Compile Data Set for Download or QSAR
maximum 50k data
Found 2423 of ic50 for UniProtKB: P21589
Target5'-nucleotidase(Homo sapiens (Human))
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50546288(CHEMBL4743437)
Affinity DataIC50:  0.00270nMAssay Description:Inhibition of CD73 in human CD8-positive T cells using AMP as substrate preincubated for 60 mins followed by substrate addition and measured after 2....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5'-nucleotidase(Homo sapiens (Human))
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50527134(CHEMBL4471306 | US20230295213, Compound a)
Affinity DataIC50:  0.00800nMAssay Description:Inhibition of CD73 in human CD8-positive T cells using AMP as substrate preincubated for 60 mins followed by substrate addition and measured after 2....More data for this Ligand-Target Pair
Target5'-nucleotidase(Homo sapiens (Human))
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50546288(CHEMBL4743437)
Affinity DataIC50:  0.00850nMAssay Description:Inhibition of CD73 in human PBMC using AMP as substrate preincubated for 60 mins followed by substrate addition and measured after 2.5 hrs by PiColor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5'-nucleotidase(Homo sapiens (Human))
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50546280(CHEMBL4761506)
Affinity DataIC50:  0.0100nMAssay Description:Inhibition of CD73 in human CD8-positive T cells using AMP as substrate preincubated for 60 mins followed by substrate addition and measured after 2....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
Target5'-nucleotidase(Homo sapiens (Human))
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50527134(CHEMBL4471306 | US20230295213, Compound a)
Affinity DataIC50:  0.0110nMAssay Description:Inhibition of CD73 in human PBMC using AMP as substrate preincubated for 60 mins followed by substrate addition and measured after 2.5 hrs by PiColor...More data for this Ligand-Target Pair
Target5'-nucleotidase(Homo sapiens (Human))
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM554453(US11332492, Example 2)
Affinity DataIC50:  0.0130nMAssay Description:I. Experimental Materials and Equipment1. Malachite green phosphate detection kit (R & D Systems, Cat #, DY996)2. Recombinant human 5′-nucleoti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5'-nucleotidase(Homo sapiens (Human))
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50546280(CHEMBL4761506)
Affinity DataIC50:  0.0210nMAssay Description:Inhibition of CD73 in human PBMC using AMP as substrate preincubated for 60 mins followed by substrate addition and measured after 2.5 hrs by PiColor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
Target5'-nucleotidase(Homo sapiens (Human))
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50546290(CHEMBL4749428)
Affinity DataIC50:  0.0270nMAssay Description:Inhibition of human CD73 expressed in CHO cells using AMP as substrate preincubated for 60 mins followed by substrate addition and measured after 60 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5'-nucleotidase(Homo sapiens (Human))
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50546285(CHEMBL4776758)
Affinity DataIC50:  0.0280nMAssay Description:Inhibition of human CD73 expressed in CHO cells using AMP as substrate preincubated for 60 mins followed by substrate addition and measured after 60 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5'-nucleotidase(Homo sapiens (Human))
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50546281(CHEMBL4746184)
Affinity DataIC50:  0.0310nMAssay Description:Inhibition of human CD73 expressed in CHO cells using AMP as substrate preincubated for 60 mins followed by substrate addition and measured after 60 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5'-nucleotidase(Homo sapiens (Human))
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50546284(CHEMBL4740465)
Affinity DataIC50:  0.0310nMAssay Description:Inhibition of human CD73 expressed in CHO cells using AMP as substrate preincubated for 60 mins followed by substrate addition and measured after 60 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5'-nucleotidase(Homo sapiens (Human))
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50546283(CHEMBL4797225)
Affinity DataIC50:  0.0320nMAssay Description:Inhibition of human CD73 expressed in CHO cells using AMP as substrate preincubated for 60 mins followed by substrate addition and measured after 60 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5'-nucleotidase(Homo sapiens (Human))
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50527134(CHEMBL4471306 | US20230295213, Compound a)
Affinity DataIC50:  0.0410nMAssay Description:Inhibition of human CD73 expressed in CHO cells using AMP as substrate preincubated for 60 mins followed by substrate addition and measured after 60 ...More data for this Ligand-Target Pair
Target5'-nucleotidase(Homo sapiens (Human))
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50527134(CHEMBL4471306 | US20230295213, Compound a)
Affinity DataIC50:  0.0430nMAssay Description:Inhibition of soluble human CD73More data for this Ligand-Target Pair
Target5'-nucleotidase(Homo sapiens (Human))
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50546288(CHEMBL4743437)
Affinity DataIC50:  0.0450nMAssay Description:Inhibition of human CD73 expressed in CHO cells using AMP as substrate preincubated for 60 mins followed by substrate addition and measured after 60 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5'-nucleotidase(Homo sapiens (Human))
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM511228(2-(((2R,3S,4R,5R)-5-(6-amino-2-chloro-9H-purin-9-y...)
Affinity DataIC50:  0.0500nMAssay Description:For measurements of soluble CD73 enzyme activity, recombinant CD73 was obtained from R&D Systems, Cat. No. 5795-EN-010. Serial dilutions of test comp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5'-nucleotidase(Homo sapiens (Human))
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50546289(CHEMBL4790144)
Affinity DataIC50:  0.0520nMAssay Description:Inhibition of human CD73 expressed in CHO cells using AMP as substrate preincubated for 60 mins followed by substrate addition and measured after 60 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5'-nucleotidase(Homo sapiens (Human))
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50546288(CHEMBL4743437)
Affinity DataIC50:  0.0530nMAssay Description:Inhibition of soluble human CD73More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5'-nucleotidase(Homo sapiens (Human))
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50546287(CHEMBL4745002)
Affinity DataIC50:  0.0580nMAssay Description:Inhibition of human CD73 expressed in CHO cells using AMP as substrate preincubated for 60 mins followed by substrate addition and measured after 60 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5'-nucleotidase(Homo sapiens (Human))
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM511078(2-(((2R,3S,4R,5R)-5-(6-amino-2-chloro-9H-purin-9-y...)
Affinity DataIC50:  0.0600nMAssay Description:For measurements of soluble CD73 enzyme activity, recombinant CD73 was obtained from R&D Systems, Cat. No. 5795-EN-010. Serial dilutions of test comp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5'-nucleotidase(Homo sapiens (Human))
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50546286(CHEMBL4784155)
Affinity DataIC50:  0.0700nMAssay Description:Inhibition of human CD73 expressed in CHO cells using AMP as substrate preincubated for 60 mins followed by substrate addition and measured after 60 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5'-nucleotidase(Homo sapiens (Human))
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM554456(US11332492, Example 5)
Affinity DataIC50:  0.0740nMAssay Description:I. Experimental Materials and Equipment1. Malachite green phosphate detection kit (R & D Systems, Cat #, DY996)2. Recombinant human 5′-nucleoti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5'-nucleotidase(Homo sapiens (Human))
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM511224(2-(((2R,3S,4R,5R)-5-(2-chloro-6-(methylamino)-9H-p...)
Affinity DataIC50:  0.0800nMAssay Description:For measurements of soluble CD73 enzyme activity, recombinant CD73 was obtained from R&D Systems, Cat. No. 5795-EN-010. Serial dilutions of test comp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5'-nucleotidase(Homo sapiens (Human))
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50546282(CHEMBL4777161)
Affinity DataIC50:  0.0950nMAssay Description:Inhibition of human CD73 expressed in CHO cells using AMP as substrate preincubated for 60 mins followed by substrate addition and measured after 60 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5'-nucleotidase(Homo sapiens (Human))
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM511079(2-(((2R,3S,4R,5R)-5-(6-amino-2-chloro-9H-purin-9-y...)
Affinity DataIC50:  0.100nMAssay Description:For measurements of soluble CD73 enzyme activity, recombinant CD73 was obtained from R&D Systems, Cat. No. 5795-EN-010. Serial dilutions of test comp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5'-nucleotidase(Homo sapiens (Human))
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM554452(US11332492, Example 1)
Affinity DataIC50:  0.110nMAssay Description:I. Experimental Materials and Equipment1. Malachite green phosphate detection kit (R & D Systems, Cat #, DY996)2. Recombinant human 5′-nucleoti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5'-nucleotidase(Homo sapiens (Human))
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM511225(2-(((2R,3S,4R,5R)-5-(6-amino-2-chloro-9H-purin-9-y...)
Affinity DataIC50:  0.110nMAssay Description:For measurements of soluble CD73 enzyme activity, recombinant CD73 was obtained from R&D Systems, Cat. No. 5795-EN-010. Serial dilutions of test comp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5'-nucleotidase(Homo sapiens (Human))
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50546280(CHEMBL4761506)
Affinity DataIC50:  0.115nMAssay Description:Inhibition of human CD73 expressed in CHO cells using AMP as substrate preincubated for 60 mins followed by substrate addition and measured after 60 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
Target5'-nucleotidase(Homo sapiens (Human))
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50546324(CHEMBL4753354)
Affinity DataIC50:  0.120nMAssay Description:Inhibition of human CD73 expressed in CHO cells using AMP as substrate preincubated for 60 mins followed by substrate addition and measured after 60 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5'-nucleotidase(Homo sapiens (Human))
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM650341(US20240043427, Example 436)
Affinity DataIC50:  0.130nMAssay Description:Compound serial dilutions were pre-spotted into Thermo Nunc assay plate. 50 uL CD73 enzyme buffer (CD73 purchased from R&D system=0.6 nM, 25 mM Tris,...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
Target5'-nucleotidase(Homo sapiens (Human))
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM511215(2-(((2R,3S,4R,5R)-5-(2-chloro-6-(isopropylamino)-9...)
Affinity DataIC50:  0.130nMAssay Description:For measurements of soluble CD73 enzyme activity, recombinant CD73 was obtained from R&D Systems, Cat. No. 5795-EN-010. Serial dilutions of test comp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5'-nucleotidase(Homo sapiens (Human))
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM554473(US11332492, Example 7)
Affinity DataIC50:  0.130nMAssay Description:I. Experimental Materials and Equipment1. Malachite green phosphate detection kit (R & D Systems, Cat #, DY996)2. Recombinant human 5′-nucleoti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5'-nucleotidase(Homo sapiens (Human))
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM511232(2-(((2R,3S,4R,5R)-5-(5-chloro-7-((2,4-dimethoxyben...)
Affinity DataIC50:  0.140nMAssay Description:For measurements of soluble CD73 enzyme activity, recombinant CD73 was obtained from R&D Systems, Cat. No. 5795-EN-010. Serial dilutions of test comp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5'-nucleotidase(Homo sapiens (Human))
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM650343(US20240043427, Example 438)
Affinity DataIC50:  0.140nMAssay Description:Compound serial dilutions were pre-spotted into Thermo Nunc assay plate. 50 uL CD73 enzyme buffer (CD73 purchased from R&D system=0.6 nM, 25 mM Tris,...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
Target5'-nucleotidase(Homo sapiens (Human))
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM650336(US20240043427, Example 431)
Affinity DataIC50:  0.150nMAssay Description:Compound serial dilutions were pre-spotted into Thermo Nunc assay plate. 50 uL CD73 enzyme buffer (CD73 purchased from R&D system=0.6 nM, 25 mM Tris,...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
Target5'-nucleotidase(Homo sapiens (Human))
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM650337(US20240043427, Example 432)
Affinity DataIC50:  0.150nMAssay Description:Compound serial dilutions were pre-spotted into Thermo Nunc assay plate. 50 uL CD73 enzyme buffer (CD73 purchased from R&D system=0.6 nM, 25 mM Tris,...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
Target5'-nucleotidase(Homo sapiens (Human))
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50546294(CHEMBL4763896)
Affinity DataIC50:  0.150nMAssay Description:Inhibition of human CD73 expressed in CHO cells using AMP as substrate preincubated for 60 mins followed by substrate addition and measured after 60 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5'-nucleotidase(Homo sapiens (Human))
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM511214(2-(((2R,3S,4R,5R)-5-(2-chloro-6-((cyclopropylmethy...)
Affinity DataIC50:  0.150nMAssay Description:For measurements of soluble CD73 enzyme activity, recombinant CD73 was obtained from R&D Systems, Cat. No. 5795-EN-010. Serial dilutions of test comp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5'-nucleotidase(Homo sapiens (Human))
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50546325(CHEMBL4758486)
Affinity DataIC50:  0.150nMAssay Description:Inhibition of human CD73 expressed in CHO cells using AMP as substrate preincubated for 60 mins followed by substrate addition and measured after 60 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5'-nucleotidase(Homo sapiens (Human))
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM511226(2-(((2R,3S,4R,5R)-5-(2-chloro-6-((cyclopropylmethy...)
Affinity DataIC50:  0.160nMAssay Description:For measurements of soluble CD73 enzyme activity, recombinant CD73 was obtained from R&D Systems, Cat. No. 5795-EN-010. Serial dilutions of test comp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5'-nucleotidase(Homo sapiens (Human))
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM511076(2-(((2R,3S,4R,5R)-5-(6-amino-2-chloro-9H-purin-9-y...)
Affinity DataIC50:  0.170nMAssay Description:For measurements of soluble CD73 enzyme activity, recombinant CD73 was obtained from R&D Systems, Cat. No. 5795-EN-010. Serial dilutions of test comp...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5'-nucleotidase(Homo sapiens (Human))
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM650335(US20240043427, Example 430)
Affinity DataIC50:  0.180nMAssay Description:Compound serial dilutions were pre-spotted into Thermo Nunc assay plate. 50 uL CD73 enzyme buffer (CD73 purchased from R&D system=0.6 nM, 25 mM Tris,...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
Target5'-nucleotidase(Homo sapiens (Human))
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM650528(US20240043427, Example 629)
Affinity DataIC50:  0.200nMAssay Description:Compound serial dilutions were pre-spotted into Thermo Nunc assay plate. 50 uL CD73 enzyme buffer (CD73 purchased from R&D system=0.6 nM, 25 mM Tris,...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
Target5'-nucleotidase(Homo sapiens (Human))
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50546326(CHEMBL4744502)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of human CD73 expressed in CHO cells using AMP as substrate preincubated for 60 mins followed by substrate addition and measured after 60 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5'-nucleotidase(Homo sapiens (Human))
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM511125(2-(((2R,3S,4R,5R)-5-(6-amino-2-chloro-9H-purin-9-y...)
Affinity DataIC50:  0.200nMAssay Description:For measurements of soluble CD73 enzyme activity, recombinant CD73 was obtained from R&D Systems, Cat. No. 5795-EN-010. Serial dilutions of test comp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5'-nucleotidase(Homo sapiens (Human))
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM511089(2-(((2R,3S,4R,5R)-5-(6-amino-2-chloro-9H-purin-9-y...)
Affinity DataIC50:  0.200nMAssay Description:For measurements of soluble CD73 enzyme activity, recombinant CD73 was obtained from R&D Systems, Cat. No. 5795-EN-010. Serial dilutions of test comp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5'-nucleotidase(Homo sapiens (Human))
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM511088(2-(((2R,3S,4R,5R)-5-(6-amino-2-chloro-9H-purin-9-y...)
Affinity DataIC50:  0.200nMAssay Description:For measurements of soluble CD73 enzyme activity, recombinant CD73 was obtained from R&D Systems, Cat. No. 5795-EN-010. Serial dilutions of test comp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5'-nucleotidase(Homo sapiens (Human))
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM650154(US20240043427, Example 242)
Affinity DataIC50:  0.220nMAssay Description:Compound serial dilutions were pre-spotted into Thermo Nunc assay plate. 50 uL CD73 enzyme buffer (CD73 purchased from R&D system=0.6 nM, 25 mM Tris,...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
Target5'-nucleotidase(Homo sapiens (Human))
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM650331(US20240043427, Example 426)
Affinity DataIC50:  0.230nMAssay Description:Compound serial dilutions were pre-spotted into Thermo Nunc assay plate. 50 uL CD73 enzyme buffer (CD73 purchased from R&D system=0.6 nM, 25 mM Tris,...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
Target5'-nucleotidase(Homo sapiens (Human))
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM511217(2-(((2R,3S,4R,5R)-5-(2-chloro-6-(methylamino)-9H-p...)
Affinity DataIC50:  0.230nMAssay Description:For measurements of soluble CD73 enzyme activity, recombinant CD73 was obtained from R&D Systems, Cat. No. 5795-EN-010. Serial dilutions of test comp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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