Compile Data Set for Download or QSAR
maximum 50k data
Found 51 Enz. Inhib. hit(s) with all data for entry = 50035686
TargetAromatase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50024479((4-Chloro-phenyl)-cyclopropyl-pyrimidin-5-yl-metha...)
Affinity DataEC50:  5.70E+3nMAssay Description:In vitro inhibition of cytochrome P450 19A1 by rat ovarian microsomes incubated with [3H]androstenedione and NADPH-generating system.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50024525((4-Chloro-phenyl)-(3-fluoro-phenyl)-pyrimidin-5-yl...)
Affinity DataEC50:  1.65E+3nMAssay Description:In vitro inhibition of cytochrome P450 19A1 by rat ovarian microsomes incubated with [3H]androstenedione and NADPH-generating system.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50024481((4-Chloro-phenyl)-pyrimidin-5-yl-(4-trifluoromethy...)
Affinity DataEC50:  66nMAssay Description:In vitro inhibition of cytochrome P450 19A1 by rat ovarian microsomes incubated with [3H]androstenedione and NADPH-generating system.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50024482(CHEMBL284636 | Phenyl-pyrimidin-5-yl-(4-trifluorom...)
Affinity DataEC50:  1.95E+3nMAssay Description:In vitro inhibition of cytochrome P450 19A1 by rat ovarian microsomes incubated with [3H]androstenedione and NADPH-generating system.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50024483((4-Nitro-phenyl)-phenyl-pyrimidin-5-yl-methanol | ...)
Affinity DataEC50:  270nMAssay Description:In vitro inhibition of cytochrome P450 19A1 by rat ovarian microsomes incubated with [3H]androstenedione and NADPH-generating system.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50024484(5-[1,1,2-Tris-(4-chloro-phenyl)-ethyl]-pyrimidine ...)
Affinity DataEC50: >2.00E+3nMAssay Description:In vitro inhibition of cytochrome P450 19A1 by rat ovarian microsomes incubated with [3H]androstenedione and NADPH-generating system.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50024485(5-[1,1-Bis-(4-chloro-phenyl)-2-phenyl-ethyl]-pyrim...)
Affinity DataEC50:  1.01E+3nMAssay Description:In vitro inhibition of cytochrome P450 19A1 by rat ovarian microsomes incubated with [3H]androstenedione and NADPH-generating system.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50024486(Bis-(4-chloro-phenyl)-(1-oxy-pyrimidin-5-yl)-metha...)
Affinity DataEC50: >2.00E+3nMAssay Description:In vitro inhibition of cytochrome P450 19A1 by rat ovarian microsomes incubated with [3H]androstenedione and NADPH-generating system.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50024487(1-(4-Chloro-phenyl)-2-methyl-1-pyrimidin-5-yl-prop...)
Affinity DataEC50: >2.00E+3nMAssay Description:In vitro inhibition of cytochrome P450 19A1 by rat ovarian microsomes incubated with [3H]androstenedione and NADPH-generating system.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50024489(5-[Bis-(4-chloro-phenyl)-methylene]-1,4,5,6-tetrah...)
Affinity DataEC50:  2.70E+3nMAssay Description:In vitro inhibition of cytochrome P450 19A1 by rat ovarian microsomes incubated with [3H]androstenedione and NADPH-generating system.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50024490(5-[Chloro-bis-(4-chloro-phenyl)-methyl]-pyrimidine...)
Affinity DataEC50:  275nMAssay Description:In vitro inhibition of cytochrome P450 19A1 by rat ovarian microsomes incubated with [3H]androstenedione and NADPH-generating system.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50024488(Bis-(4-fluoro-phenyl)-pyrimidin-5-yl-methanol | CH...)
Affinity DataEC50:  530nMAssay Description:In vitro inhibition of cytochrome P450 19A1 by rat ovarian microsomes incubated with [3H]androstenedione and NADPH-generating system.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM9460(3-(4-aminophenyl)-3-ethyl-piperidine-2,6-dione | 3...)
Affinity DataEC50:  260nMAssay Description:In vitro inhibition of cytochrome P450 19A1 by rat ovarian microsomes incubated with [3H]androstenedione and NADPH-generating system.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM31772(1-[2-(2,4-dichlorobenzyl)oxy-2-(2,4-dichlorophenyl...)
Affinity DataEC50:  400nMAssay Description:In vitro inhibition of cytochrome P450 19A1 by rat ovarian microsomes incubated with [3H]androstenedione and NADPH-generating system.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50024491(5-[(2-Chloro-phenyl)-fluoro-(4-fluoro-phenyl)-meth...)
Affinity DataEC50:  1.20E+3nMAssay Description:In vitro inhibition of cytochrome P450 19A1 by rat ovarian microsomes incubated with [3H]androstenedione and NADPH-generating system.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50024492(CHEMBL29670 | Diphenyl-pyrimidin-5-yl-methanol)
Affinity DataEC50: >2.00E+3nMAssay Description:In vitro inhibition of cytochrome P450 19A1 by rat ovarian microsomes incubated with [3H]androstenedione and NADPH-generating system.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50014324(5-[Bis-(4-chloro-phenyl)-methyl]-pyrimidine | 5-[B...)
Affinity DataEC50:  55nMAssay Description:In vitro inhibition of cytochrome P450 19A1 by rat ovarian microsomes incubated with [3H]androstenedione and NADPH-generating system.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50024494((4-Fluoro-phenyl)-phenyl-pyrimidin-5-yl-methanol |...)
Affinity DataEC50: >2.20E+3nMAssay Description:In vitro inhibition of cytochrome P450 19A1 by rat ovarian microsomes incubated with [3H]androstenedione and NADPH-generating system.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50024493(CHEMBL30081 | Cyclopropyl-(4-fluoro-phenyl)-pyrimi...)
Affinity DataEC50:  4.20E+3nMAssay Description:In vitro inhibition of cytochrome P450 19A1 by rat ovarian microsomes incubated with [3H]androstenedione and NADPH-generating system.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50024495(CHEMBL283085 | Pyrimidin-5-yl-di-p-tolyl-methanol)
Affinity DataEC50:  410nMAssay Description:In vitro inhibition of cytochrome P450 19A1 by rat ovarian microsomes incubated with [3H]androstenedione and NADPH-generating system.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50024497(2-Methyl-1-(5-methyl-thiophen-2-yl)-1-pyrimidin-5-...)
Affinity DataEC50: >2.00E+3nMAssay Description:In vitro inhibition of cytochrome P450 19A1 by rat ovarian microsomes incubated with [3H]androstenedione and NADPH-generating system.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50024496(CHEMBL29412 | Pyrimidin-5-yl-di-thiophen-2-yl-meth...)
Affinity DataEC50: >2.00E+3nMAssay Description:In vitro inhibition of cytochrome P450 19A1 by rat ovarian microsomes incubated with [3H]androstenedione and NADPH-generating system.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50024498(5-[1,1-Bis-(4-chloro-phenyl)-propyl]-pyrimidine | ...)
Affinity DataEC50:  2.95E+3nMAssay Description:In vitro inhibition of cytochrome P450 19A1 by rat ovarian microsomes incubated with [3H]androstenedione and NADPH-generating system.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50024499(1-(4-Methoxy-phenyl)-2-methyl-1-pyrimidin-5-yl-but...)
Affinity DataEC50: >2.00E+3nMAssay Description:In vitro inhibition of cytochrome P450 19A1 by rat ovarian microsomes incubated with [3H]androstenedione and NADPH-generating system.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50024500(CHEMBL29140 | Phenyl-pyrimidin-5-yl-thiophen-2-yl-...)
Affinity DataEC50: >2.00E+3nMAssay Description:In vitro inhibition of cytochrome P450 19A1 by rat ovarian microsomes incubated with [3H]androstenedione and NADPH-generating system.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50024501((4-Bromo-phenyl)-cyclopropyl-pyrimidin-5-yl-methan...)
Affinity DataEC50:  5.40E+3nMAssay Description:In vitro inhibition of cytochrome P450 19A1 by rat ovarian microsomes incubated with [3H]androstenedione and NADPH-generating system.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50024502(1-(4-Methoxy-phenyl)-2,2-dimethyl-1-pyrimidin-5-yl...)
Affinity DataEC50: >2.00E+3nMAssay Description:In vitro inhibition of cytochrome P450 19A1 by rat ovarian microsomes incubated with [3H]androstenedione and NADPH-generating system.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50024503(CHEMBL28860 | Cyclopropyl-pyrimidin-5-yl-thiophen-...)
Affinity DataEC50: >2.00E+3nMAssay Description:In vitro inhibition of cytochrome P450 19A1 by rat ovarian microsomes incubated with [3H]androstenedione and NADPH-generating system.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50024504((2-Chloro-4-methoxy-phenyl)-(4-chloro-phenyl)-pyri...)
Affinity DataEC50:  4.30E+3nMAssay Description:In vitro inhibition of cytochrome P450 19A1 by rat ovarian microsomes incubated with [3H]androstenedione and NADPH-generating system.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50024506((4-Chloro-phenyl)-phenyl-pyrimidin-5-yl-methanol |...)
Affinity DataEC50: >2.00E+3nMAssay Description:In vitro inhibition of cytochrome P450 19A1 by rat ovarian microsomes incubated with [3H]androstenedione and NADPH-generating system.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50024505((3,4-Dimethyl-phenyl)-(4-methoxy-3-methyl-phenyl)-...)
Affinity DataEC50:  1.40E+3nMAssay Description:In vitro inhibition of cytochrome P450 19A1 by rat ovarian microsomes incubated with [3H]androstenedione and NADPH-generating system.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50024507((3,4-Dimethyl-phenyl)-phenyl-pyrimidin-5-yl-methan...)
Affinity DataEC50:  3.20E+3nMAssay Description:In vitro inhibition of cytochrome P450 19A1 by rat ovarian microsomes incubated with [3H]androstenedione and NADPH-generating system.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50024512(CHEMBL280781 | Cyclohexyl-pyrimidin-5-yl-p-tolyl-m...)
Affinity DataEC50: >2.00E+3nMAssay Description:In vitro inhibition of cytochrome P450 19A1 by rat ovarian microsomes incubated with [3H]androstenedione and NADPH-generating system.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50024511((4-Chloro-phenyl)-(2-chloro-phenyl)-pyrimidin-5-yl...)
Affinity DataEC50:  4.10E+3nMAssay Description:In vitro inhibition of cytochrome P450 19A1 by rat ovarian microsomes incubated with [3H]androstenedione and NADPH-generating system.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50024508(5-[(4-Chloro-phenyl)-fluoro-(4-fluoro-phenyl)-meth...)
Affinity DataEC50:  195nMAssay Description:In vitro inhibition of cytochrome P450 19A1 by rat ovarian microsomes incubated with [3H]androstenedione and NADPH-generating system.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50024510(CHEMBL417120 | Cyclopentyl-cyclopropyl-pyrimidin-5...)
Affinity DataEC50: >2.00E+3nMAssay Description:In vitro inhibition of cytochrome P450 19A1 by rat ovarian microsomes incubated with [3H]androstenedione and NADPH-generating system.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50024509(CHEMBL285844 | Cyclobutyl-(4-methoxy-phenyl)-pyrim...)
Affinity DataEC50: >2.00E+3nMAssay Description:In vitro inhibition of cytochrome P450 19A1 by rat ovarian microsomes incubated with [3H]androstenedione and NADPH-generating system.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50024513(6-Acetylsulfanyl-8-[2-[(4-amino-2-methyl-pyrimidin...)
Affinity DataEC50:  140nMAssay Description:In vitro inhibition of cytochrome P450 19A1 by rat ovarian microsomes incubated with [3H]androstenedione and NADPH-generating system.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50014815(Bis-(4-chloro-phenyl)-pyrimidin-5-yl-methanol | CH...)
Affinity DataEC50:  71nMAssay Description:In vitro inhibition of cytochrome P450 19A1 by rat ovarian microsomes incubated with [3H]androstenedione and NADPH-generating system.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50024515(Bicyclo[2.2.1]hept-2-yl-(4-chloro-phenyl)-pyrimidi...)
Affinity DataEC50:  7.80E+3nMAssay Description:In vitro inhibition of cytochrome P450 19A1 by rat ovarian microsomes incubated with [3H]androstenedione and NADPH-generating system.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50024514(CHEMBL280558 | Cyclopropyl-(4-methoxy-phenyl)-pyri...)
Affinity DataEC50: >2.00E+3nMAssay Description:In vitro inhibition of cytochrome P450 19A1 by rat ovarian microsomes incubated with [3H]androstenedione and NADPH-generating system.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50024517(CHEMBL27797 | Cyclooctyl-(4-methoxy-phenyl)-pyrimi...)
Affinity DataEC50:  6.20E+3nMAssay Description:In vitro inhibition of cytochrome P450 19A1 by rat ovarian microsomes incubated with [3H]androstenedione and NADPH-generating system.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50024519((4-Chloro-phenyl)-(3-chloro-phenyl)-pyrimidin-5-yl...)
Affinity DataEC50:  350nMAssay Description:In vitro inhibition of cytochrome P450 19A1 by rat ovarian microsomes incubated with [3H]androstenedione and NADPH-generating system.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50024518((4-Chloro-phenyl)-cyclohexyl-pyrimidin-5-yl-methan...)
Affinity DataEC50:  4.00E+3nMAssay Description:In vitro inhibition of cytochrome P450 19A1 by rat ovarian microsomes incubated with [3H]androstenedione and NADPH-generating system.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50024516(5-[Bis-(4-chloro-phenyl)-fluoro-methyl]-pyrimidine...)
Affinity DataEC50:  78nMAssay Description:In vitro inhibition of cytochrome P450 19A1 by rat ovarian microsomes incubated with [3H]androstenedione and NADPH-generating system.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50024521((4-Fluoro-phenyl)-(3-fluoro-phenyl)-pyrimidin-5-yl...)
Affinity DataEC50:  1.15E+3nMAssay Description:In vitro inhibition of cytochrome P450 19A1 by rat ovarian microsomes incubated with [3H]androstenedione and NADPH-generating system.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50367548(CHEMBL1794921)
Affinity DataEC50:  50nMAssay Description:In vitro inhibition of cytochrome P450 19A1 by rat ovarian microsomes incubated with [3H]androstenedione and NADPH-generating system.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50024523((4-Methoxy-phenyl)-phenyl-pyrimidin-5-yl-methanol ...)
Affinity DataEC50: >2.00E+3nMAssay Description:In vitro inhibition of cytochrome P450 19A1 by rat ovarian microsomes incubated with [3H]androstenedione and NADPH-generating system.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50024522((4-Chloro-phenyl)-(4-fluoro-phenyl)-pyrimidin-5-yl...)
Affinity DataEC50:  180nMAssay Description:In vitro inhibition of cytochrome P450 19A1 by rat ovarian microsomes incubated with [3H]androstenedione and NADPH-generating system.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50024524(5-[1,1-Bis-(4-chloro-phenyl)-ethyl]-pyrimidine | C...)
Affinity DataEC50:  82nMAssay Description:In vitro inhibition of cytochrome P450 19A1 by rat ovarian microsomes incubated with [3H]androstenedione and NADPH-generating system.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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