Compile Data Set for Download or QSAR
maximum 50k data
Found 40 Enz. Inhib. hit(s) with all data for entry = 50018098
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Hopital Saint-Louis

Curated by ChEMBL
LigandPNGBDBM50191171(2-(4-flurophenyl)-1,10b-dihydro-benzo[e]pyrazolo[1...)
Affinity DataIC50:  1.80nMAssay Description:Activity at 5HT2B receptor expressed in CHO cell assessed as inhibition of alpha-methyl-5HT-stimulated calcium releaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Hopital Saint-Louis

Curated by ChEMBL
LigandPNGBDBM50191182(1-propyl-4'-(pyridin-4-yl)-8'-oxa-5',6'-diazaspiro...)
Affinity DataIC50:  15nMAssay Description:Activity at 5HT2B receptor expressed in CHO cell assessed as inhibition of alpha-methyl-5HT-stimulated calcium releaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Hopital Saint-Louis

Curated by ChEMBL
LigandPNGBDBM50191179(1-(2-phenylethyl)-4'-(pyridin-4-yl)-8'-oxa-5',6'-d...)
Affinity DataIC50:  16nMAssay Description:Activity at 5HT2B receptor expressed in CHO cell assessed as inhibition of alpha-methyl-5HT-stimulated calcium releaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Hopital Saint-Louis

Curated by ChEMBL
LigandPNGBDBM50191173(1-(2-methylpropyl)-4'-(pyridin-4-yl)-8'-oxa-5',6'-...)
Affinity DataIC50:  21nMAssay Description:Activity at 5HT2B receptor expressed in CHO cell assessed as inhibition of alpha-methyl-5HT-stimulated calcium releaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Hopital Saint-Louis

Curated by ChEMBL
LigandPNGBDBM50191181(12'-fluoro-4'-(4-fluorophenyl)-1-propyl-8'-oxa-5',...)
Affinity DataIC50:  26nMAssay Description:Activity at 5HT2B receptor expressed in CHO cell assessed as inhibition of alpha-methyl-5HT-stimulated calcium releaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Hopital Saint-Louis

Curated by ChEMBL
LigandPNGBDBM50191208(12'-bromo-4'-(4-fluorophenyl)-1-propyl-8'-oxa-5',6...)
Affinity DataIC50:  29nMAssay Description:Activity at 5HT2B receptor expressed in CHO cell assessed as inhibition of alpha-methyl-5HT-stimulated calcium releaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Hopital Saint-Louis

Curated by ChEMBL
LigandPNGBDBM50191194(12'-bromo-4'-(4-fluorophenyl)-1-methyl-8'-oxa-5',6...)
Affinity DataIC50:  30nMAssay Description:Activity at 5HT2B receptor expressed in CHO cell assessed as inhibition of alpha-methyl-5HT-stimulated calcium releaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Hopital Saint-Louis

Curated by ChEMBL
LigandPNGBDBM50191191(12'-chloro-4'-(4-fluorophenyl)-1-propyl-8'-oxa-5',...)
Affinity DataIC50:  32nMAssay Description:Activity at 5HT2B receptor expressed in CHO cell assessed as inhibition of alpha-methyl-5HT-stimulated calcium releaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Hopital Saint-Louis

Curated by ChEMBL
LigandPNGBDBM50191196(1-ethyl-4'-(pyridin-4-yl)-8'-oxa-5',6'-diazaspiro[...)
Affinity DataIC50:  42nMAssay Description:Activity at 5HT2B receptor expressed in CHO cell assessed as inhibition of alpha-methyl-5HT-stimulated calcium releaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Hopital Saint-Louis

Curated by ChEMBL
LigandPNGBDBM50191209(4'-(4-fluorophenyl)-10'-methoxy-1-methyl-8'-oxa-5'...)
Affinity DataIC50:  46nMAssay Description:Activity at 5HT2B receptor expressed in CHO cell assessed as inhibition of alpha-methyl-5HT-stimulated calcium releaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Hopital Saint-Louis

Curated by ChEMBL
LigandPNGBDBM50191188(1-methyl-4'-phenyl-8'-oxa-5',6'-diazaspiro[piperid...)
Affinity DataIC50:  50nMAssay Description:Activity at 5HT2B receptor expressed in CHO cell assessed as inhibition of alpha-methyl-5HT-stimulated calcium releaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Hopital Saint-Louis

Curated by ChEMBL
LigandPNGBDBM50191178(12'-bromo-1-methyl-4'-phenyl-8'-oxa-5',6'-diazaspi...)
Affinity DataIC50:  92nMAssay Description:Activity at 5HT2B receptor expressed in CHO cell assessed as inhibition of alpha-methyl-5HT-stimulated calcium releaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Hopital Saint-Louis

Curated by ChEMBL
LigandPNGBDBM50191212(1-methyl-4'-(pyridin-4-yl)-8'-oxa-5',6'-diazaspiro...)
Affinity DataIC50:  95nMAssay Description:Activity at 5HT2B receptor expressed in CHO cell assessed as inhibition of alpha-methyl-5HT-stimulated calcium releaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Hopital Saint-Louis

Curated by ChEMBL
LigandPNGBDBM50191187(12'-bromo-4'-(4-chlorophenyl)-1-methyl-8'-oxa-5',6...)
Affinity DataIC50:  100nMAssay Description:Activity at 5HT2B receptor expressed in CHO cell assessed as inhibition of alpha-methyl-5HT-stimulated calcium releaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Hopital Saint-Louis

Curated by ChEMBL
LigandPNGBDBM50191180(4'-(4-fluorophenyl)-12'-methyl-1-propyl-8'-oxa-5',...)
Affinity DataIC50:  115nMAssay Description:Activity at 5HT2B receptor expressed in CHO cell assessed as inhibition of alpha-methyl-5HT-stimulated calcium releaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Hopital Saint-Louis

Curated by ChEMBL
LigandPNGBDBM50191175(4'-(4-chlorophenyl)-1-(propan-2-yl)-8'-oxa-5',6'-d...)
Affinity DataIC50:  133nMAssay Description:Activity at 5HT2B receptor expressed in CHO cell assessed as inhibition of alpha-methyl-5HT-stimulated calcium releaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Hopital Saint-Louis

Curated by ChEMBL
LigandPNGBDBM50191211(12'-bromo-4'-[4-(difluoromethoxy)phenyl]-1-methyl-...)
Affinity DataIC50:  175nMAssay Description:Activity at 5HT2B receptor expressed in CHO cell assessed as inhibition of alpha-methyl-5HT-stimulated calcium releaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Hopital Saint-Louis

Curated by ChEMBL
LigandPNGBDBM50191172(12'-bromo-4'-(4-methoxyphenyl)-1-propyl-8'-oxa-5',...)
Affinity DataIC50:  179nMAssay Description:Activity at 5HT2B receptor expressed in CHO cell assessed as inhibition of alpha-methyl-5HT-stimulated calcium releaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Hopital Saint-Louis

Curated by ChEMBL
LigandPNGBDBM50191185(12'-bromo-4'-phenyl-1-(propan-2-yl)-8'-oxa-5',6'-d...)
Affinity DataIC50:  188nMAssay Description:Activity at 5HT2B receptor expressed in CHO cell assessed as inhibition of alpha-methyl-5HT-stimulated calcium releaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Hopital Saint-Louis

Curated by ChEMBL
LigandPNGBDBM50191204(4'-(4-chlorophenyl)-1-methyl-8'-oxa-5',6'-diazaspi...)
Affinity DataIC50:  280nMAssay Description:Activity at 5HT2B receptor expressed in CHO cell assessed as inhibition of alpha-methyl-5HT-stimulated calcium releaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Hopital Saint-Louis

Curated by ChEMBL
LigandPNGBDBM50191206(1-benzyl-4'-(4-chlorophenyl)-8'-oxa-5',6'-diazaspi...)
Affinity DataIC50:  350nMAssay Description:Activity at 5HT2B receptor expressed in CHO cell assessed as inhibition of alpha-methyl-5HT-stimulated calcium releaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Hopital Saint-Louis

Curated by ChEMBL
LigandPNGBDBM50191210(4'-(4-bromophenyl)-1-methyl-8'-oxa-5',6'-diazaspir...)
Affinity DataIC50:  426nMAssay Description:Activity at 5HT2B receptor expressed in CHO cell assessed as inhibition of alpha-methyl-5HT-stimulated calcium releaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Hopital Saint-Louis

Curated by ChEMBL
LigandPNGBDBM50191199(12'-bromo-4'-[2-(difluoromethoxy)phenyl]-1-methyl-...)
Affinity DataIC50:  427nMAssay Description:Activity at 5HT2B receptor expressed in CHO cell assessed as inhibition of alpha-methyl-5HT-stimulated calcium releaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Hopital Saint-Louis

Curated by ChEMBL
LigandPNGBDBM50191176(4'-(2-chlorophenyl)-1-propyl-8'-oxa-5',6'-diazaspi...)
Affinity DataIC50:  500nMAssay Description:Activity at 5HT2B receptor expressed in CHO cell assessed as inhibition of alpha-methyl-5HT-stimulated calcium releaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Hopital Saint-Louis

Curated by ChEMBL
LigandPNGBDBM50191192(12'-bromo-4'-(3,4-dichlorophenyl)-1-methyl-8'-oxa-...)
Affinity DataIC50:  542nMAssay Description:Activity at 5HT2B receptor expressed in CHO cell assessed as inhibition of alpha-methyl-5HT-stimulated calcium releaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Hopital Saint-Louis

Curated by ChEMBL
LigandPNGBDBM50191186(4'-(2-chlorophenyl)-1-methyl-8'-oxa-5',6'-diazaspi...)
Affinity DataIC50:  753nMAssay Description:Activity at 5HT2B receptor expressed in CHO cell assessed as inhibition of alpha-methyl-5HT-stimulated calcium releaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Hopital Saint-Louis

Curated by ChEMBL
LigandPNGBDBM50191195(12'-bromo-4'-(4-bromophenyl)-1-propyl-8'-oxa-5',6'...)
Affinity DataIC50:  791nMAssay Description:Activity at 5HT2B receptor expressed in CHO cell assessed as inhibition of alpha-methyl-5HT-stimulated calcium releaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Hopital Saint-Louis

Curated by ChEMBL
LigandPNGBDBM50191207(12'-bromo-4'-(2-chlorophenyl)-1-methyl-8'-oxa-5',6...)
Affinity DataIC50:  856nMAssay Description:Activity at 5HT2B receptor expressed in CHO cell assessed as inhibition of alpha-methyl-5HT-stimulated calcium releaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Hopital Saint-Louis

Curated by ChEMBL
LigandPNGBDBM50191203(4'-(4-bromophenyl)-10'-methoxy-1-methyl-8'-oxa-5',...)
Affinity DataIC50:  1.28E+3nMAssay Description:Activity at 5HT2B receptor expressed in CHO cell assessed as inhibition of alpha-methyl-5HT-stimulated calcium releaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Hopital Saint-Louis

Curated by ChEMBL
LigandPNGBDBM50191193(4'-(4-chlorophenyl)-10'-methoxy-1-methyl-8'-oxa-5'...)
Affinity DataIC50:  1.47E+3nMAssay Description:Activity at 5HT2B receptor expressed in CHO cell assessed as inhibition of alpha-methyl-5HT-stimulated calcium releaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Hopital Saint-Louis

Curated by ChEMBL
LigandPNGBDBM50191174(12'-bromo-4'-(4-methylphenyl)-1-propyl-8'-oxa-5',6...)
Affinity DataIC50:  5.00E+3nMAssay Description:Activity at 5HT2B receptor expressed in CHO cell assessed as inhibition of alpha-methyl-5HT-stimulated calcium releaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Hopital Saint-Louis

Curated by ChEMBL
LigandPNGBDBM50191205(12'-bromo-4'-(furan-2-yl)-1-methyl-8'-oxa-5',6'-di...)
Affinity DataIC50:  5.00E+3nMAssay Description:Activity at 5HT2B receptor expressed in CHO cell assessed as inhibition of alpha-methyl-5HT-stimulated calcium releaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Hopital Saint-Louis

Curated by ChEMBL
LigandPNGBDBM50191202(12'-bromo-4'-(3,4-dimethoxyphenyl)-1-methyl-8'-oxa...)
Affinity DataIC50:  5.00E+3nMAssay Description:Activity at 5HT2B receptor expressed in CHO cell assessed as inhibition of alpha-methyl-5HT-stimulated calcium releaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Hopital Saint-Louis

Curated by ChEMBL
LigandPNGBDBM50191177(12'-bromo-4'-(4-methoxyphenyl)-1-methyl-8'-oxa-5',...)
Affinity DataIC50:  5.00E+3nMAssay Description:Activity at 5HT2B receptor expressed in CHO cell assessed as inhibition of alpha-methyl-5HT-stimulated calcium releaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Hopital Saint-Louis

Curated by ChEMBL
LigandPNGBDBM50191198(12'-bromo-1-methyl-4'-(naphthalen-2-yl)-8'-oxa-5',...)
Affinity DataIC50:  5.00E+3nMAssay Description:Activity at 5HT2B receptor expressed in CHO cell assessed as inhibition of alpha-methyl-5HT-stimulated calcium releaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Hopital Saint-Louis

Curated by ChEMBL
LigandPNGBDBM50191183(12'-bromo-1-methyl-4'-(thiophen-2-yl)-8'-oxa-5',6'...)
Affinity DataIC50:  5.00E+3nMAssay Description:Activity at 5HT2B receptor expressed in CHO cell assessed as inhibition of alpha-methyl-5HT-stimulated calcium releaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Hopital Saint-Louis

Curated by ChEMBL
LigandPNGBDBM50191190(12'-bromo-4'-(2-methoxyphenyl)-1-methyl-8'-oxa-5',...)
Affinity DataIC50:  5.00E+3nMAssay Description:Activity at 5HT2B receptor expressed in CHO cell assessed as inhibition of alpha-methyl-5HT-stimulated calcium releaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Hopital Saint-Louis

Curated by ChEMBL
LigandPNGBDBM50191184(4,4-dimethyl-2-pyridin-4-yl-1,9b-dihydro-5-oxa-3,3...)
Affinity DataIC50:  5.00E+3nMAssay Description:Activity at 5HT2B receptor expressed in CHO cell assessed as inhibition of alpha-methyl-5HT-stimulated calcium releaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Hopital Saint-Louis

Curated by ChEMBL
LigandPNGBDBM50191189(4'-(4-bromophenyl)-1-(propan-2-yl)-8'-oxa-5',6'-di...)
Affinity DataIC50: >1.00E+4nMAssay Description:Activity at 5HT2B receptor expressed in CHO cell assessed as inhibition of alpha-methyl-5HT-stimulated calcium releaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Hopital Saint-Louis

Curated by ChEMBL
LigandPNGBDBM50191200(12'-bromo-1-methyl-4'-(naphthalen-1-yl)-8'-oxa-5',...)
Affinity DataIC50: >1.00E+4nMAssay Description:Activity at 5HT2B receptor expressed in CHO cell assessed as inhibition of alpha-methyl-5HT-stimulated calcium releaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed