TargetProtein-serine O-palmitoleoyltransferase porcupine(Mus musculus)
Soochow University
Curated by ChEMBL
Soochow University
Curated by ChEMBL
Affinity DataIC50: 0.720nMAssay Description:Inhibition of porcupine in mouse L Wnt3A cells co-cultured with HEK293 cells assessed as suppression of Wnt signaling after 48 hrs by Super-top flash...More data for this Ligand-Target Pair
TargetProtein-serine O-palmitoleoyltransferase porcupine(Mus musculus)
Soochow University
Curated by ChEMBL
Soochow University
Curated by ChEMBL
Affinity DataIC50: 0.900nMAssay Description:Inhibition of porcupine in mouse L Wnt3A cells co-cultured with HEK293 cells assessed as suppression of Wnt signaling after 48 hrs by Super-top flash...More data for this Ligand-Target Pair
TargetProtein-serine O-palmitoleoyltransferase porcupine(Mus musculus)
Soochow University
Curated by ChEMBL
Soochow University
Curated by ChEMBL
Affinity DataIC50: 1.90nMAssay Description:Inhibition of porcupine in mouse L Wnt3A cells co-cultured with HEK293 cells assessed as suppression of Wnt signaling after 48 hrs by Super-top flash...More data for this Ligand-Target Pair
TargetProtein-serine O-palmitoleoyltransferase porcupine(Mus musculus)
Soochow University
Curated by ChEMBL
Soochow University
Curated by ChEMBL
Affinity DataIC50: 2.10nMAssay Description:Inhibition of porcupine in mouse L Wnt3A cells co-cultured with HEK293 cells assessed as suppression of Wnt signaling after 48 hrs by Super-top flash...More data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of smo-mediated hedgehog signaling pathway in mouse NIH3T3 cells expressing GRE-Luc reporter gene assessed as inhibition of SAG-induced GR...More data for this Ligand-Target Pair
TargetProtein-serine O-palmitoleoyltransferase porcupine(Mus musculus)
Soochow University
Curated by ChEMBL
Soochow University
Curated by ChEMBL
Affinity DataIC50: 6.5nMAssay Description:Inhibition of porcupine in mouse L Wnt3A cells co-cultured with HEK293 cells assessed as suppression of Wnt signaling after 48 hrs by Super-top flash...More data for this Ligand-Target Pair
Affinity DataIC50: 71nMAssay Description:Inhibition of smo-mediated hedgehog signaling pathway in mouse NIH3T3 cells expressing GRE-Luc reporter gene assessed as inhibition of SAG-induced GR...More data for this Ligand-Target Pair
Affinity DataIC50: 1.22E+3nMAssay Description:Inhibition of smo-mediated hedgehog signaling pathway in mouse NIH3T3 cells expressing GRE-Luc reporter gene assessed as inhibition of SAG-induced GR...More data for this Ligand-Target Pair
Affinity DataIC50: 3.66E+3nMAssay Description:Inhibition of smo-mediated hedgehog signaling pathway in mouse NIH3T3 cells expressing GRE-Luc reporter gene assessed as inhibition of SAG-induced GR...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Bodipy-cyclopamine binding to human Smo expressed in human U2OS cells after 2 hrs by high content fluorescence imaging analysisMore data for this Ligand-Target Pair