Compile Data Set for Download or QSAR
maximum 50k data
Found 60 Enz. Inhib. hit(s) with all data for entry = 50016685
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50171982(4-[2-(7-Chloro-5-ethyl-10-methyl-11-oxo-10,11-dihy...)
Affinity DataIC50:  10nMpH: 7.8Assay Description:Inhibitory activity of compound dissolved in DMSO was determined against HIV-1 wild type reverse transcriptase (1-2 nM) by using [3H]-dGTP (71 nM) a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50171979(6-[2-(5-Ethyl-10-methyl-11-oxo-10,11-dihydro-5H-4,...)
Affinity DataIC50:  14nMpH: 7.8Assay Description:Inhibitory activity of compound dissolved in DMSO was determined against HIV-1 wild type reverse transcriptase (1-2 nM) by using [3H]-dGTP (71 nM) a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50171976(4-[2-(5-Ethyl-7-fluoro-10-methyl-11-oxo-10,11-dihy...)
Affinity DataIC50:  15nMpH: 7.8Assay Description:Inhibitory activity of compound dissolved in DMSO was determined against HIV-1 wild type reverse transcriptase (1-2 nM) by using [3H]-dGTP (71 nM) a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50171974(4-[2-(5-Ethyl-7-methoxy-10-methyl-11-oxo-10,11-dih...)
Affinity DataIC50:  15nMpH: 7.8Assay Description:Inhibitory activity of compound dissolved in DMSO was determined against HIV-1 wild type reverse transcriptase (1-2 nM) by using [3H]-dGTP (71 nM) a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50171971(4-[2-(5-Ethyl-10-methyl-11-oxo-10,11-dihydro-5H-4,...)
Affinity DataIC50:  17nMpH: 7.8Assay Description:Inhibitory activity of compound dissolved in DMSO was determined against HIV-1 wild type reverse transcriptase (1-2 nM) by using [3H]-dGTP (71 nM) a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50171973(3-Bromo-4-[2-(5-ethyl-10-methyl-11-oxo-10,11-dihyd...)
Affinity DataIC50:  18nMpH: 7.8Assay Description:Inhibitory activity of compound dissolved in DMSO was determined against HIV-1 wild type reverse transcriptase (1-2 nM) by using [3H]-dGTP (71 nM) a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50171980(3-Ethyl-4-[2-(5-ethyl-10-methyl-11-oxo-10,11-dihyd...)
Affinity DataIC50:  19nMpH: 7.8Assay Description:Inhibitory activity of compound dissolved in DMSO was determined against HIV-1 wild type reverse transcriptase (1-2 nM) by using [3H]-dGTP (71 nM) a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50171981(4-[2-(5-Ethyl-7,10-dimethyl-11-oxo-10,11-dihydro-5...)
Affinity DataIC50:  19nMpH: 7.8Assay Description:Inhibitory activity of compound dissolved in DMSO was determined against HIV-1 wild type reverse transcriptase (1-2 nM) by using [3H]-dGTP (71 nM) a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50171975(3-{4-[2-(5-Ethyl-10-methyl-11-oxo-10,11-dihydro-5H...)
Affinity DataIC50:  22nMpH: 7.8Assay Description:Inhibitory activity of compound dissolved in DMSO was determined against HIV-1 wild type reverse transcriptase (1-2 nM) by using [3H]-dGTP (71 nM) a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50171983(CHEMBL370699 | {4-[2-(5-Ethyl-10-methyl-11-oxo-10,...)
Affinity DataIC50:  23nMpH: 7.8Assay Description:Inhibitory activity of compound dissolved in DMSO was determined against HIV-1 wild type reverse transcriptase (1-2 nM) by using [3H]-dGTP (71 nM) a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50171978(4-[2-(5-Ethyl-10-methyl-11-oxo-10,11-dihydro-5H-4,...)
Affinity DataIC50:  27nMpH: 7.8Assay Description:Inhibitory activity of compound dissolved in DMSO was determined against HIV-1 wild type reverse transcriptase (1-2 nM) by using [3H]-dGTP (71 nM) a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50171977(5-[2-(5-Ethyl-10-methyl-11-oxo-10,11-dihydro-5H-4,...)
Affinity DataIC50:  60nMpH: 7.8Assay Description:Inhibitory activity of compound dissolved in DMSO was determined against HIV-1 wild type reverse transcriptase (1-2 nM) by using [3H]-dGTP (71 nM) a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50171984(6-[2-(5-Ethyl-10-methyl-11-oxo-10,11-dihydro-5H-4,...)
Affinity DataIC50:  63nMpH: 7.8Assay Description:Inhibitory activity of compound dissolved in DMSO was determined against HIV-1 wild type reverse transcriptase (1-2 nM) by using [3H]-dGTP (71 nM) a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50171982(4-[2-(7-Chloro-5-ethyl-10-methyl-11-oxo-10,11-dihy...)
Affinity DataIC50:  64nMpH: 7.8Assay Description:Inhibitory activity of compound dissolved in DMSO was determined against HIV-1 (K103N/Y181C) mutant reverse transcriptase (1-2 nM) by using [3H]-dGTP...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50171972(4-[2-(5-Ethyl-10-methyl-11-oxo-10,11-dihydro-5H-4,...)
Affinity DataIC50:  95nMpH: 7.8Assay Description:Inhibitory activity of compound dissolved in DMSO was determined against HIV-1 wild type reverse transcriptase (1-2 nM) by using [3H]-dGTP (71 nM) a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50171976(4-[2-(5-Ethyl-7-fluoro-10-methyl-11-oxo-10,11-dihy...)
Affinity DataIC50:  150nMpH: 7.8Assay Description:Inhibitory activity of compound dissolved in DMSO was determined against HIV-1 (K103N/Y181C) mutant reverse transcriptase (1-2 nM) by using [3H]-dGTP...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50171978(4-[2-(5-Ethyl-10-methyl-11-oxo-10,11-dihydro-5H-4,...)
Affinity DataIC50:  194nMpH: 7.8Assay Description:Inhibitory activity of compound dissolved in DMSO was determined against HIV-1 (K103N/Y181C) mutant reverse transcriptase (1-2 nM) by using [3H]-dGTP...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50171975(3-{4-[2-(5-Ethyl-10-methyl-11-oxo-10,11-dihydro-5H...)
Affinity DataIC50:  200nMpH: 7.8Assay Description:Inhibitory activity of compound dissolved in DMSO was determined against HIV-1 (K103N/Y181C) mutant reverse transcriptase (1-2 nM) by using [3H]-dGTP...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50171971(4-[2-(5-Ethyl-10-methyl-11-oxo-10,11-dihydro-5H-4,...)
Affinity DataIC50:  221nMpH: 7.8Assay Description:Inhibitory activity of compound dissolved in DMSO was determined against HIV-1 (K103N/Y181C) mutant reverse transcriptase (1-2 nM) by using [3H]-dGTP...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50171981(4-[2-(5-Ethyl-7,10-dimethyl-11-oxo-10,11-dihydro-5...)
Affinity DataIC50:  280nMpH: 7.8Assay Description:Inhibitory activity of compound dissolved in DMSO was determined against HIV-1 (K103N/Y181C) mutant reverse transcriptase (1-2 nM) by using [3H]-dGTP...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50171974(4-[2-(5-Ethyl-7-methoxy-10-methyl-11-oxo-10,11-dih...)
Affinity DataIC50:  300nMpH: 7.8Assay Description:Inhibitory activity of compound dissolved in DMSO was determined against HIV-1 (K103N/Y181C) mutant reverse transcriptase (1-2 nM) by using [3H]-dGTP...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50171973(3-Bromo-4-[2-(5-ethyl-10-methyl-11-oxo-10,11-dihyd...)
Affinity DataIC50:  300nMpH: 7.8Assay Description:Inhibitory activity of compound dissolved in DMSO was determined against HIV-1 (K103N/Y181C) mutant reverse transcriptase (1-2 nM) by using [3H]-dGTP...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50171983(CHEMBL370699 | {4-[2-(5-Ethyl-10-methyl-11-oxo-10,...)
Affinity DataIC50:  370nMpH: 7.8Assay Description:Inhibitory activity of compound dissolved in DMSO was determined against HIV-1 (K103N/Y181C) mutant reverse transcriptase (1-2 nM) by using [3H]-dGTP...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50171980(3-Ethyl-4-[2-(5-ethyl-10-methyl-11-oxo-10,11-dihyd...)
Affinity DataIC50:  430nMpH: 7.8Assay Description:Inhibitory activity of compound dissolved in DMSO was determined against HIV-1 (K103N/Y181C) mutant reverse transcriptase (1-2 nM) by using [3H]-dGTP...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50171977(5-[2-(5-Ethyl-10-methyl-11-oxo-10,11-dihydro-5H-4,...)
Affinity DataIC50:  550nMpH: 7.8Assay Description:Inhibitory activity of compound dissolved in DMSO was determined against HIV-1 (K103N/Y181C) mutant reverse transcriptase (1-2 nM) by using [3H]-dGTP...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50171979(6-[2-(5-Ethyl-10-methyl-11-oxo-10,11-dihydro-5H-4,...)
Affinity DataIC50:  1.10E+3nMpH: 7.8Assay Description:Inhibitory activity of compound dissolved in DMSO was determined against HIV-1 (K103N/Y181C) mutant reverse transcriptase (1-2 nM) by using [3H]-dGTP...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50171971(4-[2-(5-Ethyl-10-methyl-11-oxo-10,11-dihydro-5H-4,...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibitory concentration (1.5 mM) against human CYP450 2C19 dissolved in acetonitrile/methanolMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50171976(4-[2-(5-Ethyl-7-fluoro-10-methyl-11-oxo-10,11-dihy...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibitory concentration (1.5 mM) against human CYP450 2C19 dissolved in acetonitrile/methanolMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50171984(6-[2-(5-Ethyl-10-methyl-11-oxo-10,11-dihydro-5H-4,...)
Affinity DataIC50:  4.00E+3nMpH: 7.8Assay Description:Inhibitory activity of compound dissolved in DMSO was determined against HIV-1 (K103N/Y181C) mutant reverse transcriptase (1-2 nM) by using [3H]-dGTP...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50171972(4-[2-(5-Ethyl-10-methyl-11-oxo-10,11-dihydro-5H-4,...)
Affinity DataIC50:  4.48E+3nMpH: 7.8Assay Description:Inhibitory activity of compound dissolved in DMSO was determined against HIV-1 (K103N/Y181C) mutant reverse transcriptase (1-2 nM) by using [3H]-dGTP...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50171976(4-[2-(5-Ethyl-7-fluoro-10-methyl-11-oxo-10,11-dihy...)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibitory concentration (1.5 mM) against human CYP450 2C9 dissolved in acetonitrile/methanolMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50171971(4-[2-(5-Ethyl-10-methyl-11-oxo-10,11-dihydro-5H-4,...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibitory concentration (1.5 mM) against human CYP450 2C9 dissolved in acetonitrile/methanolMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50171976(4-[2-(5-Ethyl-7-fluoro-10-methyl-11-oxo-10,11-dihy...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibitory concentration (1.5 mM) against human CYP450 3A4 dissolved in acetonitrile/methanol using 7-Benzyloxy-4-(trifluoromethyl)coumarin (BFC) as ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50171976(4-[2-(5-Ethyl-7-fluoro-10-methyl-11-oxo-10,11-dihy...)
Affinity DataIC50:  1.90E+4nMAssay Description:Inhibitory concentration (1.5 mM) against human CYP450 1A2 dissolved in acetonitrile/methanolMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50171971(4-[2-(5-Ethyl-10-methyl-11-oxo-10,11-dihydro-5H-4,...)
Affinity DataIC50:  2.40E+4nMAssay Description:Inhibitory concentration (1.5 mM) against human CYP450 3A4 dissolved in acetonitrile/methanol using 7-Benzyloxy-4-(trifluoromethyl)coumarin (BFC) as ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50171971(4-[2-(5-Ethyl-10-methyl-11-oxo-10,11-dihydro-5H-4,...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibitory concentration (1.5 mM) against human CYP450 3A4 dissolved in acetonitrile/methanol using 7-Benzyloxy-quinoline (BQ) as fluorogenic substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50171971(4-[2-(5-Ethyl-10-methyl-11-oxo-10,11-dihydro-5H-4,...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibitory concentration (1.5 mM) against human CYP450 2D6 dissolved in acetonitrile/methanolMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50171976(4-[2-(5-Ethyl-7-fluoro-10-methyl-11-oxo-10,11-dihy...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibitory concentration (1.5 mM) against human CYP450 2D6 dissolved in acetonitrile/methanolMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50171971(4-[2-(5-Ethyl-10-methyl-11-oxo-10,11-dihydro-5H-4,...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibitory concentration (1.5 mM) against human CYP450 1A2 dissolved in acetonitrile/methanolMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50171976(4-[2-(5-Ethyl-7-fluoro-10-methyl-11-oxo-10,11-dihy...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibitory concentration (1.5 mM) against human CYP450 3A4 dissolved in acetonitrile/methanol using 7-Benzyloxy-quinoline (BQ) as fluorogenic substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50171973(3-Bromo-4-[2-(5-ethyl-10-methyl-11-oxo-10,11-dihyd...)
Affinity DataEC50:  35nMAssay Description:Effective concentration of the compound towards HIV-1 K103N/Y181C mutant reverse transcriptase activity by 50% measured in cellular assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50171982(4-[2-(7-Chloro-5-ethyl-10-methyl-11-oxo-10,11-dihy...)
Affinity DataEC50:  1.60nMAssay Description:Effective concentration towards HIV-1 wild type reverse transcriptase activity by 50% measured in cellular assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50171974(4-[2-(5-Ethyl-7-methoxy-10-methyl-11-oxo-10,11-dih...)
Affinity DataEC50:  1.90nMAssay Description:Effective concentration towards HIV-1 wild type reverse transcriptase activity by 50% measured in cellular assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50171980(3-Ethyl-4-[2-(5-ethyl-10-methyl-11-oxo-10,11-dihyd...)
Affinity DataEC50:  2.20nMAssay Description:Effective concentration towards HIV-1 wild type reverse transcriptase activity by 50% measured in cellular assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50171981(4-[2-(5-Ethyl-7,10-dimethyl-11-oxo-10,11-dihydro-5...)
Affinity DataEC50:  1.30nMAssay Description:Effective concentration towards HIV-1 wild type reverse transcriptase activity by 50% measured in cellular assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50171983(CHEMBL370699 | {4-[2-(5-Ethyl-10-methyl-11-oxo-10,...)
Affinity DataEC50:  139nMAssay Description:Effective concentration of the compound towards HIV-1 K103N/Y181C mutant reverse transcriptase activity by 50% measured in cellular assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50171976(4-[2-(5-Ethyl-7-fluoro-10-methyl-11-oxo-10,11-dihy...)
Affinity DataEC50:  14nMAssay Description:Effective concentration of the compound towards HIV-1 K103N/Y181C mutant reverse transcriptase activity by 50% measured in cellular assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50171972(4-[2-(5-Ethyl-10-methyl-11-oxo-10,11-dihydro-5H-4,...)
Affinity DataEC50:  3.30nMAssay Description:Effective concentration towards HIV-1 wild type reverse transcriptase activity by 50% measured in cellular assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50171982(4-[2-(7-Chloro-5-ethyl-10-methyl-11-oxo-10,11-dihy...)
Affinity DataEC50:  8.10nMAssay Description:Effective concentration of the compound towards HIV-1 K103N/Y181C mutant reverse transcriptase activity by 50% measured in cellular assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50171973(3-Bromo-4-[2-(5-ethyl-10-methyl-11-oxo-10,11-dihyd...)
Affinity DataEC50:  3.20nMAssay Description:Effective concentration towards HIV-1 wild type reverse transcriptase activity by 50% measured in cellular assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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