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TargetG-protein coupled receptor 35(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50185(2-hydroxy-4-({4-[5-(2-methyl-3-phenyl-2-propen-1-y...)
Affinity DataIC50:  27nMAssay Description:Antagonist activity at human Gal4-VP16 fused GPR35 expressed in human U2OS cells assessed as beta arrestin translocation by reporter gene assayChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled receptor 35(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM61632(5-[(E)-(tert-butylthiocarbamoylhydrazono)methyl]-1...)
Affinity DataIC50:  200nMAssay Description:Antagonist activity at human Gal4-VP16 fused GPR35 expressed in human U2OS cells assessed as beta arrestin translocation by reporter gene assayChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled receptor 35(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM61632(5-[(E)-(tert-butylthiocarbamoylhydrazono)methyl]-1...)
Affinity DataIC50:  574nMAssay Description:Antagonist activity at C-terminal beta-galactosidase tagged human recombinant GPR35 expressed in CHO cells after 90 mins by beta-arrestin recruitment...Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled receptor 35(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM61632(5-[(E)-(tert-butylthiocarbamoylhydrazono)methyl]-1...)
Affinity DataIC50:  1.04E+4nMAssay Description:Antagonist activity at human GPR35 expressed in human HT29 cells after 1 hr by DMR assayChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed