Affinity DataIC50: 3nMAssay Description:Inhibition of FDPS (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of FDPS (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of FDPS (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 24nMAssay Description:Inhibition of FDPS (unknown origin) using [14C] IPP and GPP as substrate preincubated for 10 mins followed by substrate addition and measured after 3...More data for this Ligand-Target Pair
Affinity DataIC50: 150nMAssay Description:Inhibition of FDPS (unknown origin) using [14C] IPP and GPP as substrate preincubated for 10 mins followed by substrate addition and measured after 3...More data for this Ligand-Target Pair
Affinity DataIC50: 690nMAssay Description:Inhibition of FDPS (unknown origin) using [14C] IPP and GPP as substrate preincubated for 10 mins followed by substrate addition and measured after 3...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of FDPS (unknown origin) using [14C] IPP and GPP as substrate preincubated for 10 mins followed by substrate addition and measured after 3...More data for this Ligand-Target Pair
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
University Of Iowa
Curated by ChEMBL
University Of Iowa
Curated by ChEMBL
Affinity DataIC50: 2.05E+4nMAssay Description:Inhibition of GGDPS (unknown origin) using [14C] IPP and FPP as substrate preincubated for 10 mins followed by substrate addition and measured after ...More data for this Ligand-Target Pair
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
University Of Iowa
Curated by ChEMBL
University Of Iowa
Curated by ChEMBL
Affinity DataIC50: 4.10E+4nMAssay Description:Inhibition of GGDPS (unknown origin) using [14C] IPP and FPP as substrate preincubated for 10 mins followed by substrate addition and measured after ...More data for this Ligand-Target Pair
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
University Of Iowa
Curated by ChEMBL
University Of Iowa
Curated by ChEMBL
Affinity DataIC50: 8.70E+4nMAssay Description:Inhibition of GGDPS (unknown origin) using [14C] IPP and FPP as substrate preincubated for 10 mins followed by substrate addition and measured after ...More data for this Ligand-Target Pair
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
University Of Iowa
Curated by ChEMBL
University Of Iowa
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of GGDPS (unknown origin) using [14C] IPP and FPP as substrate preincubated for 10 mins followed by substrate addition and measured after ...More data for this Ligand-Target Pair
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
University Of Iowa
Curated by ChEMBL
University Of Iowa
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of GGDPS (unknown origin) using [14C] IPP and FPP as substrate preincubated for 10 mins followed by substrate addition and measured after ...More data for this Ligand-Target Pair
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
University Of Iowa
Curated by ChEMBL
University Of Iowa
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of GGDPS (unknown origin) using [14C] IPP and FPP as substrate preincubated for 10 mins followed by substrate addition and measured after ...More data for this Ligand-Target Pair
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
University Of Iowa
Curated by ChEMBL
University Of Iowa
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of GGDPS (unknown origin) using [14C] IPP and FPP as substrate preincubated for 10 mins followed by substrate addition and measured after ...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of FDPS (unknown origin) using [14C] IPP and GPP as substrate preincubated for 10 mins followed by substrate addition and measured after 3...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of FDPS (unknown origin) using [14C] IPP and GPP as substrate preincubated for 10 mins followed by substrate addition and measured after 3...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of FDPS (unknown origin) using [14C] IPP and GPP as substrate preincubated for 10 mins followed by substrate addition and measured after 3...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of FDPS (unknown origin) using [14C] IPP and GPP as substrate preincubated for 10 mins followed by substrate addition and measured after 3...More data for this Ligand-Target Pair
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
University Of Iowa
Curated by ChEMBL
University Of Iowa
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of GGDPS (unknown origin) using [14C] IPP and FPP as substrate preincubated for 10 mins followed by substrate addition and measured after ...More data for this Ligand-Target Pair
TargetGeranylgeranyl transferase type-1 subunit beta(Rattus norvegicus)
University Of Iowa
Curated by ChEMBL
University Of Iowa
Curated by ChEMBL
Affinity DataIC50: 1.22E+5nMAssay Description:Inhibition of recombinant rat GGtase-1 expressed in Escherichia coli using dansyl-GCVLL as substrate after 1.5 hrs by spectrofluorimetric analysisMore data for this Ligand-Target Pair
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Rattus norvegicus)
University Of Iowa
Curated by ChEMBL
University Of Iowa
Curated by ChEMBL
Affinity DataIC50: 1.25E+5nMAssay Description:Inhibition of recombinant rat FTase expressed in Escherichia coli using dansyl-GCVLS as substrate after 1.5 hrs by spectrofluorimetric analysisMore data for this Ligand-Target Pair
TargetGeranylgeranyl transferase type-1 subunit beta(Rattus norvegicus)
University Of Iowa
Curated by ChEMBL
University Of Iowa
Curated by ChEMBL
Affinity DataIC50: 1.45E+5nMAssay Description:Inhibition of recombinant rat GGtase-1 expressed in Escherichia coli using dansyl-GCVLL as substrate after 1.5 hrs by spectrofluorimetric analysisMore data for this Ligand-Target Pair
TargetGeranylgeranyl transferase type-2 subunit alpha(Rattus norvegicus)
University Of Iowa
Curated by ChEMBL
University Of Iowa
Curated by ChEMBL
Affinity DataIC50: 1.98E+5nMAssay Description:Inhibition of recombinant rat RabGGTase expressed in Escherichia coli using Rab7 as substrate and [3H]geranylgeranyl pyrophosphate after 20 mins by l...More data for this Ligand-Target Pair
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Rattus norvegicus)
University Of Iowa
Curated by ChEMBL
University Of Iowa
Curated by ChEMBL
Affinity DataIC50: 3.40E+5nMAssay Description:Inhibition of recombinant rat FTase expressed in Escherichia coli using dansyl-GCVLS as substrate after 1.5 hrs by spectrofluorimetric analysisMore data for this Ligand-Target Pair
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Rattus norvegicus)
University Of Iowa
Curated by ChEMBL
University Of Iowa
Curated by ChEMBL
Affinity DataIC50: 4.50E+5nMAssay Description:Inhibition of recombinant rat FTase expressed in Escherichia coli using dansyl-GCVLS as substrate after 1.5 hrs by spectrofluorimetric analysisMore data for this Ligand-Target Pair
TargetGeranylgeranyl transferase type-2 subunit alpha(Rattus norvegicus)
University Of Iowa
Curated by ChEMBL
University Of Iowa
Curated by ChEMBL
Affinity DataIC50: 5.34E+5nMAssay Description:Inhibition of recombinant rat RabGGTase expressed in Escherichia coli using Rab7 as substrate and [3H]geranylgeranyl pyrophosphate after 20 mins by l...More data for this Ligand-Target Pair
TargetGeranylgeranyl transferase type-2 subunit alpha(Rattus norvegicus)
University Of Iowa
Curated by ChEMBL
University Of Iowa
Curated by ChEMBL
Affinity DataIC50: 7.38E+5nMAssay Description:Inhibition of recombinant rat RabGGTase expressed in Escherichia coli using Rab7 as substrate and [3H]geranylgeranyl pyrophosphate after 20 mins by l...More data for this Ligand-Target Pair
TargetGeranylgeranyl transferase type-2 subunit alpha/beta(Rattus norvegicus)
University Of Iowa
Curated by ChEMBL
University Of Iowa
Curated by ChEMBL
Affinity DataIC50: 8.10E+5nMAssay Description:Inhibition of recombinant rat RabGGTase expressed in Escherichia coli using Rab7 as substrate and [3H]geranylgeranyl pyrophosphate after 20 mins by l...More data for this Ligand-Target Pair
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Rattus norvegicus)
University Of Iowa
Curated by ChEMBL
University Of Iowa
Curated by ChEMBL
Affinity DataIC50: 8.30E+5nMAssay Description:Inhibition of recombinant rat FTase expressed in Escherichia coli using dansyl-GCVLS as substrate after 1.5 hrs by spectrofluorimetric analysisMore data for this Ligand-Target Pair
TargetGeranylgeranyl transferase type-2 subunit alpha(Rattus norvegicus)
University Of Iowa
Curated by ChEMBL
University Of Iowa
Curated by ChEMBL
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of recombinant rat RabGGTase expressed in Escherichia coli using Rab7 as substrate and [3H]geranylgeranyl pyrophosphate after 20 mins by l...More data for this Ligand-Target Pair
TargetGeranylgeranyl transferase type-1 subunit beta(Rattus norvegicus)
University Of Iowa
Curated by ChEMBL
University Of Iowa
Curated by ChEMBL
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of recombinant rat GGtase-1 expressed in Escherichia coli using dansyl-GCVLL as substrate after 1.5 hrs by spectrofluorimetric analysisMore data for this Ligand-Target Pair
TargetGeranylgeranyl transferase type-1 subunit beta(Rattus norvegicus)
University Of Iowa
Curated by ChEMBL
University Of Iowa
Curated by ChEMBL
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of recombinant rat GGtase-1 expressed in Escherichia coli using dansyl-GCVLL as substrate after 1.5 hrs by spectrofluorimetric analysisMore data for this Ligand-Target Pair
TargetGeranylgeranyl transferase type-1 subunit beta(Rattus norvegicus)
University Of Iowa
Curated by ChEMBL
University Of Iowa
Curated by ChEMBL
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of recombinant rat GGtase-1 expressed in Escherichia coli using dansyl-GCVLL as substrate after 1.5 hrs by spectrofluorimetric analysisMore data for this Ligand-Target Pair
TargetGeranylgeranyl transferase type-1 subunit beta(Rattus norvegicus)
University Of Iowa
Curated by ChEMBL
University Of Iowa
Curated by ChEMBL
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of recombinant rat GGtase-1 expressed in Escherichia coli using dansyl-GCVLL as substrate after 1.5 hrs by spectrofluorimetric analysisMore data for this Ligand-Target Pair
TargetGeranylgeranyl transferase type-2 subunit alpha(Rattus norvegicus)
University Of Iowa
Curated by ChEMBL
University Of Iowa
Curated by ChEMBL
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of recombinant rat RabGGTase expressed in Escherichia coli using Rab7 as substrate and [3H]geranylgeranyl pyrophosphate after 20 mins by l...More data for this Ligand-Target Pair
TargetGeranylgeranyl transferase type-2 subunit alpha(Rattus norvegicus)
University Of Iowa
Curated by ChEMBL
University Of Iowa
Curated by ChEMBL
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of recombinant rat RabGGTase expressed in Escherichia coli using Rab7 as substrate and [3H]geranylgeranyl pyrophosphate after 20 mins by l...More data for this Ligand-Target Pair
TargetGeranylgeranyl transferase type-1 subunit beta(Rattus norvegicus)
University Of Iowa
Curated by ChEMBL
University Of Iowa
Curated by ChEMBL
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of recombinant rat GGtase-1 expressed in Escherichia coli using dansyl-GCVLL as substrate after 1.5 hrs by spectrofluorimetric analysisMore data for this Ligand-Target Pair
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Rattus norvegicus)
University Of Iowa
Curated by ChEMBL
University Of Iowa
Curated by ChEMBL
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of recombinant rat FTase expressed in Escherichia coli using dansyl-GCVLS as substrate after 1.5 hrs by spectrofluorimetric analysisMore data for this Ligand-Target Pair
TargetGeranylgeranyl transferase type-1 subunit beta(Rattus norvegicus)
University Of Iowa
Curated by ChEMBL
University Of Iowa
Curated by ChEMBL
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of recombinant rat GGtase-1 expressed in Escherichia coli using dansyl-GCVLL as substrate after 1.5 hrs by spectrofluorimetric analysisMore data for this Ligand-Target Pair
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Rattus norvegicus)
University Of Iowa
Curated by ChEMBL
University Of Iowa
Curated by ChEMBL
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of recombinant rat FTase expressed in Escherichia coli using dansyl-GCVLS as substrate after 1.5 hrs by spectrofluorimetric analysisMore data for this Ligand-Target Pair
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Rattus norvegicus)
University Of Iowa
Curated by ChEMBL
University Of Iowa
Curated by ChEMBL
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of recombinant rat FTase expressed in Escherichia coli using dansyl-GCVLS as substrate after 1.5 hrs by spectrofluorimetric analysisMore data for this Ligand-Target Pair
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Rattus norvegicus)
University Of Iowa
Curated by ChEMBL
University Of Iowa
Curated by ChEMBL
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of recombinant rat FTase expressed in Escherichia coli using dansyl-GCVLS as substrate after 1.5 hrs by spectrofluorimetric analysisMore data for this Ligand-Target Pair
TargetGeranylgeranyl transferase type-2 subunit alpha(Rattus norvegicus)
University Of Iowa
Curated by ChEMBL
University Of Iowa
Curated by ChEMBL
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of recombinant rat RabGGTase expressed in Escherichia coli using Rab7 as substrate and [3H]geranylgeranyl pyrophosphate after 20 mins by l...More data for this Ligand-Target Pair