Compile Data Set for Download or QSAR
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Found 7 Enz. Inhib. hit(s) with all data for entry = 50026616
TargetCalmodulin-sensitive adenylate cyclase(Bacillus anthracis)
University Of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50262712(3-[(9-oxo-9Hfluorene-1-carbonyl)-amino]-benzoic ac...)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of Bacillus anthracis edema factor-induced cytotoxicity in mouse RAW264.7 cells assessed as LDH release after 4 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalmodulin-sensitive adenylate cyclase(Bacillus anthracis)
University Of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50262713(4-(3-methoxy-phenyl)-3a,4,5,9b-tetrahydro-3H-cyclo...)
Affinity DataIC50:  1.73E+3nMAssay Description:Inhibition of Bacillus anthracis edema factor-induced cAMP secretion in mouse RAW264.7 cells after 4 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalmodulin-sensitive adenylate cyclase(Bacillus anthracis)
University Of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50262713(4-(3-methoxy-phenyl)-3a,4,5,9b-tetrahydro-3H-cyclo...)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of Bacillus anthracis edema factor-induced cytotoxicity in mouse RAW264.7 cells assessed as LDH release after 4 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalmodulin-sensitive adenylate cyclase(Bacillus anthracis)
University Of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50262712(3-[(9-oxo-9Hfluorene-1-carbonyl)-amino]-benzoic ac...)
Affinity DataIC50:  1.83E+3nMAssay Description:Inhibition of Bacillus anthracis edema factor-induced cAMP secretion in mouse RAW264.7 cells after 4 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalmodulin-sensitive adenylate cyclase(Bacillus anthracis)
University Of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50262711(4-[(anthracen-9-ylmethylene)-amino]-2-hydroxy-benz...)
Affinity DataIC50:  8.50E+3nMAssay Description:Inhibition of Bacillus anthracis edema factor-induced cAMP secretion in mouse RAW264.7 cells after 4 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalmodulin-sensitive adenylate cyclase(Bacillus anthracis)
University Of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50262711(4-[(anthracen-9-ylmethylene)-amino]-2-hydroxy-benz...)
Affinity DataIC50:  9.00E+3nMAssay Description:Inhibition of Bacillus anthracis edema factor-induced cytotoxicity in mouse RAW264.7 cells assessed as LDH release after 4 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalmodulin-sensitive adenylate cyclase(Bacillus anthracis)
University Of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50262663((3aS,4S,9bR)-4-(4-(methoxycarbonyl)phenyl)-3a,4,5,...)
Affinity DataIC50:  1.00E+5nMAssay Description:Inhibition of Bacillus anthracis edema factor-induced cytotoxicity in mouse RAW264.7 cells assessed as LDH release after 4 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed