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Found 9 Enz. Inhib. hit(s) with all data for entry = 50002100
TargetArginase-2, mitochondrial(Homo sapiens (Human))TBA
LigandPNGBDBM50008099(CHEMBL1234777)
Affinity DataKi:  51nMAssay Description:Inhibition of arginase 2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgrammed cell death protein 1(Homo sapiens)TBA
LigandPNGBDBM50453464(CHEMBL4205401)
Affinity DataIC50: <50nMAssay Description:Inhibition of His-tagged PD-L1 binding to PD-1-Ig (unknown origin) preincubated with PD-L1 for 15 mins followed by PD-1-Ig addition measured after 15...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50453462(CHEMBL4214886)
Affinity DataIC50: <50nMAssay Description:Inhibition of N-terminal GST-tagged human HPK1 (1 to 346 residues) after 30 mins in presence of ATP by indirect ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgrammed cell death protein 1(Homo sapiens)TBA
LigandPNGBDBM365922(4-{[({2,6-dimethoxy-4- [(2-methyl-3-phenylphenyl) ...)
Affinity DataIC50: <50nMAssay Description:Inhibition of His-tagged PD-L1 binding to PD-1-Ig (unknown origin) preincubated with PD-L1 for 15 mins followed by PD-1-Ig addition measured after 15...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50453461(CHEMBL4213767)
Affinity DataIC50: <50nMAssay Description:Inhibition of N-terminal GST-tagged human HPK1 (1 to 346 residues) after 30 mins in presence of ATP by indirect ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))TBA
LigandPNGBDBM50453463(CHEMBL4205481)
Affinity DataIC50:  100nMAssay Description:Inhibition of N-terminal GST-tagged human SYK expressed in baculovirus infected Sf9 insect cells using Biotin-Aha-Aha-KEDPDYEWPSAKK as substrate afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargeteIF-2-alpha kinase GCN2(Homo sapiens (Human))TBA
LigandPNGBDBM50453465(CHEMBL4207945)
Affinity DataIC50: <300nMAssay Description:Inhibition of GCN2 (unknown origin) using GFP--fused eIF2alpha as substrate preincubated for 20 mins followed by substrate and ATP addition measured ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargeteIF-2-alpha kinase GCN2(Homo sapiens (Human))TBA
LigandPNGBDBM50453463(CHEMBL4205481)
Affinity DataIC50:  300nMAssay Description:Inhibition of GCN2 (unknown origin) using GFP--fused eIF2alpha as substrate preincubated for 20 mins followed by substrate and ATP addition measured ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetArginase-1(Homo sapiens (Human))TBA
LigandPNGBDBM50008099(CHEMBL1234777)
Affinity DataKd:  47nMAssay Description:Binding affinity to arginase 1 (unknown origin)More data for this Ligand-Target Pair