Compile Data Set for Download or QSAR
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Found 872 of ic50 for UniProtKB: Q16769
TargetGlutaminyl-peptide cyclotransferase(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50581458(CHEMBL5092802)
Affinity DataIC50:  0.100nMAssay Description:Inhibition of human recombinant glutaminyl cyclase using H-Gln-AMC hydrobromide as substrate measured after 15 mins by fluorimetryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetGlutaminyl-peptide cyclotransferase(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50581397(CHEMBL5085353)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of human recombinant glutaminyl cyclase using H-Gln-AMC hydrobromide as substrate measured after 15 mins by fluorimetryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutaminyl-peptide cyclotransferase(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50581442(CHEMBL5086776)
Affinity DataIC50:  0.460nMAssay Description:Inhibition of human recombinant glutaminyl cyclase using H-Gln-AMC hydrobromide as substrate measured after 15 mins by fluorimetryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutaminyl-peptide cyclotransferase(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50581399(CHEMBL5085226)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of human recombinant glutaminyl cyclase using H-Gln-AMC hydrobromide as substrate measured after 15 mins by fluorimetryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutaminyl-peptide cyclotransferase(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50581400(CHEMBL5075575)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of human recombinant glutaminyl cyclase using H-Gln-AMC hydrobromide as substrate measured after 15 mins by fluorimetryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutaminyl-peptide cyclotransferase(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50237486(CHEMBL4077433)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of human glutaminyl cyclase assessed as reduction in conversion of H-Gln-AMC hydrobromide to pGlu-AMC preincubated with substrate for 10 m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutaminyl-peptide cyclotransferase(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50581426(CHEMBL5089771)
Affinity DataIC50:  0.710nMAssay Description:Inhibition of human recombinant glutaminyl cyclase using H-Gln-AMC hydrobromide as substrate measured after 15 mins by fluorimetryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutaminyl-peptide cyclotransferase(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50581398(CHEMBL5083519)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of human recombinant glutaminyl cyclase using H-Gln-AMC hydrobromide as substrate measured after 15 mins by fluorimetryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutaminyl-peptide cyclotransferase(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM652363(US20240059675, Example 32)
Affinity DataIC50:  1nMAssay Description:QPCT or QPCTL dependent conversion of N-terminal glutamine to pyroglutamate of CD47 was monitored via MALDI-TOF MS. Test compounds were dissolved in ...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetGlutaminyl-peptide cyclotransferase(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM652305(US20240059675, Example 8)
Affinity DataIC50:  1nMAssay Description:QPCT or QPCTL dependent conversion of N-terminal glutamine to pyroglutamate of CD47 was monitored via MALDI-TOF MS. Test compounds were dissolved in ...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetGlutaminyl-peptide cyclotransferase(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50581450(CHEMBL5085670)
Affinity DataIC50:  1nMAssay Description:Inhibition of human recombinant glutaminyl cyclase using H-Gln-AMC hydrobromide as substrate measured after 15 mins by fluorimetryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutaminyl-peptide cyclotransferase(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM652310(US20240059675, Example 13)
Affinity DataIC50:  1nMAssay Description:QPCT or QPCTL dependent conversion of N-terminal glutamine to pyroglutamate of CD47 was monitored via MALDI-TOF MS. Test compounds were dissolved in ...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetGlutaminyl-peptide cyclotransferase(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM652312(US20240059675, Example 15)
Affinity DataIC50:  1nMAssay Description:QPCT or QPCTL dependent conversion of N-terminal glutamine to pyroglutamate of CD47 was monitored via MALDI-TOF MS. Test compounds were dissolved in ...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetGlutaminyl-peptide cyclotransferase(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM652324(US20240059675, Example 26)
Affinity DataIC50:  1nMAssay Description:QPCT or QPCTL dependent conversion of N-terminal glutamine to pyroglutamate of CD47 was monitored via MALDI-TOF MS. Test compounds were dissolved in ...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetGlutaminyl-peptide cyclotransferase(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50581412(CHEMBL5088732)
Affinity DataIC50:  1nMAssay Description:Inhibition of human recombinant glutaminyl cyclase using H-Gln-AMC hydrobromide as substrate measured after 15 mins by fluorimetryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutaminyl-peptide cyclotransferase(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50519290(CHEMBL4525926)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of recombinant human N-terminal His6-tagged glutaminyl cyclase (Ala33 to Leu361 residues) expressed in baculovirus infected Sf21 insect ce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutaminyl-peptide cyclotransferase(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50581445(CHEMBL5089285)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of human recombinant glutaminyl cyclase using H-Gln-AMC hydrobromide as substrate measured after 15 mins by fluorimetryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutaminyl-peptide cyclotransferase(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50581441(CHEMBL5081653)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of human recombinant glutaminyl cyclase using H-Gln-AMC hydrobromide as substrate measured after 15 mins by fluorimetryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutaminyl-peptide cyclotransferase(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50581443(CHEMBL5083687)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of human recombinant glutaminyl cyclase using H-Gln-AMC hydrobromide as substrate measured after 15 mins by fluorimetryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutaminyl-peptide cyclotransferase(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50581436(CHEMBL5081891)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of human recombinant glutaminyl cyclase using H-Gln-AMC hydrobromide as substrate measured after 15 mins by fluorimetryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutaminyl-peptide cyclotransferase(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50519285(CHEMBL4445407)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of recombinant human N-terminal His6-tagged glutaminyl cyclase (Ala33 to Leu361 residues) expressed in baculovirus infected Sf21 insect ce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutaminyl-peptide cyclotransferase(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50581434(CHEMBL5081537)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of human recombinant glutaminyl cyclase using H-Gln-AMC hydrobromide as substrate measured after 15 mins by fluorimetryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutaminyl-peptide cyclotransferase(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50581451(CHEMBL5092925)
Affinity DataIC50:  1.80nMAssay Description:Inhibition of human recombinant glutaminyl cyclase using H-Gln-AMC hydrobromide as substrate measured after 15 mins by fluorimetryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutaminyl-peptide cyclotransferase(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50454733(CHEMBL4204093)
Affinity DataIC50:  1.80nMAssay Description:Inhibition of human glutaminyl cyclase using Gln-AMC as substrate by pGAPase coupled fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutaminyl-peptide cyclotransferase(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM652309(US20240059675, Example 12)
Affinity DataIC50:  2nMAssay Description:QPCT or QPCTL dependent conversion of N-terminal glutamine to pyroglutamate of CD47 was monitored via MALDI-TOF MS. Test compounds were dissolved in ...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetGlutaminyl-peptide cyclotransferase(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM652328(US20240059675, Example 30)
Affinity DataIC50:  2nMAssay Description:QPCT or QPCTL dependent conversion of N-terminal glutamine to pyroglutamate of CD47 was monitored via MALDI-TOF MS. Test compounds were dissolved in ...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetGlutaminyl-peptide cyclotransferase(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM652299(US20240059675, Example 3)
Affinity DataIC50:  2nMAssay Description:QPCT or QPCTL dependent conversion of N-terminal glutamine to pyroglutamate of CD47 was monitored via MALDI-TOF MS. Test compounds were dissolved in ...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetGlutaminyl-peptide cyclotransferase(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50612645(CHEMBL5279792)
Affinity DataIC50:  2.30nMAssay Description:Inhibition of human glutaminyl cyclase using L-glutamine-7-amido-4-methylcoumarin as substrate incubated for 10 mins in presence of pyroglutamyl pept...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetGlutaminyl-peptide cyclotransferase(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50612631(CHEMBL5266674)
Affinity DataIC50:  2.30nMAssay Description:Inhibition of human glutaminyl cyclase using L-glutamine-7-amido-4-methylcoumarin as substrate incubated for 10 mins in presence of pyroglutamyl pept...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetGlutaminyl-peptide cyclotransferase(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50581448(CHEMBL5094369)
Affinity DataIC50:  2.60nMAssay Description:Inhibition of human recombinant glutaminyl cyclase using H-Gln-AMC hydrobromide as substrate measured after 15 mins by fluorimetryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutaminyl-peptide cyclotransferase(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50581460(CHEMBL5084485)
Affinity DataIC50:  2.60nMAssay Description:Inhibition of human recombinant glutaminyl cyclase using H-Gln-AMC hydrobromide as substrate measured after 15 mins by fluorimetryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutaminyl-peptide cyclotransferase(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50581422(CHEMBL5079181)
Affinity DataIC50:  2.70nMAssay Description:Inhibition of human recombinant glutaminyl cyclase using H-Gln-AMC hydrobromide as substrate measured after 15 mins by fluorimetryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutaminyl-peptide cyclotransferase(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50519280(CHEMBL4464130)
Affinity DataIC50:  2.80nMAssay Description:Inhibition of recombinant human N-terminal His6-tagged glutaminyl cyclase (Ala33 to Leu361 residues) expressed in baculovirus infected Sf21 insect ce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutaminyl-peptide cyclotransferase(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50581410(CHEMBL5081843)
Affinity DataIC50:  2.80nMAssay Description:Inhibition of human recombinant glutaminyl cyclase using H-Gln-AMC hydrobromide as substrate measured after 15 mins by fluorimetryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutaminyl-peptide cyclotransferase(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM652327(US20240059675, Example 29)
Affinity DataIC50:  3nMAssay Description:QPCT or QPCTL dependent conversion of N-terminal glutamine to pyroglutamate of CD47 was monitored via MALDI-TOF MS. Test compounds were dissolved in ...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetGlutaminyl-peptide cyclotransferase(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM652330(US20240059675, Example 31)
Affinity DataIC50:  3nMAssay Description:QPCT or QPCTL dependent conversion of N-terminal glutamine to pyroglutamate of CD47 was monitored via MALDI-TOF MS. Test compounds were dissolved in ...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetGlutaminyl-peptide cyclotransferase(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM652326(US20240059675, Example 28)
Affinity DataIC50:  3nMAssay Description:QPCT or QPCTL dependent conversion of N-terminal glutamine to pyroglutamate of CD47 was monitored via MALDI-TOF MS. Test compounds were dissolved in ...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetGlutaminyl-peptide cyclotransferase(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM652318(US20240059675, Example 21)
Affinity DataIC50:  3nMAssay Description:QPCT or QPCTL dependent conversion of N-terminal glutamine to pyroglutamate of CD47 was monitored via MALDI-TOF MS. Test compounds were dissolved in ...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetGlutaminyl-peptide cyclotransferase(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50612648(CHEMBL5266206)
Affinity DataIC50:  3nMAssay Description:Inhibition of human glutaminyl cyclase using L-glutamine-7-amido-4-methylcoumarin as substrate incubated for 10 mins in presence of pyroglutamyl pept...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetGlutaminyl-peptide cyclotransferase(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM149365(US8962860, 9)
Affinity DataKi:  3.24nM ΔG°:  -11.8kcal/mole IC50:  3.08nMT: 2°CAssay Description:This novel assay was used to determine the kinetic parameters for most of the QC substrates. QC activity was analyzed spectrophotometrically using a ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlutaminyl-peptide cyclotransferase(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50612627(CHEMBL5282127)
Affinity DataIC50:  3.20nMAssay Description:Inhibition of human glutaminyl cyclase using L-glutamine-7-amido-4-methylcoumarin as substrate incubated for 10 mins in presence of pyroglutamyl pept...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetGlutaminyl-peptide cyclotransferase(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50581453(CHEMBL5076836)
Affinity DataIC50:  3.20nMAssay Description:Inhibition of human recombinant glutaminyl cyclase using H-Gln-AMC hydrobromide as substrate measured after 15 mins by fluorimetryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutaminyl-peptide cyclotransferase(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50519269(CHEMBL4539841)
Affinity DataIC50:  3.40nMAssay Description:Inhibition of recombinant human N-terminal His6-tagged glutaminyl cyclase (Ala33 to Leu361 residues) expressed in baculovirus infected Sf21 insect ce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutaminyl-peptide cyclotransferase(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50581473(CHEMBL5088100)
Affinity DataIC50:  3.40nMAssay Description:Inhibition of human recombinant glutaminyl cyclase using H-Gln-AMC hydrobromide as substrate measured after 15 mins by fluorimetryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutaminyl-peptide cyclotransferase(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50581409(CHEMBL5088413)
Affinity DataIC50:  3.40nMAssay Description:Inhibition of human recombinant glutaminyl cyclase using H-Gln-AMC hydrobromide as substrate measured after 15 mins by fluorimetryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutaminyl-peptide cyclotransferase(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50612630(CHEMBL5289328)
Affinity DataIC50:  3.40nMAssay Description:Inhibition of human glutaminyl cyclase using L-glutamine-7-amido-4-methylcoumarin as substrate incubated for 10 mins in presence of pyroglutamyl pept...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetGlutaminyl-peptide cyclotransferase(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50519268(CHEMBL4586501)
Affinity DataIC50:  3.5nMAssay Description:Inhibition of recombinant human N-terminal His6-tagged glutaminyl cyclase (Ala33 to Leu361 residues) expressed in baculovirus infected Sf21 insect ce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutaminyl-peptide cyclotransferase(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50581452(CHEMBL5092800)
Affinity DataIC50:  3.5nMAssay Description:Inhibition of human recombinant glutaminyl cyclase using H-Gln-AMC hydrobromide as substrate measured after 15 mins by fluorimetryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutaminyl-peptide cyclotransferase(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50581408(CHEMBL5088872)
Affinity DataIC50:  3.60nMAssay Description:Inhibition of human recombinant glutaminyl cyclase using H-Gln-AMC hydrobromide as substrate measured after 15 mins by fluorimetryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutaminyl-peptide cyclotransferase(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50519240(CHEMBL4547037)
Affinity DataIC50:  3.60nMAssay Description:Inhibition of recombinant human N-terminal His6-tagged glutaminyl cyclase (Ala33 to Leu361 residues) expressed in baculovirus infected Sf21 insect ce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
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