Compile Data Set for Download or QSAR
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Found 28 Enz. Inhib. hit(s) with all data for entry = 50011496
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Università

Curated by ChEMBL
LigandPNGBDBM16314(2-{[6-methoxy-5-(trifluoromethyl)naphthalen-1-yl]-...)
Affinity DataIC50:  50nMAssay Description:Inhibitory concentration to aldose reductase (ALR-2) obtained from rat lensMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Università

Curated by ChEMBL
LigandPNGBDBM50107141((10-Benzyl-3,4-dioxo-3,4-dihydro-10H-benzo[4,5]imi...)
Affinity DataIC50:  360nMAssay Description:Inhibitory concentration to aldose reductase (ALR-2) obtained from rat lensMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Università

Curated by ChEMBL
LigandPNGBDBM16312((4S)-6-fluoro-2,3-dihydrospiro[1-benzopyran-4,4'-i...)
Affinity DataIC50:  650nMAssay Description:Inhibitory concentration to aldose reductase (ALR-2) obtained from rat lensMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Università

Curated by ChEMBL
LigandPNGBDBM50107134(CHEMBL136855 | [2-(Carboxymethyl-hydrazono)-3-(4-t...)
Affinity DataIC50:  2.63E+3nMAssay Description:Inhibitory concentration to aldose reductase (ALR-2) obtained from rat lensMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Università

Curated by ChEMBL
LigandPNGBDBM50107153(CHEMBL334916 | [10-(4-Chloro-benzyl)-3,4-dioxo-3,4...)
Affinity DataIC50:  4.15E+3nMAssay Description:Inhibitory concentration to aldose reductase (ALR-2) obtained from rat lensMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Università

Curated by ChEMBL
LigandPNGBDBM50107139(CHEMBL134308 | [10-(3,4-Difluoro-benzyl)-3,4-dioxo...)
Affinity DataIC50:  4.42E+3nMAssay Description:Inhibitory concentration to aldose reductase (ALR-2) obtained from rat lensMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Università

Curated by ChEMBL
LigandPNGBDBM50107135(CHEMBL136825 | [10-(4-Bromo-2-fluoro-benzyl)-3,4-d...)
Affinity DataIC50:  4.47E+3nMAssay Description:Inhibitory concentration to aldose reductase (ALR-2) obtained from rat lensMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Università

Curated by ChEMBL
LigandPNGBDBM50107158(CHEMBL136452 | [3-Benzyl-2-(carboxymethyl-hydrazon...)
Affinity DataIC50:  4.50E+3nMAssay Description:Inhibitory concentration to aldose reductase (ALR-2) obtained from rat lensMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Università

Curated by ChEMBL
LigandPNGBDBM50107142(CHEMBL136723 | [10-(4-Fluoro-benzyl)-3,4-dioxo-3,4...)
Affinity DataIC50:  4.58E+3nMAssay Description:Inhibitory concentration to aldose reductase (ALR-2) obtained from rat lensMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Università

Curated by ChEMBL
LigandPNGBDBM50107146((10-Benzyl-4-oxo-4,10-dihydro-benzo[4,5]imidazo[2,...)
Affinity DataIC50:  5.44E+3nMAssay Description:Inhibitory concentration to aldose reductase (ALR-2) obtained from rat lensMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Università

Curated by ChEMBL
LigandPNGBDBM7460(2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-4H-chrome...)
Affinity DataIC50:  7.81E+3nMAssay Description:Inhibitory concentration to aldose reductase (ALR-2) obtained from rat lensMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Università

Curated by ChEMBL
LigandPNGBDBM50107154(CHEMBL335578 | [2-(Carboxymethyl-hydrazono)-3-(3,4...)
Affinity DataIC50:  9.72E+3nMAssay Description:Inhibitory concentration to aldose reductase (ALR-2) obtained from rat lensMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Università

Curated by ChEMBL
LigandPNGBDBM50107145(CHEMBL135144 | [2-(Carboxymethyl-hydrazono)-3-(4-c...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibitory concentration to aldose reductase (ALR-2) obtained from rat lensMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Università

Curated by ChEMBL
LigandPNGBDBM50107155(CHEMBL136157 | [3-(4-Bromo-2-fluoro-benzyl)-2-(car...)
Affinity DataIC50:  1.25E+4nMAssay Description:Inhibitory concentration to aldose reductase (ALR-2) obtained from rat lensMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Università

Curated by ChEMBL
LigandPNGBDBM50107150(CHEMBL136884 | [10-(4-Methyl-benzyl)-3,4-dioxo-3,4...)
Affinity DataIC50:  1.33E+4nMAssay Description:Inhibitory concentration to aldose reductase (ALR-2) obtained from rat lensMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Università

Curated by ChEMBL
LigandPNGBDBM50107138((10-Carboxymethyl-3,4-dioxo-3,4-dihydro-10H-benzo[...)
Affinity DataIC50:  1.35E+4nMAssay Description:Inhibitory concentration to aldose reductase (ALR-2) obtained from rat lensMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Università

Curated by ChEMBL
LigandPNGBDBM50107140(CHEMBL343594 | [2-(Carboxymethyl-hydrazono)-3-(4-f...)
Affinity DataIC50:  1.48E+4nMAssay Description:Inhibitory concentration to aldose reductase (ALR-2) obtained from rat lensMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Università

Curated by ChEMBL
LigandPNGBDBM50107143((10-Methyl-4-oxo-4,10-dihydro-benzo[4,5]imidazo[2,...)
Affinity DataIC50:  1.70E+4nMAssay Description:Inhibitory concentration to aldose reductase (ALR-2) obtained from rat lensMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Università

Curated by ChEMBL
LigandPNGBDBM50107156(CHEMBL137661 | [3,4-Dioxo-10-(4-trifluoromethyl-be...)
Affinity DataIC50:  2.39E+4nMAssay Description:Inhibitory concentration to aldose reductase (ALR-2) obtained from rat lensMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Università

Curated by ChEMBL
LigandPNGBDBM50107151((10-Methyl-3,4-dioxo-3,4-dihydro-10H-benzo[4,5]imi...)
Affinity DataIC50:  2.48E+4nMAssay Description:Inhibitory concentration to aldose reductase (ALR-2) obtained from rat lensMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Università

Curated by ChEMBL
LigandPNGBDBM50107137((4-Oxo-4,10-dihydro-benzo[4,5]imidazo[2,1-c][1,2,4...)
Affinity DataIC50:  3.59E+4nMAssay Description:Inhibitory concentration to aldose reductase (ALR-2) obtained from rat lensMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Università

Curated by ChEMBL
LigandPNGBDBM50107149((3,4-Dioxo-10-propyl-3,4-dihydro-10H-benzo[4,5]imi...)
Affinity DataIC50:  3.72E+4nMAssay Description:Inhibitory concentration to aldose reductase (ALR-2) obtained from rat lensMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Università

Curated by ChEMBL
LigandPNGBDBM50107144(CHEMBL335729 | [10-(4-Methoxy-benzyl)-3,4-dioxo-3,...)
Affinity DataIC50:  4.26E+4nMAssay Description:Inhibitory concentration to aldose reductase (ALR-2) obtained from rat lensMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Università

Curated by ChEMBL
LigandPNGBDBM50107157(CHEMBL136083 | [2-(Carboxymethyl-hydrazono)-3-(4-m...)
Affinity DataIC50:  4.45E+4nMAssay Description:Inhibitory concentration to aldose reductase (ALR-2) obtained from rat lensMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Università

Curated by ChEMBL
LigandPNGBDBM50107147(CHEMBL434229 | [2-(Carboxymethyl-hydrazono)-3-(4-m...)
Affinity DataIC50:  4.59E+4nMAssay Description:Inhibitory concentration to aldose reductase (ALR-2) obtained from rat lensMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Università

Curated by ChEMBL
LigandPNGBDBM50107148(CHEMBL434249 | [2-(Carboxymethyl-hydrazono)-3-prop...)
Affinity DataIC50:  4.65E+4nMAssay Description:Inhibitory concentration to aldose reductase (ALR-2) obtained from rat lensMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Università

Curated by ChEMBL
LigandPNGBDBM50107152(CHEMBL136285 | [2-(Carboxymethyl-hydrazono)-3-meth...)
Affinity DataIC50:  1.09E+5nMAssay Description:Inhibitory concentration to aldose reductase (ALR-2) obtained from rat lensMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Università

Curated by ChEMBL
LigandPNGBDBM50107136(CHEMBL336224 | [3-Carboxymethyl-2-(carboxymethyl-h...)
Affinity DataIC50:  2.36E+5nMAssay Description:Inhibitory concentration to aldose reductase (ALR-2) obtained from rat lensMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed