Compile Data Set for Download or QSAR
maximum 50k data
Found 31 Enz. Inhib. hit(s) with all data for entry = 50012855
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
National Research Centre

Curated by ChEMBL
LigandPNGBDBM50428286(DABRAFENIB | GSK2118436A)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of BRAF V600E mutant (unknown origin)More data for this Ligand-Target Pair
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
National Research Centre

Curated by ChEMBL
LigandPNGBDBM13216(BMS-354825 | CHEMBL1421 | DASATINIB | N-(2-Chloro-...)
Affinity DataIC50:  1nMAssay Description:Inhibition of c-kit (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
National Research Centre

Curated by ChEMBL
LigandPNGBDBM13216(BMS-354825 | CHEMBL1421 | DASATINIB | N-(2-Chloro-...)
Affinity DataIC50:  1nMAssay Description:Inhibition of Src (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
National Research Centre

Curated by ChEMBL
LigandPNGBDBM13216(BMS-354825 | CHEMBL1421 | DASATINIB | N-(2-Chloro-...)
Affinity DataIC50:  1nMAssay Description:Inhibition of ABL (unknown origin)More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
National Research Centre

Curated by ChEMBL
LigandPNGBDBM5446(CHEMBL553 | ERLOTINIB HYDROCHLORIDE | Erlotinib | ...)
Affinity DataIC50:  2nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
National Research Centre

Curated by ChEMBL
LigandPNGBDBM112499(DACOMITINIB | US8623883, No. 2 | WO2022090481, Exa...)
Affinity DataIC50:  6nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
National Research Centre

Curated by ChEMBL
LigandPNGBDBM50322823((S)-N-(4-(3-chloro-4-fluorophenylamino)-7-(tetrahy...)
Affinity DataIC50:  10nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
National Research Centre

Curated by ChEMBL
LigandPNGBDBM5445(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Affinity DataIC50:  11nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
National Research Centre

Curated by ChEMBL
LigandPNGBDBM50029668(AZD-9291 | Osimertinib | US10085983, Compound AZD-...)
Affinity DataIC50:  13nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1/2(Homo sapiens (Human))
National Research Centre

Curated by ChEMBL
LigandPNGBDBM50355497(AZD-6244 | CHEMBL1614701)
Affinity DataIC50:  14nMAssay Description:Inhibition of MEK (unknown origin)More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
National Research Centre

Curated by ChEMBL
LigandPNGBDBM5447(CHEMBL939 | GEFITINIB | Iressa | N-(3-Chloro-4-flu...)
Affinity DataIC50:  37nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
National Research Centre

Curated by ChEMBL
LigandPNGBDBM50561030(CHEMBL4750734)
Affinity DataIC50:  72nMAssay Description:Inhibition of EGFR (unknown origin) using ATF-2 as substrate after 1 hr by radiometric based ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
National Research Centre

Curated by ChEMBL
LigandPNGBDBM50561024(CHEMBL4753631)
Affinity DataIC50:  85nMAssay Description:Inhibition of EGFR (unknown origin) using ATF-2 as substrate after 1 hr by radiometric based ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
National Research Centre

Curated by ChEMBL
LigandPNGBDBM50561025(CHEMBL4786168)
Affinity DataIC50:  104nMAssay Description:Inhibition of EGFR (unknown origin) using ATF-2 as substrate after 1 hr by radiometric based ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
National Research Centre

Curated by ChEMBL
LigandPNGBDBM50561017(CHEMBL4780058)
Affinity DataIC50:  110nMAssay Description:Inhibition of EGFR (unknown origin) using ATF-2 as substrate after 1 hr by radiometric based ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
National Research Centre

Curated by ChEMBL
LigandPNGBDBM50561020(CHEMBL4783948)
Affinity DataIC50:  150nMAssay Description:Inhibition of EGFR (unknown origin) using ATF-2 as substrate after 1 hr by radiometric based ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
National Research Centre

Curated by ChEMBL
LigandPNGBDBM5446(CHEMBL553 | ERLOTINIB HYDROCHLORIDE | Erlotinib | ...)
Affinity DataIC50:  153nMAssay Description:Inhibition of EGFR (unknown origin) using ATF-2 as substrate after 1 hr by radiometric based ELISAMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
National Research Centre

Curated by ChEMBL
LigandPNGBDBM50561022(CHEMBL4740646)
Affinity DataIC50:  208nMAssay Description:Inhibition of EGFR (unknown origin) using ATF-2 as substrate after 1 hr by radiometric based ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
National Research Centre

Curated by ChEMBL
LigandPNGBDBM50561029(CHEMBL4746023)
Affinity DataIC50:  213nMAssay Description:Inhibition of EGFR (unknown origin) using ATF-2 as substrate after 1 hr by radiometric based ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
National Research Centre

Curated by ChEMBL
LigandPNGBDBM50561026(CHEMBL4752843)
Affinity DataIC50:  254nMAssay Description:Inhibition of EGFR (unknown origin) using ATF-2 as substrate after 1 hr by radiometric based ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
National Research Centre

Curated by ChEMBL
LigandPNGBDBM50561018(CHEMBL4747759)
Affinity DataIC50:  279nMAssay Description:Inhibition of EGFR (unknown origin) using ATF-2 as substrate after 1 hr by radiometric based ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
National Research Centre

Curated by ChEMBL
LigandPNGBDBM50561021(CHEMBL4794131)
Affinity DataIC50:  312nMAssay Description:Inhibition of EGFR (unknown origin) using ATF-2 as substrate after 1 hr by radiometric based ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
National Research Centre

Curated by ChEMBL
LigandPNGBDBM50561032(CHEMBL4749518)
Affinity DataIC50:  342nMAssay Description:Inhibition of EGFR (unknown origin) using ATF-2 as substrate after 1 hr by radiometric based ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
National Research Centre

Curated by ChEMBL
LigandPNGBDBM50561027(CHEMBL4746321)
Affinity DataIC50:  406nMAssay Description:Inhibition of EGFR (unknown origin) using ATF-2 as substrate after 1 hr by radiometric based ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
National Research Centre

Curated by ChEMBL
LigandPNGBDBM50561028(CHEMBL4762604)
Affinity DataIC50:  514nMAssay Description:Inhibition of EGFR (unknown origin) using ATF-2 as substrate after 1 hr by radiometric based ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
National Research Centre

Curated by ChEMBL
LigandPNGBDBM50561033(CHEMBL4796408)
Affinity DataIC50:  569nMAssay Description:Inhibition of EGFR (unknown origin) using ATF-2 as substrate after 1 hr by radiometric based ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
National Research Centre

Curated by ChEMBL
LigandPNGBDBM50561023(CHEMBL4758204)
Affinity DataIC50:  623nMAssay Description:Inhibition of EGFR (unknown origin) using ATF-2 as substrate after 1 hr by radiometric based ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
National Research Centre

Curated by ChEMBL
LigandPNGBDBM50561031(CHEMBL4763960)
Affinity DataIC50:  773nMAssay Description:Inhibition of EGFR (unknown origin) using ATF-2 as substrate after 1 hr by radiometric based ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
National Research Centre

Curated by ChEMBL
LigandPNGBDBM50561019(CHEMBL4749342)
Affinity DataIC50:  1.24E+3nMAssay Description:Inhibition of EGFR (unknown origin) using ATF-2 as substrate after 1 hr by radiometric based ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
National Research Centre

Curated by ChEMBL
LigandPNGBDBM50561016(CHEMBL34922)
Affinity DataIC50:  3.00E+4nMAssay Description:Inhibition of Topoisomerase 2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
National Research Centre

Curated by ChEMBL
LigandPNGBDBM50561016(CHEMBL34922)
Affinity DataIC50:  3.00E+4nMAssay Description:Inhibition of Topoisomerase 1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed