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DNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL

PNG

BDBM12915(2-(4-Morpholinyl)-8-phenyl-4H-1-benzopyran-4-one |...)

Ki: 6.00E+3nMAssay Description:Competitive inhibition of DNA-PK (unknown origin) in the presence of ATPMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
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Details Article PubMed

Filter my 147 hits

Targets 14▿
- DNA-dependent protein kinase catalytic subunit 106
- Potassium voltage-gated channel subfamily H member 2 5
- Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 3
- Serine-protein kinase ATM 3
- Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform 3
- Cytochrome P450 1A2 3
- Serine/threonine-protein kinase mTOR 3
- Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 3
- Cytochrome P450 2C9 3
- Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform 3
- Cytochrome P450 2C19 3
- Serine/threonine-protein kinase ATR 3
- Cytochrome P450 2D6 3
- Cytochrome P450 3A4 3
Publications 1▿
- J Med Chem 56: 6386-401 (2013) 147
Institutions 1▿
- Newcastle University 147
Affinity: 0.10 to 3.3E+4 nM▿
- Ki 1
- IC50 141
- EC50 5
- Affinity ≤ nM
Xtal structures: 2
Docked structures: 0
Catalog Cmpds: 3