Compile Data Set for Download or QSAR
Found 12 Enz. Inhib. hit(s) with all data for assayid = 1 entry = 2344
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Purdue Pharma LP

US Patent
LigandPNGBDBM311147((S)-2-(4-((7-chloro-1-methyl-1H- indazol-4-yl)oxy)...)
Affinity DataIC50:  157nMAssay Description:In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN1, NE) of human Nav1.7 (Access...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Purdue Pharma LP

US Patent
LigandPNGBDBM311145((S)-2-(4-((7-fluoro-1-methyl-1H- indazol-4-yl)oxy)...)
Affinity DataIC50:  393nMAssay Description:In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN1, NE) of human Nav1.7 (Access...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Purdue Pharma LP

US Patent
LigandPNGBDBM311141((S)-2-(4-((7-chloro-1-methyl-1H- indazol-4-yl)oxy)...)
Affinity DataIC50:  405nMAssay Description:In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN1, NE) of human Nav1.7 (Access...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Purdue Pharma LP

US Patent
LigandPNGBDBM311148((S)-6-(4-((7-chloro-1-methyl-1H- indazol-4-yl)oxy)...)
Affinity DataIC50:  450nMAssay Description:In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN1, NE) of human Nav1.7 (Access...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Purdue Pharma LP

US Patent
LigandPNGBDBM311143(6-(4-((7-chloro-1-methyl-1H- indazol-4-yl)oxy)phen...)
Affinity DataIC50:  530nMAssay Description:In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN1, NE) of human Nav1.7 (Access...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Purdue Pharma LP

US Patent
LigandPNGBDBM311150((R)-4-(1,2-dihydroxyethyl)-6-(4- ((7-fluoro-1-meth...)
Affinity DataIC50:  596nMAssay Description:In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN1, NE) of human Nav1.7 (Access...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Purdue Pharma LP

US Patent
LigandPNGBDBM311144((S)-6-((1-amino-1-oxopropan-2- yl)amino)-2-(4-((7-...)
Affinity DataIC50:  601nMAssay Description:In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN1, NE) of human Nav1.7 (Access...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Purdue Pharma LP

US Patent
LigandPNGBDBM311142(2-(4-((7-chloro-1-methyl-1H- indazol-4-yl)oxy)phen...)
Affinity DataIC50:  718nMAssay Description:In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN1, NE) of human Nav1.7 (Access...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Purdue Pharma LP

US Patent
LigandPNGBDBM311149((S)-4-(1,2-dihydroxyethyl)-6-(4- ((7-fluoro-1-meth...)
Affinity DataIC50:  797nMAssay Description:In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN1, NE) of human Nav1.7 (Access...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Purdue Pharma LP

US Patent
LigandPNGBDBM311146((S)-2-(4-((1-methyl-1H-indazol- 4-yl)oxy)phenyl)-6...)
Affinity DataIC50:  2.24E+3nMAssay Description:In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN1, NE) of human Nav1.7 (Access...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Purdue Pharma LP

US Patent
LigandPNGBDBM311151(5-chloro-4-((7-chloro-1-methyl- 1H-indazol-4-yl)ox...)
Affinity DataIC50: >2.00E+4nMAssay Description:In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN1, NE) of human Nav1.7 (Access...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Purdue Pharma LP

US Patent
LigandPNGBDBM311152(4-((7-chloro-1-methyl-1H- indazol-4-yl)oxy)-N-(1,3...)
Affinity DataIC50: >2.00E+4nMAssay Description:In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN1, NE) of human Nav1.7 (Access...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent