Compile Data Set for Download or QSAR
maximum 50k data
Found 9 Enz. Inhib. hit(s) with all data for entry = 50047508
TargetTyrosinase(Homo sapiens (Human))
Peking University

Curated by ChEMBL
LigandPNGBDBM50172095(CHEBI:69084 | Glyasperin D)
Affinity DataIC50:  154nMAssay Description:Inhibition of tyrosinase (unknown origin) using L-tyrosine as substrate assessed as oxidation of L-tyrosine after 15 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosinase(Homo sapiens (Human))
Peking University

Curated by ChEMBL
LigandPNGBDBM50172096(CHEBI:69089 | Glyasperin C)
Affinity DataIC50:  177nMAssay Description:Inhibition of tyrosinase (unknown origin) using L-tyrosine as substrate assessed as oxidation of L-tyrosine after 15 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Peking University

Curated by ChEMBL
LigandPNGBDBM10404((1S,12S,14R)-9-methoxy-4-methyl-11-oxa-4-azatetrac...)
Affinity DataIC50:  300nMAssay Description:Inhibition AChE (unknown origin) using ATCI as substrate assessed as hydrolysis of ATCI after 10 mins measured every 1 min for 10 timesMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Peking University

Curated by ChEMBL
LigandPNGBDBM50172094(CHEMBL3808919)
Affinity DataIC50:  400nMAssay Description:Inhibition of recombinant human PTP1B assessed as hydrolysis of p-nitrophenyl phosphateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosinase(Homo sapiens (Human))
Peking University

Curated by ChEMBL
LigandPNGBDBM7462(3,5,7-trihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of tyrosinase (unknown origin) using L-tyrosine as substrate assessed as oxidation of L-tyrosine after 15 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Peking University

Curated by ChEMBL
LigandPNGBDBM50172093(CHEMBL3809403)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of recombinant human PTP1B assessed as hydrolysis of p-nitrophenyl phosphateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Peking University

Curated by ChEMBL
LigandPNGBDBM50148911((3beta)-3-hydroxyurs-12-en-28-oic acid | 3beta-hyd...)
Affinity DataIC50:  5.20E+3nMAssay Description:Inhibition of recombinant human PTP1B assessed as hydrolysis of p-nitrophenyl phosphateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Peking University

Curated by ChEMBL
LigandPNGBDBM50172097(CHEMBL3809337)
Affinity DataIC50:  9.90E+3nMAssay Description:Inhibition AChE (unknown origin) using ATCI as substrate assessed as hydrolysis of ATCI after 10 mins measured every 1 min for 10 timesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Peking University

Curated by ChEMBL
LigandPNGBDBM50172098(CHEBI:69082 | Licoricidin)
Affinity DataIC50:  1.55E+4nMAssay Description:Inhibition AChE (unknown origin) using ATCI as substrate assessed as hydrolysis of ATCI after 10 mins measured every 1 min for 10 timesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed