Compile Data Set for Download or QSAR
maximum 50k data
Found 60 Enz. Inhib. hit(s) with all data for entry = 50037274
TargetD(4) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150141(2-[4-(3,4-Dimethyl-phenyl)-piperazin-1-ylmethyl]-1...)
Affinity DataKi:  1.5nMAssay Description:In vitro binding affinity tested on HEK293 cells co-transfected with human D4.4 receptor using [3H]spiperone as a radioligand in FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50145073(5-Fluoro-2-(4-pyridin-2-yl-piperazin-1-ylmethyl)-1...)
Affinity DataKi:  3.60nMAssay Description:Binding affinity towards human D4.4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150143(2-[4-(2,5-Dimethyl-phenyl)-piperazin-1-ylmethyl]-1...)
Affinity DataKi:  3.80nMAssay Description:In vitro binding affinity tested on HEK293 cells co-transfected with human D4.4 receptor using [3H]spiperone as a radioligand in FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50145079(2-(4-Phenyl-piperazin-1-ylmethyl)-1H-benzoimidazol...)
Affinity DataKi:  33nMAssay Description:Binding affinity tested against D4.2 receptor in Chinese hamster ovary cell line (CHO cells) using [3H]spiperone as a radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50145073(5-Fluoro-2-(4-pyridin-2-yl-piperazin-1-ylmethyl)-1...)
Affinity DataKi:  120nMAssay Description:Binding affinity towards human Dopamine receptor D2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50145075(2-((4-(pyridin-2-yl)piperazin-1-yl)methyl)-1H-benz...)
Affinity DataKi:  160nMAssay Description:In vitro binding affinity tested on human Dopamine receptor D2 using [3H]spiperon as a radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50145073(5-Fluoro-2-(4-pyridin-2-yl-piperazin-1-ylmethyl)-1...)
Affinity DataKi:  200nMAssay Description:Binding affinity towards human 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50145073(5-Fluoro-2-(4-pyridin-2-yl-piperazin-1-ylmethyl)-1...)
Affinity DataKi:  300nMAssay Description:Binding affinity towards human Opioid receptor kappa 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50145073(5-Fluoro-2-(4-pyridin-2-yl-piperazin-1-ylmethyl)-1...)
Affinity DataKi:  560nMAssay Description:Binding affinity towards human Dopamine receptor D3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50145075(2-((4-(pyridin-2-yl)piperazin-1-yl)methyl)-1H-benz...)
Affinity DataKi: >1.00E+4nMAssay Description:In vitro binding affinity tested on human 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50145075(2-((4-(pyridin-2-yl)piperazin-1-yl)methyl)-1H-benz...)
Affinity DataKi:  1.50E+4nMAssay Description:In vitro binding affinity tested on human Dopamine receptor D2 (long) using [3H]spiperon as a radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50145075(2-((4-(pyridin-2-yl)piperazin-1-yl)methyl)-1H-benz...)
Affinity DataKi:  5.10E+4nMAssay Description:In vitro binding affinity tested on human Dopamine receptor D2 (short) using [3H]spiperone as a radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50145075(2-((4-(pyridin-2-yl)piperazin-1-yl)methyl)-1H-benz...)
Affinity DataKi:  2.78E+6nMAssay Description:In vitro binding affinity tested on human 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150143(2-[4-(2,5-Dimethyl-phenyl)-piperazin-1-ylmethyl]-1...)
Affinity DataIC50:  1nMAssay Description:In vitro inhibitory concentration tested on human D4.4 receptor in HEK293 cells using FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150141(2-[4-(3,4-Dimethyl-phenyl)-piperazin-1-ylmethyl]-1...)
Affinity DataIC50:  5nMAssay Description:In vitro inhibitory concentration tested on human D4.4 receptor in HEK293 cells using FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150138(2-((S)-2-Methyl-4-pyridin-2-yl-piperazin-1-ylmethy...)
Affinity DataEC50:  52nMAssay Description:In vitro EC50 tested on HEK293 cells co-transfected with human Dopamine receptor D4.4 using FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150137(1'-(1H-Benzoimidazol-2-ylmethyl)-1',2',3',6'-tetra...)
Affinity DataEC50:  11nMAssay Description:In vitro effective concentration tested on HEK293 cells co-transfected with human D4.4 receptor using FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(RAT)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50001955((-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]qu...)
Affinity DataEC50:  5.5nMAssay Description:In vitro effective concentration tested on HEK293 cells co-transfected with rat Dopamine receptor D4 using FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50145078(2-[4-(2-Methoxy-phenyl)-piperazin-1-ylmethyl]-1H-b...)
Affinity DataEC50:  12.4nMAssay Description:In vitro EC50 tested on HEK293 cells co-transfected with human Dopamine receptor D4.4 using FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50056443((R)-5-Methylamino-5,6-dihydro-1H,4H-imidazo[4,5,1-...)
Affinity DataEC50:  165nMAssay Description:In vitro effective concentration tested on HEK293 cells co-transfected with human Dopamine receptor D2 using FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(RAT)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50145075(2-((4-(pyridin-2-yl)piperazin-1-yl)methyl)-1H-benz...)
Affinity DataEC50:  23.2nMAssay Description:In vitro effective concentration tested on HEK293 cells co-transfected with ferret Dopamine receptor D4 using FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50056443((R)-5-Methylamino-5,6-dihydro-1H,4H-imidazo[4,5,1-...)
Affinity DataEC50:  35nMAssay Description:In vitro effective concentration tested on HEK293 cells co-transfected with ferret Dopamine receptor D2 using FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150139(2-[4-(2-Methylsulfanyl-phenyl)-piperazin-1-ylmethy...)
Affinity DataEC50:  86nMAssay Description:In vitro EC50 tested on HEK293 cells co-transfected with human Dopamine receptor D4.4 using FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50145073(5-Fluoro-2-(4-pyridin-2-yl-piperazin-1-ylmethyl)-1...)
Affinity DataEC50:  527nMAssay Description:In vitro effective concentration tested on HEK293 cells co-transfected with ferret Dopamine receptor D2 using FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(RAT)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM55121(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Affinity DataEC50:  2.70nMAssay Description:In vitro effective concentration tested on HEK293 cells co-transfected with ferret Dopamine receptor D4 using FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150140(2-[4-(3-Fluoro-pyridin-2-yl)-piperazin-1-ylmethyl]...)
Affinity DataEC50:  24nMAssay Description:In vitro EC50 tested on HEK293 cells co-transfected with human Dopamine receptor D4.4 using FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50145075(2-((4-(pyridin-2-yl)piperazin-1-yl)methyl)-1H-benz...)
Affinity DataEC50:  12.4nMAssay Description:In vitro EC50 tested on HEK293 cells co-transfected with human Dopamine receptor D4.4 using FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM55121(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Affinity DataEC50:  1.10nMAssay Description:In vitro effective concentration tested on HEK293 cells co-transfected with rat Dopamine receptor D2 using FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50145081(2-[4-(2-Chloro-phenyl)-piperazin-1-ylmethyl]-1H-be...)
Affinity DataEC50:  7.20nMAssay Description:In vitro EC50 tested on HEK293 cells co-transfected with human Dopamine receptor D4.4 using FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150142(2-[4-(1H-Benzoimidazol-2-ylmethyl)-piperazin-1-yl]...)
Affinity DataEC50:  14.6nMAssay Description:In vitro EC50 tested on HEK293 cells co-transfected with human Dopamine receptor D4.4 using FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50001955((-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]qu...)
Affinity DataEC50:  1.80nMAssay Description:In vitro effective concentration tested on HEK293 cells co-transfected with ferret Dopamine receptor D2 using FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150145(2-[4-(1H-Benzoimidazol-2-ylmethyl)-piperazin-1-yl]...)
Affinity DataEC50:  13.9nMAssay Description:In vitro EC50 tested on HEK293 cells co-transfected with human Dopamine receptor D4.4 using FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50001955((-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]qu...)
Affinity DataEC50:  5.80nMAssay Description:In vitro effective concentration tested on HEK293 cells co-transfected with human Dopamine receptor D2 using FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50001955((-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]qu...)
Affinity DataEC50:  0.400nMAssay Description:In vitro effective concentration tested on HEK293 cells co-transfected with rat Dopamine receptor D2 using FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150144(2-((R)-2-Methyl-4-pyridin-2-yl-piperazin-1-ylmethy...)
Affinity DataEC50:  64nMAssay Description:In vitro EC50 tested on HEK293 cells co-transfected with human Dopamine receptor D4.4 using FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50145073(5-Fluoro-2-(4-pyridin-2-yl-piperazin-1-ylmethyl)-1...)
Affinity DataEC50:  32nMAssay Description:In vitro effective concentration tested on HEK293 cells co-transfected with human Dopamine receptor D4 using FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150147(6-Fluoro-2-(4-pyridin-2-yl-piperazin-1-ylmethyl)-1...)
Affinity DataEC50:  8nMAssay Description:In vitro EC50 tested on HEK293 cells co-transfected with human Dopamine receptor D4.4 using FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM55121(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Affinity DataEC50:  8nMAssay Description:In vitro effective concentration tested on HEK293 cells co-transfected with ferret Dopamine receptor D2 using FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(RAT)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50145075(2-((4-(pyridin-2-yl)piperazin-1-yl)methyl)-1H-benz...)
Affinity DataEC50:  14.3nMAssay Description:In vitro effective concentration tested on HEK293 cells co-transfected with rat Dopamine receptor D4 using FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150146(2-[2-(4-Pyridin-2-yl-piperazin-1-yl)-ethyl]-1H-ben...)
Affinity DataEC50:  23nMAssay Description:In vitro EC50 tested on HEK293 cells co-transfected with human Dopamine receptor D4.4 using FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(RAT)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50145073(5-Fluoro-2-(4-pyridin-2-yl-piperazin-1-ylmethyl)-1...)
Affinity DataEC50:  36nMAssay Description:In vitro effective concentration tested on HEK293 cells co-transfected with rat Dopamine receptor D4 using FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM55121(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Affinity DataEC50:  18nMAssay Description:In vitro effective concentration tested on HEK293 cells co-transfected with human Dopamine receptor D2 using FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetD(4) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50001955((-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]qu...)
Affinity DataEC50:  4.30nMAssay Description:In vitro effective concentration tested on HEK293 cells co-transfected with human Dopamine receptor D4 using FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetD(4) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150148(2-(4-Pyrimidin-2-yl-piperazin-1-ylmethyl)-1H-benzo...)
Affinity DataEC50:  44.8nMAssay Description:In vitro EC50 tested on HEK293 cells co-transfected with human Dopamine receptor D4.4 using FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(RAT)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM55121(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Affinity DataEC50:  2.40nMAssay Description:In vitro effective concentration tested on HEK293 cells co-transfected with rat Dopamine receptor D4 using FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150136(1'-(1H-Benzoimidazol-2-ylmethyl)-1',2',3',4',5',6'...)
Affinity DataEC50:  14nMAssay Description:In vitro EC50 tested on HEK293 cells co-transfected with human Dopamine receptor D4.4 using FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150135(2-[4-(3-Methanesulfonyl-pyridin-2-yl)-piperazin-1-...)
Affinity DataEC50:  136nMAssay Description:In vitro EC50 tested on HEK293 cells co-transfected with human Dopamine receptor D4.4 using FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50145073(5-Fluoro-2-(4-pyridin-2-yl-piperazin-1-ylmethyl)-1...)
Affinity DataEC50:  55nMAssay Description:In vitro effective concentration tested on HEK293 cells co-transfected with rat Dopamine receptor D2 using FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50145079(2-(4-Phenyl-piperazin-1-ylmethyl)-1H-benzoimidazol...)
Affinity DataEC50:  30.6nMAssay Description:In vitro EC50 tested on HEK293 cells co-transfected with human Dopamine receptor D4.4 using FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150155(4,6-Dibromo-2-(4-pyridin-2-yl-piperazin-1-ylmethyl...)
Affinity DataEC50:  416nMAssay Description:In vitro EC50 tested on HEK293 cells co-transfected with human Dopamine receptor D4.4 using FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 60 total ) | Next | Last >>
Jump to: