Compile Data Set for Download or QSAR
maximum 50k data
Found 46 Enz. Inhib. hit(s) with all data for entry = 50035376
TargetNociceptin receptor(Homo sapiens (Human))
Sri International

Curated by ChEMBL
LigandPNGBDBM21842((2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-6-amino-2-[(2...)
Affinity DataKi:  0.0600nMAssay Description:Binding affinity for human nociceptin (NOP) receptor using [3H]N/OFQ as radioligand transfected into CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Sri International

Curated by ChEMBL
LigandPNGBDBM50137564(1'-(4-isopropylcyclohexyl)-2-methyl-5-phenyl-(3aR,...)
Affinity DataKi:  0.490nMAssay Description:Binding affinity for human nociceptin (NOP) receptor using [3H]N/OFQ as radioligand transfected into CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Sri International

Curated by ChEMBL
LigandPNGBDBM50137565(1-((2R,6S,9aR)-6-Phenyl-octahydro-quinolizin-2-yl)...)
Affinity DataKi:  1.10nMAssay Description:Binding affinity for human opioid receptor kappa 1 using [3H]- U-69,593 as radioligand transfected into CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Sri International

Curated by ChEMBL
LigandPNGBDBM50137567(1-((2R,6S,9aR)-6-Cyclohexyl-octahydro-quinolizin-2...)
Affinity DataKi:  2.30nMAssay Description:Binding affinity for human opioid receptor kappa 1 using [3H]- U-69,593 as radioligand transfected into CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Sri International

Curated by ChEMBL
LigandPNGBDBM50137566(1-Ethyl-3-((2R,6S,9aR)-6-phenyl-octahydro-quinoliz...)
Affinity DataKi:  2.5nMAssay Description:Binding affinity for human opioid receptor mu 1 using [3H]- DAMGO as radioligand transfected into CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Sri International

Curated by ChEMBL
LigandPNGBDBM50137565(1-((2R,6S,9aR)-6-Phenyl-octahydro-quinolizin-2-yl)...)
Affinity DataKi:  5.20nMAssay Description:Binding affinity for human opioid receptor mu 1 using [3H]- DAMGO as radioligand transfected into CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Sri International

Curated by ChEMBL
LigandPNGBDBM50137565(1-((2R,6S,9aR)-6-Phenyl-octahydro-quinolizin-2-yl)...)
Affinity DataKi:  5.70nMAssay Description:Binding affinity for human nociceptin (NOP) receptor using [3H]N/OFQ as radioligand transfected into CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Sri International

Curated by ChEMBL
LigandPNGBDBM50137563(1-Ethyl-3-((2S,6S,9aR)-6-phenyl-octahydro-quinoliz...)
Affinity DataKi:  18nMAssay Description:Binding affinity for human opioid receptor mu 1 using [3H]- DAMGO as radioligand transfected into CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Sri International

Curated by ChEMBL
LigandPNGBDBM50137566(1-Ethyl-3-((2R,6S,9aR)-6-phenyl-octahydro-quinoliz...)
Affinity DataKi:  20nMAssay Description:Binding affinity for human nociceptin (NOP) receptor using [3H]N/OFQ as radioligand transfected into CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Sri International

Curated by ChEMBL
LigandPNGBDBM50137566(1-Ethyl-3-((2R,6S,9aR)-6-phenyl-octahydro-quinoliz...)
Affinity DataKi:  23nMAssay Description:Binding affinity for human opioid receptor kappa 1 using [3H]- U-69,593 as radioligand transfected into CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Sri International

Curated by ChEMBL
LigandPNGBDBM50137567(1-((2R,6S,9aR)-6-Cyclohexyl-octahydro-quinolizin-2...)
Affinity DataKi:  29nMAssay Description:Binding affinity for human nociceptin (NOP) receptor using [3H]N/OFQ as radioligand transfected into CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Sri International

Curated by ChEMBL
LigandPNGBDBM50137567(1-((2R,6S,9aR)-6-Cyclohexyl-octahydro-quinolizin-2...)
Affinity DataKi:  47nMAssay Description:Binding affinity for human opioid receptor mu 1 using [3H]- DAMGO as radioligand transfected into CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Sri International

Curated by ChEMBL
LigandPNGBDBM50137561(1-((2S,6S,9aR)-6-Phenyl-octahydro-quinolizin-2-yl)...)
Affinity DataKi:  48nMAssay Description:Binding affinity for human opioid receptor mu 1 using [3H]- DAMGO as radioligand transfected into CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Sri International

Curated by ChEMBL
LigandPNGBDBM50137568(1-((2S,6S,9aR)-6-Cyclohexyl-octahydro-quinolizin-2...)
Affinity DataKi:  119nMAssay Description:Binding affinity for human opioid receptor mu 1 using [3H]- DAMGO as radioligand transfected into CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Sri International

Curated by ChEMBL
LigandPNGBDBM50137568(1-((2S,6S,9aR)-6-Cyclohexyl-octahydro-quinolizin-2...)
Affinity DataKi:  189nMAssay Description:Binding affinity for human nociceptin (NOP) receptor using [3H]N/OFQ as radioligand transfected into CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Sri International

Curated by ChEMBL
LigandPNGBDBM50137568(1-((2S,6S,9aR)-6-Cyclohexyl-octahydro-quinolizin-2...)
Affinity DataKi:  227nMAssay Description:Binding affinity for human opioid receptor kappa 1 using [3H]- U-69,593 as radioligand transfected into CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Sri International

Curated by ChEMBL
LigandPNGBDBM50137561(1-((2S,6S,9aR)-6-Phenyl-octahydro-quinolizin-2-yl)...)
Affinity DataKi:  271nMAssay Description:Binding affinity for human opioid receptor kappa 1 using [3H]- U-69,593 as radioligand transfected into CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Sri International

Curated by ChEMBL
LigandPNGBDBM50137563(1-Ethyl-3-((2S,6S,9aR)-6-phenyl-octahydro-quinoliz...)
Affinity DataKi:  535nMAssay Description:Binding affinity for human nociceptin (NOP) receptor using [3H]N/OFQ as radioligand transfected into CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Sri International

Curated by ChEMBL
LigandPNGBDBM50137561(1-((2S,6S,9aR)-6-Phenyl-octahydro-quinolizin-2-yl)...)
Affinity DataKi:  786nMAssay Description:Binding affinity for human nociceptin (NOP) receptor using [3H]N/OFQ as radioligand transfected into CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Sri International

Curated by ChEMBL
LigandPNGBDBM50137563(1-Ethyl-3-((2S,6S,9aR)-6-phenyl-octahydro-quinoliz...)
Affinity DataKi:  987nMAssay Description:Binding affinity for human opioid receptor kappa 1 using [3H]- U-69,593 as radioligand transfected into CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Sri International

Curated by ChEMBL
LigandPNGBDBM50137566(1-Ethyl-3-((2R,6S,9aR)-6-phenyl-octahydro-quinoliz...)
Affinity DataKi:  1.49E+3nMAssay Description:Binding affinity for human opioid receptor delta 1 using [3H]- CL-DPDPE as radioligand transfected into CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Sri International

Curated by ChEMBL
LigandPNGBDBM50137565(1-((2R,6S,9aR)-6-Phenyl-octahydro-quinolizin-2-yl)...)
Affinity DataKi:  1.72E+3nMAssay Description:Binding affinity for human opioid receptor delta 1 using [3H]- CL-DPDPE as radioligand transfected into CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Sri International

Curated by ChEMBL
LigandPNGBDBM50137563(1-Ethyl-3-((2S,6S,9aR)-6-phenyl-octahydro-quinoliz...)
Affinity DataKi:  1.84E+3nMAssay Description:Binding affinity for human opioid receptor delta 1 using [3H]- CL-DPDPE as radioligand transfected into CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Sri International

Curated by ChEMBL
LigandPNGBDBM50137567(1-((2R,6S,9aR)-6-Cyclohexyl-octahydro-quinolizin-2...)
Affinity DataKi:  2.08E+3nMAssay Description:Binding affinity for human opioid receptor delta 1 using [3H]- CL-DPDPE as radioligand transfected into CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Sri International

Curated by ChEMBL
LigandPNGBDBM50137561(1-((2S,6S,9aR)-6-Phenyl-octahydro-quinolizin-2-yl)...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity for human opioid receptor delta 1 using [3H]- CL-DPDPE as radioligand transfected into CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Sri International

Curated by ChEMBL
LigandPNGBDBM50137568(1-((2S,6S,9aR)-6-Cyclohexyl-octahydro-quinolizin-2...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity for human opioid receptor delta 1 using [3H]- CL-DPDPE as radioligand transfected into CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Sri International

Curated by ChEMBL
LigandPNGBDBM50137562(1-(1-Benzyl-piperidin-4-yl)-1,3-dihydro-benzoimida...)
Affinity DataIC50:  200nMAssay Description:Ability to displace [125I]-Tyr14 at nociceptin (NOP) receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Sri International

Curated by ChEMBL
LigandPNGBDBM50137568(1-((2S,6S,9aR)-6-Cyclohexyl-octahydro-quinolizin-2...)
Affinity DataEC50: >1.00E+4nMAssay Description:Concentration required to stimulate [35S]GTP-gamma-S, binding to human opioid receptor kappa 1 in cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Sri International

Curated by ChEMBL
LigandPNGBDBM50137566(1-Ethyl-3-((2R,6S,9aR)-6-phenyl-octahydro-quinoliz...)
Affinity DataEC50:  210nMAssay Description:Concentration required to stimulate [35S]GTP-gamma-S, binding to human opioid receptor kappa 1 in cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Sri International

Curated by ChEMBL
LigandPNGBDBM50137565(1-((2R,6S,9aR)-6-Phenyl-octahydro-quinolizin-2-yl)...)
Affinity DataEC50:  4.70nMAssay Description:Concentration required to stimulate [35S]GTP-gamma-S, binding to human opioid receptor kappa 1 in cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Sri International

Curated by ChEMBL
LigandPNGBDBM50137567(1-((2R,6S,9aR)-6-Cyclohexyl-octahydro-quinolizin-2...)
Affinity DataEC50: >1.00E+4nMAssay Description:Concentration required to stimulate [35S]GTP-gamma-S, binding to human opioid receptor mu 1 in cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Sri International

Curated by ChEMBL
LigandPNGBDBM50137561(1-((2S,6S,9aR)-6-Phenyl-octahydro-quinolizin-2-yl)...)
Affinity DataEC50: >1.00E+4nMAssay Description:Concentration required to stimulate [35S]GTP-gamma-S, binding to human opioid receptor mu 1 in cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Sri International

Curated by ChEMBL
LigandPNGBDBM50137566(1-Ethyl-3-((2R,6S,9aR)-6-phenyl-octahydro-quinoliz...)
Affinity DataEC50:  165nMAssay Description:Concentration required to stimulate [35S]GTP-gamma-S, binding to human NOP receptor in cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Sri International

Curated by ChEMBL
LigandPNGBDBM50137565(1-((2R,6S,9aR)-6-Phenyl-octahydro-quinolizin-2-yl)...)
Affinity DataEC50:  65nMAssay Description:Concentration required to stimulate [35S]GTP-gamma-S, binding to human NOP receptor in cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Sri International

Curated by ChEMBL
LigandPNGBDBM50137565(1-((2R,6S,9aR)-6-Phenyl-octahydro-quinolizin-2-yl)...)
Affinity DataEC50:  198nMAssay Description:Concentration required to stimulate [35S]GTP-gamma-S, binding to human opioid receptor mu 1 in cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Sri International

Curated by ChEMBL
LigandPNGBDBM50137568(1-((2S,6S,9aR)-6-Cyclohexyl-octahydro-quinolizin-2...)
Affinity DataEC50: >1.00E+4nMAssay Description:Concentration required to stimulate [35S]GTP-gamma-S, binding to human NOP receptor in cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Sri International

Curated by ChEMBL
LigandPNGBDBM50137563(1-Ethyl-3-((2S,6S,9aR)-6-phenyl-octahydro-quinoliz...)
Affinity DataEC50: >1.00E+4nMAssay Description:Concentration required to stimulate [35S]GTP-gamma-S, binding to human NOP receptor in cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Sri International

Curated by ChEMBL
LigandPNGBDBM50137568(1-((2S,6S,9aR)-6-Cyclohexyl-octahydro-quinolizin-2...)
Affinity DataEC50: >1.00E+4nMAssay Description:Concentration required to stimulate [35S]GTP-gamma-S, binding to human opioid receptor mu 1 in cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Sri International

Curated by ChEMBL
LigandPNGBDBM50137563(1-Ethyl-3-((2S,6S,9aR)-6-phenyl-octahydro-quinoliz...)
Affinity DataEC50: >1.00E+4nMAssay Description:Concentration required to stimulate [35S]GTP-gamma-S, binding to human opioid receptor mu 1 in cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Sri International

Curated by ChEMBL
LigandPNGBDBM50137566(1-Ethyl-3-((2R,6S,9aR)-6-phenyl-octahydro-quinoliz...)
Affinity DataEC50:  105nMAssay Description:Concentration required to stimulate [35S]GTP-gamma-S, binding to human opioid receptor mu 1 in cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Sri International

Curated by ChEMBL
LigandPNGBDBM50137567(1-((2R,6S,9aR)-6-Cyclohexyl-octahydro-quinolizin-2...)
Affinity DataEC50:  678nMAssay Description:Concentration required to stimulate [35S]GTP-gamma-S, binding to human NOP receptor in cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Sri International

Curated by ChEMBL
LigandPNGBDBM50137561(1-((2S,6S,9aR)-6-Phenyl-octahydro-quinolizin-2-yl)...)
Affinity DataEC50: >1.00E+4nMAssay Description:Concentration required to stimulate [35S]GTP-gamma-S, binding to human NOP receptor in cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Sri International

Curated by ChEMBL
LigandPNGBDBM50137561(1-((2S,6S,9aR)-6-Phenyl-octahydro-quinolizin-2-yl)...)
Affinity DataEC50: >1.00E+4nMAssay Description:Concentration required to stimulate [35S]GTP-gamma-S, binding to human opioid receptor kappa 1 in cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Sri International

Curated by ChEMBL
LigandPNGBDBM21842((2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-6-amino-2-[(2...)
Affinity DataEC50:  4nMAssay Description:Concentration required to stimulate [35S]GTP-gamma-S, binding to human NOP receptor in cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Sri International

Curated by ChEMBL
LigandPNGBDBM50137567(1-((2R,6S,9aR)-6-Cyclohexyl-octahydro-quinolizin-2...)
Affinity DataEC50:  21nMAssay Description:Concentration required to stimulate [35S]GTP-gamma-S, binding to human opioid receptor kappa 1 in cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Sri International

Curated by ChEMBL
LigandPNGBDBM50137563(1-Ethyl-3-((2S,6S,9aR)-6-phenyl-octahydro-quinoliz...)
Affinity DataEC50: >1.00E+4nMAssay Description:Concentration required to stimulate [35S]GTP-gamma-S, binding to human opioid receptor kappa 1 in cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed