Compile Data Set for Download or QSAR
maximum 50k data
Found 43 Enz. Inhib. hit(s) with all data for entry = 50006919
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University Of Iowa

Curated by ChEMBL
LigandPNGBDBM25308((1-hydroxy-2-{imidazo[1,2-a]pyridin-3-yl}-1-phosph...)
Affinity DataIC50:  3nMAssay Description:Inhibition of FDPS (unknown origin)More data for this Ligand-Target Pair
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University Of Iowa

Curated by ChEMBL
LigandPNGBDBM12578(2-(imidazol-1-yl)-1-hydroxyethylidene-1,1-bisphosp...)
Affinity DataIC50:  3nMAssay Description:Inhibition of FDPS (unknown origin)More data for this Ligand-Target Pair
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University Of Iowa

Curated by ChEMBL
LigandPNGBDBM12576(Bisphosphonate 1 | CHEMBL923 | JMC515594 Compound ...)
Affinity DataIC50:  10nMAssay Description:Inhibition of FDPS (unknown origin)More data for this Ligand-Target Pair
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University Of Iowa

Curated by ChEMBL
LigandPNGBDBM50273716(CHEMBL457423 | [2-(Benzoimidazol-1-yl)ethyl]-bisph...)
Affinity DataIC50:  24nMAssay Description:Inhibition of FDPS (unknown origin) using [14C] IPP and GPP as substrate preincubated for 10 mins followed by substrate addition and measured after 3...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University Of Iowa

Curated by ChEMBL
LigandPNGBDBM50504717(CHEMBL4459281)
Affinity DataIC50:  150nMAssay Description:Inhibition of FDPS (unknown origin) using [14C] IPP and GPP as substrate preincubated for 10 mins followed by substrate addition and measured after 3...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University Of Iowa

Curated by ChEMBL
LigandPNGBDBM50504720(CHEMBL4529809)
Affinity DataIC50:  690nMAssay Description:Inhibition of FDPS (unknown origin) using [14C] IPP and GPP as substrate preincubated for 10 mins followed by substrate addition and measured after 3...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University Of Iowa

Curated by ChEMBL
LigandPNGBDBM50504716(CHEMBL4589567)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of FDPS (unknown origin) using [14C] IPP and GPP as substrate preincubated for 10 mins followed by substrate addition and measured after 3...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
University Of Iowa

Curated by ChEMBL
LigandPNGBDBM50273716(CHEMBL457423 | [2-(Benzoimidazol-1-yl)ethyl]-bisph...)
Affinity DataIC50:  2.05E+4nMAssay Description:Inhibition of GGDPS (unknown origin) using [14C] IPP and FPP as substrate preincubated for 10 mins followed by substrate addition and measured after ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
University Of Iowa

Curated by ChEMBL
LigandPNGBDBM50504720(CHEMBL4529809)
Affinity DataIC50:  4.10E+4nMAssay Description:Inhibition of GGDPS (unknown origin) using [14C] IPP and FPP as substrate preincubated for 10 mins followed by substrate addition and measured after ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
University Of Iowa

Curated by ChEMBL
LigandPNGBDBM50504717(CHEMBL4459281)
Affinity DataIC50:  8.70E+4nMAssay Description:Inhibition of GGDPS (unknown origin) using [14C] IPP and FPP as substrate preincubated for 10 mins followed by substrate addition and measured after ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
University Of Iowa

Curated by ChEMBL
LigandPNGBDBM50504716(CHEMBL4589567)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of GGDPS (unknown origin) using [14C] IPP and FPP as substrate preincubated for 10 mins followed by substrate addition and measured after ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
University Of Iowa

Curated by ChEMBL
LigandPNGBDBM50504718(CHEMBL4564870)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of GGDPS (unknown origin) using [14C] IPP and FPP as substrate preincubated for 10 mins followed by substrate addition and measured after ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
University Of Iowa

Curated by ChEMBL
LigandPNGBDBM50504715(CHEMBL4514446)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of GGDPS (unknown origin) using [14C] IPP and FPP as substrate preincubated for 10 mins followed by substrate addition and measured after ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
University Of Iowa

Curated by ChEMBL
LigandPNGBDBM50504719(CHEMBL4438314)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of GGDPS (unknown origin) using [14C] IPP and FPP as substrate preincubated for 10 mins followed by substrate addition and measured after ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University Of Iowa

Curated by ChEMBL
LigandPNGBDBM50504714(CHEMBL4460301)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of FDPS (unknown origin) using [14C] IPP and GPP as substrate preincubated for 10 mins followed by substrate addition and measured after 3...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University Of Iowa

Curated by ChEMBL
LigandPNGBDBM50504715(CHEMBL4514446)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of FDPS (unknown origin) using [14C] IPP and GPP as substrate preincubated for 10 mins followed by substrate addition and measured after 3...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University Of Iowa

Curated by ChEMBL
LigandPNGBDBM50504719(CHEMBL4438314)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of FDPS (unknown origin) using [14C] IPP and GPP as substrate preincubated for 10 mins followed by substrate addition and measured after 3...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University Of Iowa

Curated by ChEMBL
LigandPNGBDBM50504718(CHEMBL4564870)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of FDPS (unknown origin) using [14C] IPP and GPP as substrate preincubated for 10 mins followed by substrate addition and measured after 3...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
University Of Iowa

Curated by ChEMBL
LigandPNGBDBM50504714(CHEMBL4460301)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of GGDPS (unknown origin) using [14C] IPP and FPP as substrate preincubated for 10 mins followed by substrate addition and measured after ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGeranylgeranyl transferase type-1 subunit beta(Rattus norvegicus)
University Of Iowa

Curated by ChEMBL
LigandPNGBDBM50504717(CHEMBL4459281)
Affinity DataIC50:  1.22E+5nMAssay Description:Inhibition of recombinant rat GGtase-1 expressed in Escherichia coli using dansyl-GCVLL as substrate after 1.5 hrs by spectrofluorimetric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50504719(CHEMBL4438314)
Affinity DataIC50:  1.25E+5nMAssay Description:Inhibition of recombinant rat FTase expressed in Escherichia coli using dansyl-GCVLS as substrate after 1.5 hrs by spectrofluorimetric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGeranylgeranyl transferase type-1 subunit beta(Rattus norvegicus)
University Of Iowa

Curated by ChEMBL
LigandPNGBDBM50504718(CHEMBL4564870)
Affinity DataIC50:  1.45E+5nMAssay Description:Inhibition of recombinant rat GGtase-1 expressed in Escherichia coli using dansyl-GCVLL as substrate after 1.5 hrs by spectrofluorimetric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGeranylgeranyl transferase type-2 subunit alpha(Rattus norvegicus)
University Of Iowa

Curated by ChEMBL
LigandPNGBDBM50504719(CHEMBL4438314)
Affinity DataIC50:  1.98E+5nMAssay Description:Inhibition of recombinant rat RabGGTase expressed in Escherichia coli using Rab7 as substrate and [3H]geranylgeranyl pyrophosphate after 20 mins by l...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50504717(CHEMBL4459281)
Affinity DataIC50:  3.40E+5nMAssay Description:Inhibition of recombinant rat FTase expressed in Escherichia coli using dansyl-GCVLS as substrate after 1.5 hrs by spectrofluorimetric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50504718(CHEMBL4564870)
Affinity DataIC50:  4.50E+5nMAssay Description:Inhibition of recombinant rat FTase expressed in Escherichia coli using dansyl-GCVLS as substrate after 1.5 hrs by spectrofluorimetric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGeranylgeranyl transferase type-2 subunit alpha(Rattus norvegicus)
University Of Iowa

Curated by ChEMBL
LigandPNGBDBM50504720(CHEMBL4529809)
Affinity DataIC50:  5.34E+5nMAssay Description:Inhibition of recombinant rat RabGGTase expressed in Escherichia coli using Rab7 as substrate and [3H]geranylgeranyl pyrophosphate after 20 mins by l...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGeranylgeranyl transferase type-2 subunit alpha(Rattus norvegicus)
University Of Iowa

Curated by ChEMBL
LigandPNGBDBM50504717(CHEMBL4459281)
Affinity DataIC50:  7.38E+5nMAssay Description:Inhibition of recombinant rat RabGGTase expressed in Escherichia coli using Rab7 as substrate and [3H]geranylgeranyl pyrophosphate after 20 mins by l...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGeranylgeranyl transferase type-2 subunit alpha/beta(Rattus norvegicus)
University Of Iowa

Curated by ChEMBL
LigandPNGBDBM50504715(CHEMBL4514446)
Affinity DataIC50:  8.10E+5nMAssay Description:Inhibition of recombinant rat RabGGTase expressed in Escherichia coli using Rab7 as substrate and [3H]geranylgeranyl pyrophosphate after 20 mins by l...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50273716(CHEMBL457423 | [2-(Benzoimidazol-1-yl)ethyl]-bisph...)
Affinity DataIC50:  8.30E+5nMAssay Description:Inhibition of recombinant rat FTase expressed in Escherichia coli using dansyl-GCVLS as substrate after 1.5 hrs by spectrofluorimetric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGeranylgeranyl transferase type-2 subunit alpha(Rattus norvegicus)
University Of Iowa

Curated by ChEMBL
LigandPNGBDBM50273716(CHEMBL457423 | [2-(Benzoimidazol-1-yl)ethyl]-bisph...)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of recombinant rat RabGGTase expressed in Escherichia coli using Rab7 as substrate and [3H]geranylgeranyl pyrophosphate after 20 mins by l...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGeranylgeranyl transferase type-1 subunit beta(Rattus norvegicus)
University Of Iowa

Curated by ChEMBL
LigandPNGBDBM50504716(CHEMBL4589567)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of recombinant rat GGtase-1 expressed in Escherichia coli using dansyl-GCVLL as substrate after 1.5 hrs by spectrofluorimetric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGeranylgeranyl transferase type-1 subunit beta(Rattus norvegicus)
University Of Iowa

Curated by ChEMBL
LigandPNGBDBM50273716(CHEMBL457423 | [2-(Benzoimidazol-1-yl)ethyl]-bisph...)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of recombinant rat GGtase-1 expressed in Escherichia coli using dansyl-GCVLL as substrate after 1.5 hrs by spectrofluorimetric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGeranylgeranyl transferase type-1 subunit beta(Rattus norvegicus)
University Of Iowa

Curated by ChEMBL
LigandPNGBDBM50504719(CHEMBL4438314)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of recombinant rat GGtase-1 expressed in Escherichia coli using dansyl-GCVLL as substrate after 1.5 hrs by spectrofluorimetric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGeranylgeranyl transferase type-1 subunit beta(Rattus norvegicus)
University Of Iowa

Curated by ChEMBL
LigandPNGBDBM50504720(CHEMBL4529809)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of recombinant rat GGtase-1 expressed in Escherichia coli using dansyl-GCVLL as substrate after 1.5 hrs by spectrofluorimetric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGeranylgeranyl transferase type-2 subunit alpha(Rattus norvegicus)
University Of Iowa

Curated by ChEMBL
LigandPNGBDBM50504714(CHEMBL4460301)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of recombinant rat RabGGTase expressed in Escherichia coli using Rab7 as substrate and [3H]geranylgeranyl pyrophosphate after 20 mins by l...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGeranylgeranyl transferase type-2 subunit alpha(Rattus norvegicus)
University Of Iowa

Curated by ChEMBL
LigandPNGBDBM50504718(CHEMBL4564870)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of recombinant rat RabGGTase expressed in Escherichia coli using Rab7 as substrate and [3H]geranylgeranyl pyrophosphate after 20 mins by l...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGeranylgeranyl transferase type-1 subunit beta(Rattus norvegicus)
University Of Iowa

Curated by ChEMBL
LigandPNGBDBM50504715(CHEMBL4514446)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of recombinant rat GGtase-1 expressed in Escherichia coli using dansyl-GCVLL as substrate after 1.5 hrs by spectrofluorimetric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50504716(CHEMBL4589567)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of recombinant rat FTase expressed in Escherichia coli using dansyl-GCVLS as substrate after 1.5 hrs by spectrofluorimetric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGeranylgeranyl transferase type-1 subunit beta(Rattus norvegicus)
University Of Iowa

Curated by ChEMBL
LigandPNGBDBM50504714(CHEMBL4460301)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of recombinant rat GGtase-1 expressed in Escherichia coli using dansyl-GCVLL as substrate after 1.5 hrs by spectrofluorimetric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50504715(CHEMBL4514446)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of recombinant rat FTase expressed in Escherichia coli using dansyl-GCVLS as substrate after 1.5 hrs by spectrofluorimetric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50504720(CHEMBL4529809)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of recombinant rat FTase expressed in Escherichia coli using dansyl-GCVLS as substrate after 1.5 hrs by spectrofluorimetric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50504714(CHEMBL4460301)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of recombinant rat FTase expressed in Escherichia coli using dansyl-GCVLS as substrate after 1.5 hrs by spectrofluorimetric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGeranylgeranyl transferase type-2 subunit alpha(Rattus norvegicus)
University Of Iowa

Curated by ChEMBL
LigandPNGBDBM50504716(CHEMBL4589567)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of recombinant rat RabGGTase expressed in Escherichia coli using Rab7 as substrate and [3H]geranylgeranyl pyrophosphate after 20 mins by l...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed