Compile Data Set for Download or QSAR
maximum 50k data
Found 37 Enz. Inhib. hit(s) with all data for entry = 50035955
TargetThymidylate synthase(Mus musculus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50006687((S)-2-(4-(((2-methyl-4-oxo-3,4-dihydroquinazolin-6...)
Affinity DataIC50:  40nMAssay Description:In vitro inhibition of partially purified L1210 thymidylate synthase (TS).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50012036((S)-2-(5-(((2-methyl-4-oxo-3,4-dihydroquinazolin-6...)
Affinity DataIC50:  40nMAssay Description:In vitro inhibition of partially purified L1210 thymidylate synthase (TS).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50012044((S)-2-(5-(ethyl((2-methyl-4-oxo-3,4-dihydroquinazo...)
Affinity DataIC50:  150nMAssay Description:In vitro inhibition of partially purified L1210 thymidylate synthase (TS).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50012038((S)-2-(5-((2-fluoroethyl)((2-methyl-4-oxo-3,4-dihy...)
Affinity DataIC50:  160nMAssay Description:In vitro inhibition of partially purified L1210 thymidylate synthase (TS).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50012022(2-({5-[(2-Fluoro-ethyl)-(2-methyl-4-oxo-3,4-dihydr...)
Affinity DataIC50:  190nMAssay Description:In vitro inhibition of partially purified L1210 thymidylate synthase (TS).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50012051(2-({5-[Ethyl-(2-fluoromethyl-4-oxo-3,4-dihydro-qui...)
Affinity DataIC50:  220nMAssay Description:In vitro inhibition of partially purified L1210 thymidylate synthase (TS).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50012048(2-({5-[Ethyl-(2-methyl-4-oxo-3,4-dihydro-quinazoli...)
Affinity DataIC50:  230nMAssay Description:In vitro inhibition of partially purified L1210 thymidylate synthase (TS).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50012043(2-({5-[(2-Methyl-4-oxo-3,4-dihydro-quinazolin-6-yl...)
Affinity DataIC50:  230nMAssay Description:In vitro inhibition of partially purified L1210 thymidylate synthase (TS).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50006691((S)-2-(4-(methyl((2-methyl-4-oxo-3,4-dihydroquinaz...)
Affinity DataIC50:  250nMAssay Description:In vitro inhibition of partially purified L1210 thymidylate synthase (TS).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50012045((S)-2-(4-(ethyl((2-methyl-4-oxo-3,4-dihydroquinazo...)
Affinity DataIC50:  260nMAssay Description:In vitro inhibition of partially purified L1210 thymidylate synthase (TS).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50012019((S)-2-(5-(methyl((2-methyl-4-oxo-3,4-dihydroquinaz...)
Affinity DataIC50:  350nMAssay Description:In vitro inhibition of partially purified L1210 thymidylate synthase (TS).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50012026(2-({5-[(2-Hydroxy-ethyl)-(2-methyl-4-oxo-3,4-dihyd...)
Affinity DataIC50:  420nMAssay Description:In vitro inhibition of partially purified L1210 thymidylate synthase (TS).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50012029(2-({5-[Methyl-(2-methyl-4-oxo-3,4-dihydro-quinazol...)
Affinity DataIC50:  420nMAssay Description:In vitro inhibition of partially purified L1210 thymidylate synthase (TS).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50012031(2-({5-[(2-Methyl-4-oxo-3,4-dihydro-quinazolin-6-yl...)
Affinity DataIC50:  440nMAssay Description:In vitro inhibition of partially purified L1210 thymidylate synthase (TS).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50012052(2-({5-[(2-Hydroxymethyl-4-oxo-3,4-dihydro-quinazol...)
Affinity DataIC50:  490nMAssay Description:In vitro inhibition of partially purified L1210 thymidylate synthase (TS).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50012041(2-({5-[(2-Fluoro-ethyl)-(2-methyl-4-oxo-3,4-dihydr...)
Affinity DataIC50:  550nMAssay Description:In vitro inhibition of partially purified L1210 thymidylate synthase (TS).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50012025(2-({5-[Ethyl-(2-methyl-4-oxo-3,4-dihydro-quinazoli...)
Affinity DataIC50:  580nMAssay Description:In vitro inhibition of partially purified L1210 thymidylate synthase (TS).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50012040(2-({5-[Methyl-(2-methyl-4-oxo-3,4-dihydro-quinazol...)
Affinity DataIC50:  670nMAssay Description:In vitro inhibition of partially purified L1210 thymidylate synthase (TS).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50012027(2-({2-[Ethyl-(2-methyl-4-oxo-3,4-dihydro-quinazoli...)
Affinity DataIC50:  760nMAssay Description:In vitro inhibition of partially purified L1210 thymidylate synthase (TS).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50012037((S)-2-(5-(allyl((2-methyl-4-oxo-3,4-dihydroquinazo...)
Affinity DataIC50:  760nMAssay Description:In vitro inhibition of partially purified L1210 thymidylate synthase (TS).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50012049(2-({5-[Ethyl-(2-fluoromethyl-4-oxo-3,4-dihydro-qui...)
Affinity DataIC50:  930nMAssay Description:In vitro inhibition of partially purified L1210 thymidylate synthase (TS).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50012028(2-({5-[Ethyl-(2-methyl-4-oxo-3,4-dihydro-quinazoli...)
Affinity DataIC50:  940nMAssay Description:In vitro inhibition of partially purified L1210 thymidylate synthase (TS).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50012039(2-({5-[Ethyl-(2-hydroxymethyl-4-oxo-3,4-dihydro-qu...)
Affinity DataIC50:  1.03E+3nMAssay Description:In vitro inhibition of partially purified L1210 thymidylate synthase (TS).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50012050(2-({5-[(2-Fluoro-ethyl)-(2-fluoromethyl-4-oxo-3,4-...)
Affinity DataIC50:  1.07E+3nMAssay Description:In vitro inhibition of partially purified L1210 thymidylate synthase (TS).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50012042(2-({5-[Allyl-(2-methyl-4-oxo-3,4-dihydro-quinazoli...)
Affinity DataIC50:  1.07E+3nMAssay Description:In vitro inhibition of partially purified L1210 thymidylate synthase (TS).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50012032(2-({5-[(2-Hydroxy-ethyl)-(2-methyl-4-oxo-3,4-dihyd...)
Affinity DataIC50:  1.20E+3nMAssay Description:In vitro inhibition of partially purified L1210 thymidylate synthase (TS).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50012034(2-({5-[(2-Fluoromethyl-4-oxo-3,4-dihydro-quinazoli...)
Affinity DataIC50:  1.36E+3nMAssay Description:In vitro inhibition of partially purified L1210 thymidylate synthase (TS).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50012053(2-({5-[(2-Hydroxymethyl-4-oxo-3,4-dihydro-quinazol...)
Affinity DataIC50:  1.36E+3nMAssay Description:In vitro inhibition of partially purified L1210 thymidylate synthase (TS).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50012030(2-({5-[Allyl-(2-methyl-4-oxo-3,4-dihydro-quinazoli...)
Affinity DataIC50:  1.68E+3nMAssay Description:In vitro inhibition of partially purified L1210 thymidylate synthase (TS).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50012035(2-({5-[(3-Hydroxy-propyl)-(2-methyl-4-oxo-3,4-dihy...)
Affinity DataIC50:  1.74E+3nMAssay Description:In vitro inhibition of partially purified L1210 thymidylate synthase (TS).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50012047(2-({5-[(2-Methyl-4-oxo-3,4-dihydro-quinazolin-6-yl...)
Affinity DataIC50:  1.85E+3nMAssay Description:In vitro inhibition of partially purified L1210 thymidylate synthase (TS).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50012024((S)-2-(5-(methyl((2-methyl-4-oxo-3,4-dihydroquinaz...)
Affinity DataIC50:  2.34E+3nMAssay Description:In vitro inhibition of partially purified L1210 thymidylate synthase (TS).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50012020(2-({5-[Cyanomethyl-(2-methyl-4-oxo-3,4-dihydro-qui...)
Affinity DataIC50:  3.08E+3nMAssay Description:In vitro inhibition of partially purified L1210 thymidylate synthase (TS).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50012033(2-({5-[(3-Hydroxy-propyl)-(2-methyl-4-oxo-3,4-dihy...)
Affinity DataIC50:  3.36E+3nMAssay Description:In vitro inhibition of partially purified L1210 thymidylate synthase (TS).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50368273(CHEMBL1788164)
Affinity DataIC50:  4.25E+3nMAssay Description:In vitro inhibition of partially purified L1210 thymidylate synthase (TS).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50012046(2-({5-[(2-Methyl-4-oxo-3,4-dihydro-quinazolin-6-yl...)
Affinity DataIC50:  7.12E+3nMAssay Description:In vitro inhibition of partially purified L1210 thymidylate synthase (TS).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50012023(2-({5-[(2-Methyl-4-oxo-3,4-dihydro-quinazolin-6-yl...)
Affinity DataIC50:  2.48E+4nMAssay Description:In vitro inhibition of partially purified L1210 thymidylate synthase (TS).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed