Compile Data Set for Download or QSAR
maximum 50k data
Found 185 Enz. Inhib. hit(s) with all data for entry = 50011965
TargetEndothelin-1 receptor(RAT)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50112678((R)-2-Benzo[1,3]dioxol-5-yl-6-isopropoxy-4-(4-meth...)
Affinity DataIC50:  0.190nMAssay Description:Binding affinity for endothelin A receptor by inhibition of [125I]-ET-1 binding in rat aorta smooth muscle cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50112738(2-Benzo[1,3]dioxol-5-yl-6-isopropoxy-4-(4-methoxy-...)
Affinity DataIC50:  0.210nMAssay Description:Binding affinity for endothelin A receptor by inhibition of [125I]-ET-1 binding in rat aorta smooth muscle cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50112662(2-Benzo[1,3]dioxol-5-yl-4-butylsulfanyl-6-isopropo...)
Affinity DataIC50:  0.270nMAssay Description:Binding affinity for endothelin A receptor by inhibition of [125I]-ET-1 binding in rat aorta smooth muscle cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50112694(2-Benzo[1,3]dioxol-5-yl-6-isopropoxy-4-pentyl-2H-c...)
Affinity DataIC50:  0.320nMAssay Description:Binding affinity for endothelin A receptor by inhibition of [125I]-ET-1 binding in rat aorta smooth muscle cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50112667(2-Benzo[1,3]dioxol-5-yl-6-isopropoxy-4-pent-4-enyl...)
Affinity DataIC50:  0.330nMAssay Description:Binding affinity for endothelin A receptor by inhibition of [125I]-ET-1 binding in rat aorta smooth muscle cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50112660(2-Benzo[1,3]dioxol-5-yl-4-butoxy-6-isopropoxy-2H-c...)
Affinity DataIC50:  0.410nMAssay Description:Binding affinity for endothelin A receptor by inhibition of [125I]-ET-1 binding in rat aorta smooth muscle cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50112748((R)-2-Benzo[1,3]dioxol-5-yl-4-butyl-6-isopropoxy-2...)
Affinity DataIC50:  0.420nMAssay Description:Binding affinity for endothelin A receptor by inhibition of [125I]-ET-1 binding in rat aorta smooth muscle cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50112678((R)-2-Benzo[1,3]dioxol-5-yl-6-isopropoxy-4-(4-meth...)
Affinity DataIC50:  0.450nMAssay Description:Binding affinity at human Endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50112751(2-Benzo[1,3]dioxol-5-yl-6-isopropoxy-4-pentyloxy-2...)
Affinity DataIC50:  0.480nMAssay Description:Binding affinity for endothelin A receptor by inhibition of [125I]-ET-1 binding in rat aorta smooth muscle cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50112666(2-Benzo[1,3]dioxol-5-yl-6-isopropoxy-4-(4-methoxy-...)
Affinity DataIC50:  0.510nMAssay Description:Binding affinity for endothelin A receptor by inhibition of [125I]-ET-1 binding in rat aorta smooth muscle cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50112700(2-Benzo[1,3]dioxol-5-yl-6-isopropoxy-4-(4-methoxy-...)
Affinity DataIC50:  0.520nMAssay Description:Binding affinity for endothelin A receptor by inhibition of [125I]-ET-1 binding in rat aorta smooth muscle cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50112675(2-Benzo[1,3]dioxol-5-yl-4-cyclopentyl-6-isopropoxy...)
Affinity DataIC50:  0.530nMAssay Description:Binding affinity for endothelin A receptor by inhibition of [125I]-ET-1 binding in rat aorta smooth muscle cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50112725(2-Benzo[1,3]dioxol-5-yl-4-cyclohexylmethyl-6-isopr...)
Affinity DataIC50:  0.580nMAssay Description:Binding affinity for endothelin A receptor by inhibition of [125I]-ET-1 binding in rat aorta smooth muscle cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50112737(2-Benzo[1,3]dioxol-5-yl-4-hexyl-6-isopropoxy-2H-ch...)
Affinity DataIC50:  0.620nMAssay Description:Binding affinity for endothelin A receptor by inhibition of [125I]-ET-1 binding in rat aorta smooth muscle cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50112732(2-Benzo[1,3]dioxol-5-yl-6-isopropoxy-4-isopropyl-2...)
Affinity DataIC50:  0.630nMAssay Description:Binding affinity for endothelin A receptor by inhibition of [125I]-ET-1 binding in rat aorta smooth muscle cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50112663(2-Benzo[1,3]dioxol-5-yl-4-hexyloxy-6-isopropoxy-2H...)
Affinity DataIC50:  0.670nMAssay Description:Binding affinity for endothelin A receptor by inhibition of [125I]-ET-1 binding in rat aorta smooth muscle cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50112691(2-Benzo[1,3]dioxol-5-yl-4-butyl-6-isopropoxy-2H-ch...)
Affinity DataIC50:  0.730nMAssay Description:Binding affinity for endothelin A receptor by inhibition of [125I]-ET-1 binding in rat aorta smooth muscle cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50112682(2-Benzo[1,3]dioxol-5-yl-4,6-diisopropoxy-2H-chrome...)
Affinity DataIC50:  0.810nMAssay Description:Binding affinity for endothelin A receptor by inhibition of [125I]-ET-1 binding in rat aorta smooth muscle cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50112720(2-Benzo[1,3]dioxol-5-yl-4-(5-hydroxy-pentyloxy)-6-...)
Affinity DataIC50:  0.950nMAssay Description:Binding affinity for endothelin A receptor by inhibition of [125I]-ET-1 binding in rat aorta smooth muscle cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50112718(2-Benzo[1,3]dioxol-5-yl-6-isopropoxy-4-(5-methyl-t...)
Affinity DataIC50:  1nMAssay Description:Binding affinity for endothelin A receptor by inhibition of [125I]-ET-1 binding in rat aorta smooth muscle cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50112661((2S,3S,4R)-2-Benzo[1,3]dioxol-5-yl-6-isopropoxy-4-...)
Affinity DataIC50:  1.30nMAssay Description:Binding affinity for endothelin A receptor by inhibition of [125I]-ET-1 binding in rat aorta smooth muscle cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50112736(2-Benzo[1,3]dioxol-5-yl-6-isopropoxy-4-propoxy-2H-...)
Affinity DataIC50:  1.5nMAssay Description:Binding affinity for endothelin A receptor by inhibition of [125I]-ET-1 binding in rat aorta smooth muscle cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50112669(2-Benzo[1,3]dioxol-5-yl-6-isopropoxy-4-(3-methoxy-...)
Affinity DataIC50:  1.60nMAssay Description:Binding affinity for endothelin A receptor by inhibition of [125I]-ET-1 binding in rat aorta smooth muscle cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50112727(2-Benzo[1,3]dioxol-5-yl-6-isopropoxy-4-(3-methoxy-...)
Affinity DataIC50:  1.80nMAssay Description:Binding affinity for endothelin A receptor by inhibition of [125I]-ET-1 binding in rat aorta smooth muscle cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50112715(CHEMBL62578 | N-[2-Benzo[1,3]dioxol-5-yl-6-isoprop...)
Affinity DataIC50:  1.80nMAssay Description:Binding affinity for endothelin A receptor by inhibition of [125I]-ET-1 binding in rat aorta smooth muscle cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50112745(2-Benzo[1,3]dioxol-5-yl-6-isopropoxy-4-(3-methyl-b...)
Affinity DataIC50:  1.90nMAssay Description:Binding affinity for endothelin A receptor by inhibition of [125I]-ET-1 binding in rat aorta smooth muscle cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50112698(2-Benzo[1,3]dioxol-5-yl-4-butoxy-6-propoxy-2H-chro...)
Affinity DataIC50:  2nMAssay Description:Binding affinity for endothelin A receptor by inhibition of [125I]-ET-1 binding in rat aorta smooth muscle cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50112685(2-Benzo[1,3]dioxol-5-yl-4-ethoxy-6-isopropoxy-2H-c...)
Affinity DataIC50:  2.20nMAssay Description:Binding affinity for endothelin A receptor by inhibition of [125I]-ET-1 binding in rat aorta smooth muscle cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50112696(2-Benzo[1,3]dioxol-5-yl-4-(4-hydroxy-butyl)-6-isop...)
Affinity DataIC50:  2.30nMAssay Description:Binding affinity for endothelin A receptor by inhibition of [125I]-ET-1 binding in rat aorta smooth muscle cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50112710(2-Benzo[1,3]dioxol-5-yl-6-(2-hydroxy-1-methyl-etho...)
Affinity DataIC50:  2.80nMAssay Description:Binding affinity for endothelin A receptor by inhibition of [125I]-ET-1 binding in rat aorta smooth muscle cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50112689(2-Benzo[1,3]dioxol-5-yl-6-isopropoxy-4-phenyl-2H-c...)
Affinity DataIC50:  3nMAssay Description:Binding affinity for endothelin A receptor by inhibition of [125I]-ET-1 binding in rat aorta smooth muscle cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50112684(2-Benzo[1,3]dioxol-5-yl-6-isopropoxy-4-(2-methoxy-...)
Affinity DataIC50:  3nMAssay Description:Binding affinity for endothelin A receptor by inhibition of [125I]-ET-1 binding in rat aorta smooth muscle cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50112729(2-Benzo[1,3]dioxol-5-yl-6-isopropoxy-4-[2-(4-metho...)
Affinity DataIC50:  3nMAssay Description:Binding affinity for endothelin A receptor by inhibition of [125I]-ET-1 binding in rat aorta smooth muscle cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50112705(2-Benzo[1,3]dioxol-5-yl-4,6-dibutoxy-2H-chromene-3...)
Affinity DataIC50:  3nMAssay Description:Binding affinity for endothelin A receptor by inhibition of [125I]-ET-1 binding in rat aorta smooth muscle cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50112690(2,4-Bis-benzo[1,3]dioxol-5-yl-6-isopropoxy-2H-chro...)
Affinity DataIC50:  3.20nMAssay Description:Binding affinity for endothelin A receptor by inhibition of [125I]-ET-1 binding in rat aorta smooth muscle cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50112692(2-Benzo[1,3]dioxol-5-yl-6-ethoxy-4-(4-methoxy-phen...)
Affinity DataIC50:  3.80nMAssay Description:Binding affinity for endothelin A receptor by inhibition of [125I]-ET-1 binding in rat aorta smooth muscle cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50112740(2-Benzo[1,3]dioxol-5-yl-4-(4-hydroxy-phenyl)-6-iso...)
Affinity DataIC50:  4.10nMAssay Description:Binding affinity for endothelin A receptor by inhibition of [125I]-ET-1 binding in rat aorta smooth muscle cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50112668(2-Benzo[1,3]dioxol-5-yl-4-butoxy-6-ethoxy-2H-chrom...)
Affinity DataIC50:  4.20nMAssay Description:Binding affinity for endothelin A receptor by inhibition of [125I]-ET-1 binding in rat aorta smooth muscle cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50112741(2-Benzo[1,3]dioxol-5-yl-4-(4-methoxy-phenyl)-6-pro...)
Affinity DataIC50:  4.40nMAssay Description:Binding affinity for endothelin A receptor by inhibition of [125I]-ET-1 binding in rat aorta smooth muscle cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50112665(2-Benzo[1,3]dioxol-5-yl-4-heptyloxy-6-isopropoxy-2...)
Affinity DataIC50:  4.70nMAssay Description:Binding affinity for endothelin A receptor by inhibition of [125I]-ET-1 binding in rat aorta smooth muscle cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50112733(2-Benzo[1,3]dioxol-5-yl-6-isopropoxy-4-(4-isopropy...)
Affinity DataIC50:  4.90nMAssay Description:Binding affinity for endothelin A receptor by inhibition of [125I]-ET-1 binding in rat aorta smooth muscle cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50112702(2-Benzo[1,3]dioxol-5-yl-6-isopropoxy-4-methoxy-2H-...)
Affinity DataIC50:  5.20nMAssay Description:Binding affinity for endothelin A receptor by inhibition of [125I]-ET-1 binding in rat aorta smooth muscle cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50112739(2-Benzo[1,3]dioxol-5-yl-4-(4-benzyloxy-phenyl)-6-i...)
Affinity DataIC50:  6.30nMAssay Description:Binding affinity for endothelin A receptor by inhibition of [125I]-ET-1 binding in rat aorta smooth muscle cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50112670(2-Benzo[1,3]dioxol-5-yl-4-(3-cyano-propoxy)-6-isop...)
Affinity DataIC50:  6.80nMAssay Description:Binding affinity for endothelin A receptor by inhibition of [125I]-ET-1 binding in rat aorta smooth muscle cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50112706(2-Benzo[1,3]dioxol-5-yl-4-(4-fluoro-phenyl)-6-isop...)
Affinity DataIC50:  8nMAssay Description:Binding affinity for endothelin A receptor by inhibition of [125I]-ET-1 binding in rat aorta smooth muscle cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50112724(2-(2,4-Dimethoxy-phenyl)-6-isopropoxy-4-(4-methoxy...)
Affinity DataIC50:  8nMAssay Description:Binding affinity for endothelin A receptor by inhibition of [125I]-ET-1 binding in rat aorta smooth muscle cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50112735(2-Benzo[1,3]dioxol-5-yl-6-isopropoxy-4-methoxy-2H-...)
Affinity DataIC50:  9.10nMAssay Description:Binding affinity for endothelin A receptor by inhibition of [125I]-ET-1 binding in rat aorta smooth muscle cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50112704(2-Benzo[1,3]dioxol-5-yl-4-chloro-6-isopropoxy-2H-c...)
Affinity DataIC50:  12nMAssay Description:Binding affinity for endothelin A receptor by inhibition of [125I]-ET-1 binding in rat aorta smooth muscle cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50112697((S)-2-Benzo[1,3]dioxol-5-yl-6-isopropoxy-4-(4-meth...)
Affinity DataIC50:  15nMAssay Description:Binding affinity for endothelin A receptor by inhibition of [125I]-ET-1 binding in rat aorta smooth muscle cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50112744(2-Benzo[1,3]dioxol-5-yl-6-butoxy-4-(4-methoxy-phen...)
Affinity DataIC50:  17nMAssay Description:Binding affinity for endothelin A receptor by inhibition of [125I]-ET-1 binding in rat aorta smooth muscle cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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