Compile Data Set for Download or QSAR
maximum 50k data
Found 34 Enz. Inhib. hit(s) with all data for entry = 50020026
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50209674(CHEMBL391531 | N-(3-(5-fluoro-1H-indol-3-yl)propyl...)
Affinity DataKi:  1.20nMAssay Description:Displacement of [3H]paroxetine from 5HT reuptake site of rat cortical 5HTTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50209674(CHEMBL391531 | N-(3-(5-fluoro-1H-indol-3-yl)propyl...)
Affinity DataKi:  1.20nMAssay Description:Displacement of [3H]paroxetine from 5HT reuptake site of rat cortical 5HTTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50209679(CHEMBL234853 | N-(3-(5-fluoro-1H-indol-3-yl)propyl...)
Affinity DataKi:  1.30nMAssay Description:Displacement of [3H]paroxetine from 5HT reuptake site of rat cortical 5HTTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50209682(CHEMBL233624 | N-(4-(5-fluoro-1H-indol-3-yl)butyl)...)
Affinity DataKi:  1.5nMAssay Description:Displacement of [3H]paroxetine from 5HT reuptake site of rat cortical 5HTTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50209674(CHEMBL391531 | N-(3-(5-fluoro-1H-indol-3-yl)propyl...)
Affinity DataKi:  3nMAssay Description:Displacement of [3H]paroxetine from 5HT reuptake site of rat cortical 5HTTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50209679(CHEMBL234853 | N-(3-(5-fluoro-1H-indol-3-yl)propyl...)
Affinity DataKi:  5.10nMAssay Description:Displacement of [3H]paroxetine from 5HT reuptake site of rat cortical 5HTTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50209679(CHEMBL234853 | N-(3-(5-fluoro-1H-indol-3-yl)propyl...)
Affinity DataKi:  5.10nMAssay Description:Displacement of [3H]paroxetine from 5HT reuptake site of rat cortical 5HTTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50209677(CHEMBL233591 | N-(3-(5-fluoro-1H-indol-3-yl)propyl...)
Affinity DataKi:  8.80nMAssay Description:Displacement of [3H]paroxetine from 5HT reuptake site of rat cortical 5HTTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50191639(CHEMBL378073 | N-(3-(5-fluoro-1H-indol-3-yl)propyl...)
Affinity DataKi:  9nMAssay Description:Displacement of [3H]paroxetine from 5HT reuptake site of rat cortical 5HTTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50209681(CHEMBL395586 | N-(3-(5-fluoro-1H-indol-3-yl)propyl...)
Affinity DataKi:  9.20nMAssay Description:Displacement of [3H]paroxetine from 5HT reuptake site of rat cortical 5HTTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50209675(CHEMBL266908 | N-(4-(5-fluoro-1H-indol-3-yl)butyl)...)
Affinity DataKi:  12nMAssay Description:Displacement of [3H]paroxetine from 5HT reuptake site of rat cortical 5HTTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50209680(CHEMBL233622 | N-(3-(5-fluoro-1H-indol-3-yl)propyl...)
Affinity DataKi:  12.4nMAssay Description:Displacement of [3H]paroxetine from 5HT reuptake site of rat cortical 5HTTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50191639(CHEMBL378073 | N-(3-(5-fluoro-1H-indol-3-yl)propyl...)
Affinity DataKi:  15.8nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50209677(CHEMBL233591 | N-(3-(5-fluoro-1H-indol-3-yl)propyl...)
Affinity DataKi:  19.8nMAssay Description:Displacement of [3H]paroxetine from 5HT reuptake site of rat cortical 5HTTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50209677(CHEMBL233591 | N-(3-(5-fluoro-1H-indol-3-yl)propyl...)
Affinity DataKi:  19.8nMAssay Description:Displacement of [3H]paroxetine from 5HT reuptake site of rat cortical 5HTTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50209679(CHEMBL234853 | N-(3-(5-fluoro-1H-indol-3-yl)propyl...)
Affinity DataKi:  23.9nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50209678(CHEMBL401424 | N-(2-(5-fluoro-1H-indol-3-yl)ethyl)...)
Affinity DataKi:  30.5nMAssay Description:Displacement of [3H]paroxetine from 5HT reuptake site of rat cortical 5HTTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50209677(CHEMBL233591 | N-(3-(5-fluoro-1H-indol-3-yl)propyl...)
Affinity DataKi:  58nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50209677(CHEMBL233591 | N-(3-(5-fluoro-1H-indol-3-yl)propyl...)
Affinity DataKi:  58nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50209676(CHEMBL234875 | N-(2-(5-fluoro-1H-indol-3-yl)ethyl)...)
Affinity DataKi:  62.8nMAssay Description:Displacement of [3H]paroxetine from 5HT reuptake site of rat cortical 5HTTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50209677(CHEMBL233591 | N-(3-(5-fluoro-1H-indol-3-yl)propyl...)
Affinity DataKi:  63.5nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50209674(CHEMBL391531 | N-(3-(5-fluoro-1H-indol-3-yl)propyl...)
Affinity DataKi:  67.8nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50209674(CHEMBL391531 | N-(3-(5-fluoro-1H-indol-3-yl)propyl...)
Affinity DataKi:  67.8nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50209681(CHEMBL395586 | N-(3-(5-fluoro-1H-indol-3-yl)propyl...)
Affinity DataKi:  70.4nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50209679(CHEMBL234853 | N-(3-(5-fluoro-1H-indol-3-yl)propyl...)
Affinity DataKi:  313nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50209679(CHEMBL234853 | N-(3-(5-fluoro-1H-indol-3-yl)propyl...)
Affinity DataKi:  314nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50209674(CHEMBL391531 | N-(3-(5-fluoro-1H-indol-3-yl)propyl...)
Affinity DataKi:  392nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50209676(CHEMBL234875 | N-(2-(5-fluoro-1H-indol-3-yl)ethyl)...)
Affinity DataKi:  478nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50209679(CHEMBL234853 | N-(3-(5-fluoro-1H-indol-3-yl)propyl...)
Affinity DataEC50:  116nMAssay Description:Agonist activity at human 5HT1A receptor expressed in CHO membrane assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50209674(CHEMBL391531 | N-(3-(5-fluoro-1H-indol-3-yl)propyl...)
Affinity DataEC50:  332nMAssay Description:Agonist activity at human 5HT1A receptor expressed in CHO membrane assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50209674(CHEMBL391531 | N-(3-(5-fluoro-1H-indol-3-yl)propyl...)
Affinity DataEC50:  332nMAssay Description:Agonist activity at human 5HT1A receptor expressed in CHO membrane assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50209677(CHEMBL233591 | N-(3-(5-fluoro-1H-indol-3-yl)propyl...)
Affinity DataEC50:  301nMAssay Description:Agonist activity at human 5HT1A receptor expressed in CHO membrane assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50209677(CHEMBL233591 | N-(3-(5-fluoro-1H-indol-3-yl)propyl...)
Affinity DataEC50:  301nMAssay Description:Agonist activity at human 5HT1A receptor expressed in CHO membrane assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50209679(CHEMBL234853 | N-(3-(5-fluoro-1H-indol-3-yl)propyl...)
Affinity DataEC50:  116nMAssay Description:Agonist activity at human 5HT1A receptor expressed in CHO membrane assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed