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Found 226
TargetVasopressin V1a/V1b receptor(RAT)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50013633(18-(3-Amino-propyl)-6,15-dibenzyl-3-sec-butyl-16-m...)
Affinity DataKi:  240nMAssay Description:Inhibition of [3H]arginine vasopressin binding to rat liver Vasopressin V1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a/V1b receptor(RAT)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50001309((cyclo-[L-propyl-D-phenylalanyl-L-isoleucyl-D-dehy...)
Affinity DataKi:  730nMAssay Description:Inhibition of [3H]arginine vasopressin binding to rat liver Vasopressin V1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a/V1b receptor(RAT)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50013635(24-(1H-5-imidazolylmethyl)-13-[1-methyl-(1S)-propy...)
Affinity DataKi:  760nMAssay Description:Inhibition of [3H]arginine vasopressin binding to rat liver Vasopressin V1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a/V1b receptor(RAT)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50013637(16,24-dibenzyl-25-methyl-13-[1-methyl-(1S)-propyl]...)
Affinity DataKi:  890nMAssay Description:Inhibition of [3H]arginine vasopressin binding to rat liver Vasopressin V1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a/V1b receptor(RAT)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50013630(16,24-dibenzyl-25-methyl-13-[1-methyl-(1S)-propyl]...)
Affinity DataKi:  970nMAssay Description:Inhibition of [3H]-arginine vasopressin binding to rat kidney medulla Vasopressin V2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a/V1b receptor(RAT)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50013640(18-(3-Amino-propyl)-15-benzyl-3-sec-butyl-6-(1H-in...)
Affinity DataKi:  1.00E+3nMAssay Description:Inhibition of [3H]arginine vasopressin binding to rat liver Vasopressin V1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a/V1b receptor(RAT)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50013628(24-(1H-5-imidazolylmethyl)-16-(1H-3-indolylmethyl)...)
Affinity DataKi:  1.20E+3nMAssay Description:Inhibition of [3H]arginine vasopressin binding to rat liver Vasopressin V1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a/V1b receptor(RAT)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50013632(16,24-dibenzyl-13-[1-methyl-(1S)-propyl]perhydrodi...)
Affinity DataKi:  1.60E+3nMAssay Description:Inhibition of [3H]- oxytocin binding to rat uterine Oxytocin receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a/V1b receptor(RAT)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50013634(24-(1H-5-imidazolylmethyl)-16-(1H-3-indolylmethyl)...)
Affinity DataKi:  2.20E+3nMAssay Description:Inhibition of [3H]arginine vasopressin binding to rat liver Vasopressin V1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a/V1b receptor(RAT)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50013638(24-benzyl-16-(1H-3-indolylmethyl)-25-methyl-13-[1-...)
Affinity DataKi:  3.50E+3nMAssay Description:Inhibition of [3H]arginine vasopressin binding to rat liver Vasopressin V1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a/V1b receptor(RAT)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50001302(14,22-dibenzyl-23-methyl-11-[1-methyl-(1S)-propyl]...)
Affinity DataKi:  9.30E+3nMAssay Description:Inhibition of [3H]arginine vasopressin binding to rat liver Vasopressin V1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a/V1b receptor(RAT)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50013636(22-benzyl-13-(1H-3-indolylmethyl)-23-methyl-10-[1-...)
Affinity DataKi:  9.50E+3nMAssay Description:Inhibition of [3H]arginine vasopressin binding to rat liver Vasopressin V1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a/V1b receptor(RAT)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50013641(16-benzyl-24,25-dimethyl-13-[1-methyl-(1S)-propyl]...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of [3H]arginine vasopressin binding to rat liver Vasopressin V1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a/V1b receptor(RAT)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50013631(24-benzyl-16-(4-ethoxybenzyl)-25-methyl-13-[1-meth...)
Affinity DataKi:  2.00E+4nMAssay Description:Inhibition of [3H]arginine vasopressin binding to rat liver Vasopressin V1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a/V1b receptor(RAT)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50013639(16,24-dibenzyl-13,25-dimethylperhydrodipyrido[1,2-...)
Affinity DataKi: >3.00E+4nMAssay Description:Inhibition of [3H]arginine vasopressin binding to rat liver Vasopressin V1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a/V1b receptor(RAT)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50137948(Biphenyl-2-carboxylic acid [2-[3-(4-methyl-[1,4]di...)
Affinity DataIC50:  2nMAssay Description:Inhibitory activity against arginine vasopressin V1 receptor using [3H]AVP as radioligand in rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a/V1b receptor(RAT)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50137945(Biphenyl-2-carboxylic acid [2-[4-(4-methyl-piperaz...)
Affinity DataIC50:  3nMAssay Description:Inhibitory activity against arginine vasopressin V1 receptor using [3H]AVP as radioligand in rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a/V1b receptor(RAT)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50137953(Biphenyl-2-carboxylic acid [2-[4-(4-diethylamino-p...)
Affinity DataIC50:  4nMAssay Description:Inhibitory activity against arginine vasopressin V1 receptor using [3H]AVP as radioligand in rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a/V1b receptor(RAT)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50137940(Biphenyl-2-carboxylic acid [2-[4-(4-dimethylamino-...)
Affinity DataIC50:  6nMAssay Description:Inhibitory activity against arginine vasopressin V1 receptor using [3H]AVP as radioligand in rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a/V1b receptor(RAT)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50291329(8-arginine vasopressin trisulphide | CHEMBL267405)
Affinity DataIC50:  9.5nMAssay Description:Tested for the TYR(Me)2 arginine-vasopressin as radioligand at 0.3 nM in A7r5 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetVasopressin V1a/V1b receptor(RAT)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM35667(AVP | CHEMBL373742 | US10131692, 44 (AVP) | [3H]Ar...)
Affinity DataIC50:  10nMAssay Description:Tested for the TYR(Me)2 arginine-vasopressin as radioligand at 0.3 nM in A7r5 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetVasopressin V1a/V1b receptor(RAT)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50137956(Biphenyl-2-carboxylic acid [2-[4-(4-methyl-piperaz...)
Affinity DataIC50:  20nMAssay Description:Inhibitory activity against arginine vasopressin V1 receptor using [3H]AVP as radioligand in rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a/V1b receptor(RAT)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50137949(Biphenyl-2-carboxylic acid [2-[4-(4-methyl-[1,4]di...)
Affinity DataIC50:  20nMAssay Description:Inhibitory activity against arginine vasopressin V1 receptor using [3H]AVP as radioligand in rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a/V1b receptor(RAT)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50137951(Biphenyl-2-carboxylic acid [2-{4-[(2-dimethylamino...)
Affinity DataIC50:  20nMAssay Description:Inhibitory activity against arginine vasopressin V1 receptor using [3H]AVP as radioligand in rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a/V1b receptor(RAT)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50137946(Biphenyl-2-carboxylic acid [2-[2-(4-dimethylamino-...)
Affinity DataIC50:  20nMAssay Description:Inhibitory activity against arginine vasopressin V1 receptor using [3H]AVP as radioligand in rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a/V1b receptor(RAT)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50137942(Biphenyl-2-carboxylic acid [2-(4-[1,4']bipiperidin...)
Affinity DataIC50:  20nMAssay Description:Inhibitory activity against arginine vasopressin V1 receptor using [3H]AVP as radioligand in rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a/V1b receptor(RAT)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50043204(1N-[2-hydroxy-7,7-dimethyl-1-spiro[1H-indene-1,4'-...)
Affinity DataIC50:  67nMAssay Description:Inhibition of radioligand [3H]AVP binding to the vasopressin V1 receptor in rat liver tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a/V1b receptor(RAT)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50043080(3-[7,7-dimethyl-1-spiro[2,3-dihydro-1H-indene-1,4'...)
Affinity DataIC50:  110nMAssay Description:Inhibition of radioligand [3H]AVP binding to the vasopressin V1 receptor in rat liver tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a/V1b receptor(RAT)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50043141(5-(3-amino-1H-1,2,4-triazol-5-ylaminomethyl)-3-[7,...)
Affinity DataIC50:  120nMAssay Description:Inhibition of radioligand [3H]AVP binding to the vasopressin V1 receptor in rat liver tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a/V1b receptor(RAT)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50043114(3-{1-[7,7-dimethyl-1-spiro[2,3-dihydro-1H-indene-1...)
Affinity DataIC50:  160nMAssay Description:Inhibition of radioligand [3H]AVP binding to the vasopressin V1 receptor in rat liver tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a/V1b receptor(RAT)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50137943(Biphenyl-2-carboxylic acid (4-{8-[2-(4-methyl-pipe...)
Affinity DataIC50:  200nMAssay Description:Inhibitory activity against arginine vasopressin V1 receptor using [3H]AVP as radioligand in rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a/V1b receptor(RAT)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50204026(CHEMBL369150)
Affinity DataIC50:  200nMAssay Description:Inhibitory activity against arginine vasopressin V1 receptor using [3H]AVP as radioligand in rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a/V1b receptor(RAT)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50137941(Biphenyl-2-carboxylic acid {4-[8-(2-pyrrolidin-1-y...)
Affinity DataIC50:  200nMAssay Description:Inhibitory activity against arginine vasopressin V1 receptor using [3H]AVP as radioligand in rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a/V1b receptor(RAT)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50043180(1N-[2-hydroxy-7,7-dimethyl-1-spiro[1H-indene-1,4'-...)
Affinity DataIC50:  290nMAssay Description:Inhibition of radioligand [3H]AVP binding to the vasopressin V1 receptor in rat liver tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a/V1b receptor(RAT)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50137954(Biphenyl-2-carboxylic acid {4-[8-(2-dimethylamino-...)
Affinity DataIC50:  300nMAssay Description:Inhibitory activity against arginine vasopressin V1 receptor using [3H]AVP as radioligand in rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a/V1b receptor(RAT)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50043189(1N-[7,7-dimethyl-1-spiro[2,3-dihydro-1H-indene-1,4...)
Affinity DataIC50: >300nMAssay Description:Inhibition of radioligand [3H]AVP binding to the vasopressin V1 receptor in rat liver tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a/V1b receptor(RAT)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50043116(1N-{2-[2-hydroxy-7,7-dimethyl-1-spiro[1H-indene-1,...)
Affinity DataIC50: >300nMAssay Description:Inhibition of radioligand [3H]AVP binding to the vasopressin V1 receptor in rat liver tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a/V1b receptor(RAT)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50043059(1N-[2-hydroxy-7,7-dimethyl-1-spiro[1H-indene-1,4'-...)
Affinity DataIC50: >300nMAssay Description:Inhibition of radioligand [3H]AVP binding to the vasopressin V1 receptor in rat liver tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a/V1b receptor(RAT)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50043145(3N-[2-hydroxy-7,7-dimethyl-1-spiro[1H-indene-1,4'-...)
Affinity DataIC50: >300nMAssay Description:Inhibition of radioligand [3H]AVP binding to the vasopressin V1 receptor in rat liver tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a/V1b receptor(RAT)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50043090(1N-[2-hydroxy-7,7-dimethyl-1-spiro[1H-indene-1,4'-...)
Affinity DataIC50: >300nMAssay Description:Inhibition of radioligand [3H]AVP binding to the vasopressin V1 receptor in rat liver tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a/V1b receptor(RAT)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50043055(2-{3-[7,7-dimethyl-1-spiro[2,3-dihydro-1H-indene-1...)
Affinity DataIC50: >300nMAssay Description:Inhibition of radioligand [3H]AVP binding to the vasopressin V1 receptor in rat liver tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a/V1b receptor(RAT)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50043155(1N-[7,7-dimethyl-1-spiro[2,3-dihydro-1H-indene-1,4...)
Affinity DataIC50: >300nMAssay Description:Inhibition of radioligand [3H]AVP binding to the vasopressin V1 receptor in rat liver tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a/V1b receptor(RAT)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50043106(CHEMBL335886 | methyl 3-[2-hydroxy-7,7-dimethyl-1-...)
Affinity DataIC50: >300nMAssay Description:Inhibition of radioligand [3H]AVP binding to the vasopressin V1 receptor in rat liver tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a/V1b receptor(RAT)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50043075(1N-[7,7-dimethyl-1-spiro[2,3-dihydro-1H-indene-1,4...)
Affinity DataIC50: >300nMAssay Description:Inhibition of radioligand [3H]AVP binding to the vasopressin V1 receptor in rat liver tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a/V1b receptor(RAT)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50043117(1-[7,7-dimethyl-1-spiro[2,3-dihydro-1H-indene-1,4'...)
Affinity DataIC50: >300nMAssay Description:Inhibition of radioligand [3H]AVP binding to the vasopressin V1 receptor in rat liver tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a/V1b receptor(RAT)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50043088(3-[7,7-dimethyl-1-spiro[2,3-dihydro-1H-indene-1,4'...)
Affinity DataIC50: >300nMAssay Description:Inhibition of radioligand [3H]-AVP binding to the vasopressin V2 receptor in rat kidney tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a/V1b receptor(RAT)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50043143(1N-[2-hydroxy-7,7-dimethyl-1-spiro[1H-indene-1,4'-...)
Affinity DataIC50:  310nMAssay Description:Inhibition of radioligand [3H]-AVP binding to the vasopressin V2 receptor in rat kidney tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a/V1b receptor(RAT)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50043120(1N-[7,7-dimethyl-1-spiro[2,3-dihydro-1H-indene-1,4...)
Affinity DataIC50:  320nMAssay Description:Inhibition of radioligand [3H]AVP binding to the vasopressin V1 receptor in rat liver tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a/V1b receptor(RAT)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50043093(3-[7,7-dimethyl-1-spiro[2,3-dihydro-1H-indene-1,4'...)
Affinity DataIC50:  370nMAssay Description:Inhibition of radioligand [3H]AVP binding to the vasopressin V1 receptor in rat liver tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a/V1b receptor(RAT)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50043077(2-{1-[7,7-dimethyl-1-spiro[2,3-dihydro-1H-indene-1...)
Affinity DataIC50:  410nMAssay Description:Inhibition of radioligand [3H]AVP binding to the vasopressin V1 receptor in rat liver tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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