curated by ChEMBL
The University Of Queensland
Curated by ChEMBL
Affinity DataIC50: 1.20nMAssay Description:Antagonist activity at rat alpha3beta2 nACHR expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced response at -70 mV holding pot...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Rattus norvegicus (Rat))
The University Of Queensland
Curated by ChEMBL
The University Of Queensland
Curated by ChEMBL
Affinity DataIC50: 1.30nMAssay Description:Antagonist activity at rat alpha3beta2 nACHR expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced response at -70 mV holding pot...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Rattus norvegicus (Rat))
The University Of Queensland
Curated by ChEMBL
The University Of Queensland
Curated by ChEMBL
Affinity DataIC50: 1.30nMAssay Description:Antagonist activity at rat alpha3beta2 nACHR expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced response at -70 mV holding pot...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Rattus norvegicus (Rat))
The University Of Queensland
Curated by ChEMBL
The University Of Queensland
Curated by ChEMBL
Affinity DataIC50: 1.30nMAssay Description:Antagonist activity at rat alpha3beta2 nACHR expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced response at -70 mV holding pot...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Rattus norvegicus (Rat))
The University Of Queensland
Curated by ChEMBL
The University Of Queensland
Curated by ChEMBL
Affinity DataIC50: 1.30nMAssay Description:Antagonist activity at rat alpha3beta2 nACHR expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced response at -70 mV holding pot...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Rattus norvegicus (Rat))
The University Of Queensland
Curated by ChEMBL
The University Of Queensland
Curated by ChEMBL
Affinity DataIC50: 1.30nMAssay Description:Inhibition of rat alpha3beta2 expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced channel current response at -70 mV ...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Affinity DataIC50: 1.30nMAssay Description:Inhibition of [3H]cytisine binding to alpha4beta2 nACHR in Wistar rat cerebral cortical membraneMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Affinity DataIC50: 1.40nMAssay Description:Inhibition of [3H]cytisine binding to alpha4beta2 nACHR in Wistar rat cerebral cortical membraneMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Affinity DataIC50: 1.40nMAssay Description:Inhibition of [3H]cytisine binding to alpha4beta2 nACHR in Wistar rat cerebral cortical membraneMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Rattus norvegicus (Rat))
The University Of Queensland
Curated by ChEMBL
The University Of Queensland
Curated by ChEMBL
Affinity DataIC50: 1.70nMAssay Description:Antagonist activity at rat alpha3beta2 nACHR expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced response at -70 mV holding pot...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Affinity DataIC50: 1.80nMAssay Description:Inhibition of [3H]cytisine binding to alpha4beta2 nACHR in Wistar rat cerebral cortical membraneMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Affinity DataIC50: 1.90nMAssay Description:Inhibition of [3H]cytisine binding to alpha4beta2 nACHR in Wistar rat cerebral cortical membraneMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Affinity DataIC50: 1.90nMAssay Description:Inhibition of [3H](-)-nicotine binding to recombinant rat alpha4-beta2 nAChR.More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of [3H]cytisine binding to alpha4beta2 nACHR in Wistar rat cerebral cortical membraneMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Rattus norvegicus (Rat))
The University Of Queensland
Curated by ChEMBL
The University Of Queensland
Curated by ChEMBL
Affinity DataIC50: 2.10nMAssay Description:Antagonist activity at rat alpha3beta2 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced response at -70 mV holding pot...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Rattus norvegicus (Rat))
The University Of Queensland
Curated by ChEMBL
The University Of Queensland
Curated by ChEMBL
Affinity DataIC50: 2.20nMAssay Description:Antagonist activity at rat alpha3beta2 nACHR expressed in Xenopus laevis oocytes by two electrode voltage-clamp assayMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Affinity DataIC50: 2.30nMAssay Description:Inhibition of [3H](-)-nicotine binding to recombinant rat alpha4-beta2 nAChR.More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Affinity DataIC50: 2.80nMAssay Description:Inhibition of [3H](-)-nicotine binding to recombinant rat alpha4-beta2 nAChR.More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Affinity DataIC50: 2.80nMAssay Description:Inhibition of [3H]cytisine binding to alpha4beta2 nACHR in Wistar rat cerebral cortical membraneMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Rattus norvegicus (Rat))
The University Of Queensland
Curated by ChEMBL
The University Of Queensland
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Antagonist activity at rat alpha3beta2 nACHR expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced response at -70 mV holding pot...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of [3H]cytisine binding to alpha4beta2 nACHR in Wistar rat cerebral cortical membraneMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Affinity DataIC50: 3.10nMAssay Description:Inhibition of [3H]cytisine binding to alpha4beta2 nACHR in Wistar rat cerebral cortical membraneMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/alpha-6/beta-2/beta-3(Rattus norvegicus (Rat))
Veterans Affairs Medical Center
Curated by ChEMBL
Veterans Affairs Medical Center
Curated by ChEMBL
Affinity DataIC50: 3.10nMAssay Description:Inhibition of rat alpha6/alpha3beta2beta3 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced current response ...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Rattus norvegicus (Rat))
The University Of Queensland
Curated by ChEMBL
The University Of Queensland
Curated by ChEMBL
Affinity DataIC50: 3.20nMAssay Description:Antagonist activity at rat alpha3beta2 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced response at -70 mV holding pot...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Rattus norvegicus (Rat))
The University Of Queensland
Curated by ChEMBL
The University Of Queensland
Curated by ChEMBL
Affinity DataIC50: 3.40nMAssay Description:Antagonist activity at rat alpha3beta2 nACHR expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced response at -70 mV holding pot...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Affinity DataIC50: 3.5nMAssay Description:Inhibition of [3H](-)-nicotine binding to recombinant rat alpha4-beta2 nAChR.More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Affinity DataIC50: 3.80nMAssay Description:Inhibition of [3H](-)-nicotine binding to recombinant rat alpha4-beta2 nAChR.More data for this Ligand-Target Pair