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Found 5 Enz. Inhib. hit(s) with all data for assayid = 1 entry = 6219
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Arena Pharmaceuticals

US Patent
LigandPNGBDBM117016(US8664258, 32 | US9987252, 32)
Affinity DataIC50:  0.0250nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays for human 5-HT2A receptor was conducted using the 5-HT2 agonist [125]DOI as radioligand. To define nonspecific binding, 10...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Arena Pharmaceuticals

US Patent
LigandPNGBDBM117019(US8664258, 303 | US9987252, 303)
Affinity DataIC50:  0.260nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays for human 5-HT2A receptor was conducted using the 5-HT2 agonist [125]DOI as radioligand. To define nonspecific binding, 10...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Arena Pharmaceuticals

US Patent
LigandPNGBDBM117018(US8664258, 197 | US9987252, 197)
Affinity DataIC50:  1nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays for human 5-HT2A receptor was conducted using the 5-HT2 agonist [125]DOI as radioligand. To define nonspecific binding, 10...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Arena Pharmaceuticals

US Patent
LigandPNGBDBM117020(US8664258, 77)
Affinity DataIC50:  1.20nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays for human 5-HT2A receptor was conducted using the 5-HT2 agonist [125]DOI as radioligand. To define nonspecific binding, 10...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Arena Pharmaceuticals

US Patent
LigandPNGBDBM117017(US8664258, 106 | US9987252, 106)
Affinity DataIC50:  91nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays for human 5-HT2A receptor was conducted using the 5-HT2 agonist [125]DOI as radioligand. To define nonspecific binding, 10...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent