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Found 57 Enz. Inhib. hit(s) with all data for assayid = 1 entry = 10370
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
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LigandPNGBDBM531233((Z)-Methyl 3-(((4-(4-(2-((2-hydroxyethyl)amino)-2-...)
Affinity DataKi:  7.90nMAssay Description:Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...More data for this Ligand-Target Pair
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LigandPNGBDBM445255(US10669235, Example 46 | US11208381, Example 46)
Affinity DataKi:  7.92nMAssay Description:Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...More data for this Ligand-Target Pair
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LigandPNGBDBM445246(US10669235, Example 37 | US11208381, Example 37)
Affinity DataKi:  8.56nMAssay Description:Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...More data for this Ligand-Target Pair
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LigandPNGBDBM445241(US10669235, Example 32 | US11208381, Example 32)
Affinity DataKi:  9.03nMAssay Description:Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...More data for this Ligand-Target Pair
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LigandPNGBDBM445247(US10669235, Example 38 | US11208381, Example 38)
Affinity DataKi:  9.73nMAssay Description:Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...More data for this Ligand-Target Pair
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LigandPNGBDBM445257(US10669235, Example 48 | US11208381, Example 48)
Affinity DataKi:  11.3nMAssay Description:Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...More data for this Ligand-Target Pair
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LigandPNGBDBM445228(US10669235, Example 19 | US11208381, Example 19)
Affinity DataKi:  13.6nMAssay Description:Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...More data for this Ligand-Target Pair
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LigandPNGBDBM445242(US10669235, Example 33 | US11208381, Example 33)
Affinity DataKi:  14.3nMAssay Description:Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...More data for this Ligand-Target Pair
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LigandPNGBDBM445240(US10669235, Example 31 | US11208381, Example 31)
Affinity DataKi:  15.3nMAssay Description:Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...More data for this Ligand-Target Pair
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LigandPNGBDBM445231(US10669235, Example 22 | US11208381, Example 22)
Affinity DataKi:  16.3nMAssay Description:Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...More data for this Ligand-Target Pair
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LigandPNGBDBM445226(US10669235, Example 17 | US11208381, Example 17)
Affinity DataKi:  16.6nMAssay Description:Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...More data for this Ligand-Target Pair
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LigandPNGBDBM445222(US10669235, Example 13 | US10669235, Example 49 | ...)
Affinity DataKi:  19.6nMAssay Description:Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...More data for this Ligand-Target Pair
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LigandPNGBDBM445222(US10669235, Example 13 | US10669235, Example 49 | ...)
Affinity DataKi:  19.6nMAssay Description:Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...More data for this Ligand-Target Pair
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LigandPNGBDBM445223(US10669235, Example 14 | US10669235, Example 50 | ...)
Affinity DataKi:  19.7nMAssay Description:Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...More data for this Ligand-Target Pair
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LigandPNGBDBM445223(US10669235, Example 14 | US10669235, Example 50 | ...)
Affinity DataKi:  19.7nMAssay Description:Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...More data for this Ligand-Target Pair
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LigandPNGBDBM445221(US10669235, Example 12 | US11208381, Example 12)
Affinity DataKi:  22.4nMAssay Description:Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...More data for this Ligand-Target Pair
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LigandPNGBDBM445234(US10669235, Example 25 | US11208381, Example 25)
Affinity DataKi:  23.5nMAssay Description:Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...More data for this Ligand-Target Pair
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LigandPNGBDBM445250(US10669235, Example 41 | US11208381, Example 41)
Affinity DataKi:  23.8nMAssay Description:Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...More data for this Ligand-Target Pair
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LigandPNGBDBM445220(US10669235, Example 11 | US11208381, Example 11)
Affinity DataKi:  23.9nMAssay Description:Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...More data for this Ligand-Target Pair
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LigandPNGBDBM445260(US10669235, Example 51 | US11208381, Example 51)
Affinity DataKi:  24.2nMAssay Description:Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...More data for this Ligand-Target Pair
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LigandPNGBDBM445262(US10669235, Example 53 | US11208381, Example 53)
Affinity DataKi:  25.2nMAssay Description:Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...More data for this Ligand-Target Pair
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LigandPNGBDBM445230(US10669235, Example 21 | US11208381, Example 21)
Affinity DataKi:  27.1nMAssay Description:Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...More data for this Ligand-Target Pair
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LigandPNGBDBM445238(US10669235, Example 29 | US11208381, Example 29)
Affinity DataKi:  27.6nMAssay Description:Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...More data for this Ligand-Target Pair
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LigandPNGBDBM445215(US10669235, Example 6 | US11208381, Example 6)
Affinity DataKi:  28.4nMAssay Description:Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...More data for this Ligand-Target Pair
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LigandPNGBDBM445213(US10669235, Example 4 | US11208381, Example 4)
Affinity DataKi:  29.3nMAssay Description:Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...More data for this Ligand-Target Pair
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LigandPNGBDBM50026612(BIBF-1120 | Nintedanib | US10981896, Compound Nint...)
Affinity DataKi:  32nMAssay Description:Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...More data for this Ligand-Target Pair
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LigandPNGBDBM445239(US10669235, Example 30 | US11208381, Example 30)
Affinity DataKi:  32.3nMAssay Description:Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...More data for this Ligand-Target Pair
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LigandPNGBDBM445251(US10669235, Example 42 | US11208381, Example 42)
Affinity DataKi:  33.8nMAssay Description:Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...More data for this Ligand-Target Pair
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LigandPNGBDBM445212(US10669235, Example 3 | US11208381, Example 3)
Affinity DataKi:  34.1nMAssay Description:Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...More data for this Ligand-Target Pair
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LigandPNGBDBM445216(US10669235, Example 7 | US11208381, Example 7)
Affinity DataKi:  35nMAssay Description:Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...More data for this Ligand-Target Pair
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LigandPNGBDBM531218((Z)-Methyl 5-methyl-3-(((4-(N-(2-(4-methylpiperazi...)
Affinity DataKi:  35nMAssay Description:Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...More data for this Ligand-Target Pair
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LigandPNGBDBM445227(US10669235, Example 18 | US11208381, Example 18)
Affinity DataKi:  36.6nMAssay Description:Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...More data for this Ligand-Target Pair
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LigandPNGBDBM445218(US10669235, Example 9 | US11208381, Example 9)
Affinity DataKi:  38.7nMAssay Description:Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...More data for this Ligand-Target Pair
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LigandPNGBDBM445265(US10669235, Example 56 | US11208381, Example 56)
Affinity DataKi:  39.8nMAssay Description:Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...More data for this Ligand-Target Pair
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LigandPNGBDBM445254(US10669235, Example 45 | US11208381, Example 45)
Affinity DataKi:  40.2nMAssay Description:Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...More data for this Ligand-Target Pair
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LigandPNGBDBM445217(US10669235, Example 8 | US11208381, Example 8)
Affinity DataKi:  41.8nMAssay Description:Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...More data for this Ligand-Target Pair
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LigandPNGBDBM445214(US10669235, Example 5 | US11208381, Example 5)
Affinity DataKi:  43.7nMAssay Description:Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...More data for this Ligand-Target Pair
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LigandPNGBDBM531219((Z)-Methyl 3-(((4-((2-(dimethylamino)ethyl)carbamo...)
Affinity DataKi:  44.9nMAssay Description:Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...More data for this Ligand-Target Pair
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LigandPNGBDBM445248(US10669235, Example 39 | US11208381, Example 39)
Affinity DataKi:  47.4nMAssay Description:Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...More data for this Ligand-Target Pair
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LigandPNGBDBM445229(US10669235, Example 20 | US11208381, Example 20)
Affinity DataKi:  48.5nMAssay Description:Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...More data for this Ligand-Target Pair
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LigandPNGBDBM445261(US10669235, Example 52 | US11208381, Example 52)
Affinity DataKi:  50.8nMAssay Description:Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...More data for this Ligand-Target Pair
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LigandPNGBDBM445225(US10669235, Example 16 | US11208381, Example 16)
Affinity DataKi:  57.9nMAssay Description:Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...More data for this Ligand-Target Pair
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LigandPNGBDBM445236(US10669235, Example 27 | US11208381, Example 27)
Affinity DataKi:  61nMAssay Description:Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...More data for this Ligand-Target Pair
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LigandPNGBDBM445233(US10669235, Example 24 | US11208381, Example 24)
Affinity DataKi:  65.2nMAssay Description:Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...More data for this Ligand-Target Pair
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LigandPNGBDBM445244(US10669235, Example 35 | US11208381, Example 35)
Affinity DataKi:  66.6nMAssay Description:Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...More data for this Ligand-Target Pair
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LigandPNGBDBM445245(US10669235, Example 36 | US11208381, Example 36)
Affinity DataKi:  71.9nMAssay Description:Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...More data for this Ligand-Target Pair
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LigandPNGBDBM445249(US10669235, Example 40 | US11208381, Example 40)
Affinity DataKi:  78.1nMAssay Description:Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...More data for this Ligand-Target Pair
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LigandPNGBDBM445264(US10669235, Example 55 | US11208381, Example 55)
Affinity DataKi:  79.4nMAssay Description:Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...More data for this Ligand-Target Pair
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LigandPNGBDBM445219(US10669235, Example 10 | US11208381, Example 10)
Affinity DataKi:  82.3nMAssay Description:Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...More data for this Ligand-Target Pair
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LigandPNGBDBM445243(US10669235, Example 34 | US11208381, Example 34)
Affinity DataKi:  98.8nMAssay Description:Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...More data for this Ligand-Target Pair
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