Compile Data Set for Download or QSAR
maximum 50k data
Found 18 Enz. Inhib. hit(s) with all data for entry = 320
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
National Institutes of Health

LigandPNGBDBM499(6-hexyl-3-[(6-hexyl-4,7-dihydroxy-2-oxo-3,4-dihydr...)
Affinity DataIC50:  320nMpH: 6.5 T: 2°CAssay Description:Sensitivity of HIV-1 protease activity to protease inhibitors was determined by a peptide substrate cleavage assay. Protease products were analyzed o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
National Institutes of Health

LigandPNGBDBM502(2-({4-[bis(3-hydroxy-1,4-dioxo-1,4-dihydronaphthal...)
Affinity DataIC50:  750nMpH: 6.5 T: 2°CAssay Description:Sensitivity of HIV-1 protease activity to protease inhibitors was determined by a peptide substrate cleavage assay. Protease products were analyzed o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
National Institutes of Health

LigandPNGBDBM506(3-({4-[bis(4-hydroxy-2-oxo-2H-chromen-3-yl)methyl]...)
Affinity DataIC50:  1.70E+3nMpH: 6.5 T: 2°CAssay Description:Sensitivity of HIV-1 protease activity to protease inhibitors was determined by a peptide substrate cleavage assay. Protease products were analyzed o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
National Institutes of Health

LigandPNGBDBM510(11,12-dihydroxy-5,10-dioxo-4a,5,10,11,12,12a-hexah...)
Affinity DataIC50:  2.00E+3nMpH: 6.5 T: 2°CAssay Description:Sensitivity of HIV-1 protease activity to protease inhibitors was determined by a peptide substrate cleavage assay. Protease products were analyzed o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
National Institutes of Health

LigandPNGBDBM503(3-benzyl-4,5-dihydroxy-2H-chromen-2-one | CHEMBL64...)
Affinity DataIC50:  6.00E+3nMpH: 6.5 T: 2°CAssay Description:Sensitivity of HIV-1 protease activity to protease inhibitors was determined by a peptide substrate cleavage assay. Protease products were analyzed o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
National Institutes of Health

LigandPNGBDBM514(4-hydroxy-3,8-diphenyl-2H-chromen-2-one | Cancer C...)
Affinity DataIC50:  1.30E+4nMpH: 6.5 T: 2°CAssay Description:Sensitivity of HIV-1 protease activity to protease inhibitors was determined by a peptide substrate cleavage assay. Protease products were analyzed o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
National Institutes of Health

LigandPNGBDBM507(1,8a-dihydroxy-4a,5,6-trimethyl-decahydronaphthale...)
Affinity DataIC50:  1.60E+4nMpH: 6.5 T: 2°CAssay Description:Sensitivity of HIV-1 protease activity to protease inhibitors was determined by a peptide substrate cleavage assay. Protease products were analyzed o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
National Institutes of Health

LigandPNGBDBM511(2-{[(benzyloxy)carbonyl]amino}-2-(2-methylpropyl)p...)
Affinity DataIC50:  1.70E+4nMpH: 6.5 T: 2°CAssay Description:Sensitivity of HIV-1 protease activity to protease inhibitors was determined by a peptide substrate cleavage assay. Protease products were analyzed o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
National Institutes of Health

LigandPNGBDBM500(4-hydroxy-3-[(4-hydroxy-2-oxo-3,4-dihydro-2H-1-ben...)
Affinity DataIC50:  2.10E+4nMpH: 6.5 T: 2°CAssay Description:Sensitivity of HIV-1 protease activity to protease inhibitors was determined by a peptide substrate cleavage assay. Protease products were analyzed o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
National Institutes of Health

LigandPNGBDBM504(2-acetamido-2-(thiophen-3-ylmethyl)propanedioic ac...)
Affinity DataIC50:  2.30E+4nMpH: 6.5 T: 2°CAssay Description:Sensitivity of HIV-1 protease activity to protease inhibitors was determined by a peptide substrate cleavage assay. Protease products were analyzed o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
National Institutes of Health

LigandPNGBDBM508(2-[(2,4-dichlorophenyl)(3-hydroxy-1,4-dioxo-1,4-di...)
Affinity DataIC50:  2.40E+4nMpH: 6.5 T: 2°CAssay Description:Sensitivity of HIV-1 protease activity to protease inhibitors was determined by a peptide substrate cleavage assay. Protease products were analyzed o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
National Institutes of Health

LigandPNGBDBM512(2-butanoyl-6-[(3-butanoyl-2,4,6-trihydroxy-5-methy...)
Affinity DataIC50:  2.60E+4nMpH: 6.5 T: 2°CAssay Description:Sensitivity of HIV-1 protease activity to protease inhibitors was determined by a peptide substrate cleavage assay. Protease products were analyzed o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
National Institutes of Health

LigandPNGBDBM501(4-{2-[(1R,2R,10S,11R,14S,15S,17S)-14,17-dihydroxy-...)
Affinity DataIC50:  2.70E+4nMpH: 6.5 T: 2°CAssay Description:Sensitivity of HIV-1 protease activity to protease inhibitors was determined by a peptide substrate cleavage assay. Protease products were analyzed o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
National Institutes of Health

LigandPNGBDBM505(3-[2H-1,3-benzodioxol-5-yl(4-hydroxy-2-oxo-2H-chro...)
Affinity DataIC50:  3.00E+4nMpH: 6.5 T: 2°CAssay Description:Sensitivity of HIV-1 protease activity to protease inhibitors was determined by a peptide substrate cleavage assay. Protease products were analyzed o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
National Institutes of Health

LigandPNGBDBM516(CHEMBL62658 | N-[2,6-bis(propan-2-yl)phenyl]-6-(4-...)
Affinity DataIC50:  3.10E+4nMpH: 6.5 T: 2°CAssay Description:Sensitivity of HIV-1 protease activity to protease inhibitors was determined by a peptide substrate cleavage assay. Protease products were analyzed o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
National Institutes of Health

LigandPNGBDBM509(Cancer Chemotherapy National Service Center (CCNSC...)
Affinity DataIC50:  3.20E+4nMpH: 6.5 T: 2°CAssay Description:Sensitivity of HIV-1 protease activity to protease inhibitors was determined by a peptide substrate cleavage assay. Protease products were analyzed o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
National Institutes of Health

LigandPNGBDBM513((2S,3R,4R,4aS,6aR,6bR,8aS,12aS,14aS,14bR)-2,3-dihy...)
Affinity DataIC50:  3.50E+4nMpH: 6.5 T: 2°CAssay Description:Sensitivity of HIV-1 protease activity to protease inhibitors was determined by a peptide substrate cleavage assay. Protease products were analyzed o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
National Institutes of Health

LigandPNGBDBM515(4-hydroxy-3-phenyl-2H-chromen-2-one | Cancer Chemo...)
Affinity DataIC50:  4.20E+4nMpH: 6.5 T: 2°CAssay Description:Sensitivity of HIV-1 protease activity to protease inhibitors was determined by a peptide substrate cleavage assay. Protease products were analyzed o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed