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Found 28 Enz. Inhib. hit(s) with all data for assayid = 12 entry = 50000180
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Shanghai Pharmaceuticals Holding

Curated by ChEMBL
LigandPNGBDBM50242000(CHEMBL4061378)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of c-MET (unknown origin) using TK substrate-biotin peptide as substrate preincubated for 5 to 10 mins followed by ATP addition measured a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Shanghai Pharmaceuticals Holding

Curated by ChEMBL
LigandPNGBDBM50242005(CHEMBL4104884)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of c-MET (unknown origin) using TK substrate-biotin peptide as substrate preincubated for 5 to 10 mins followed by ATP addition measured a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Shanghai Pharmaceuticals Holding

Curated by ChEMBL
LigandPNGBDBM50242021(CHEMBL4097173)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of c-MET (unknown origin) using TK substrate-biotin peptide as substrate preincubated for 5 to 10 mins followed by ATP addition measured a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Shanghai Pharmaceuticals Holding

Curated by ChEMBL
LigandPNGBDBM50146167(Capmatinib | INC-280 | INCB-28060 | NVP-INC280 | U...)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of c-MET (unknown origin) using TK substrate-biotin peptide as substrate preincubated for 5 to 10 mins followed by ATP addition measured a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Shanghai Pharmaceuticals Holding

Curated by ChEMBL
LigandPNGBDBM50242011(CHEMBL4070258)
Affinity DataIC50:  0.400nMAssay Description:Compound was evaluated for its binding affinity by displacement of [3H]- DAMPGO from opioid receptor mu by using opioid radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Shanghai Pharmaceuticals Holding

Curated by ChEMBL
LigandPNGBDBM50241992(CHEMBL4074262)
Affinity DataIC50:  0.480nMAssay Description:Inhibition of c-MET (unknown origin) using TK substrate-biotin peptide as substrate preincubated for 5 to 10 mins followed by ATP addition measured a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Shanghai Pharmaceuticals Holding

Curated by ChEMBL
LigandPNGBDBM50241992(CHEMBL4074262)
Affinity DataIC50:  0.480nMAssay Description:Compound was evaluated for its binding affinity by displacement [3H]- DSLET from Opioid receptor delta 1 by using opioid radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Shanghai Pharmaceuticals Holding

Curated by ChEMBL
LigandPNGBDBM50242007(CHEMBL4076438)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of c-MET (unknown origin) using TK substrate-biotin peptide as substrate preincubated for 5 to 10 mins followed by ATP addition measured a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Shanghai Pharmaceuticals Holding

Curated by ChEMBL
LigandPNGBDBM50241998(CHEMBL4064183)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of c-MET (unknown origin) using TK substrate-biotin peptide as substrate preincubated for 5 to 10 mins followed by ATP addition measured a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Shanghai Pharmaceuticals Holding

Curated by ChEMBL
LigandPNGBDBM50242020(CHEMBL4091023)
Affinity DataIC50:  0.5nMAssay Description:Compound was evaluated for its binding affinity by displacement of [3H]- DAMPGO from opioid receptor mu by using opioid radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Shanghai Pharmaceuticals Holding

Curated by ChEMBL
LigandPNGBDBM50242018(CHEMBL4073110)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of c-MET (unknown origin) using TK substrate-biotin peptide as substrate preincubated for 5 to 10 mins followed by ATP addition measured a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Shanghai Pharmaceuticals Holding

Curated by ChEMBL
LigandPNGBDBM50242002(CHEMBL4060354)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of c-MET (unknown origin) using TK substrate-biotin peptide as substrate preincubated for 5 to 10 mins followed by ATP addition measured a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Shanghai Pharmaceuticals Holding

Curated by ChEMBL
LigandPNGBDBM50241992(CHEMBL4074262)
Affinity DataIC50:  0.680nMAssay Description:Inhibition of c-MET (unknown origin) using TK substrate-biotin peptide as substrate preincubated for 5 to 10 mins followed by ATP addition measured a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Shanghai Pharmaceuticals Holding

Curated by ChEMBL
LigandPNGBDBM50242001(CHEMBL4083235)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of c-MET (unknown origin) using TK substrate-biotin peptide as substrate preincubated for 5 to 10 mins followed by ATP addition measured a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Shanghai Pharmaceuticals Holding

Curated by ChEMBL
LigandPNGBDBM50241999(CHEMBL4070051)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of c-MET (unknown origin) using TK substrate-biotin peptide as substrate preincubated for 5 to 10 mins followed by ATP addition measured a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Shanghai Pharmaceuticals Holding

Curated by ChEMBL
LigandPNGBDBM50242004(CHEMBL4068290)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of c-MET (unknown origin) using TK substrate-biotin peptide as substrate preincubated for 5 to 10 mins followed by ATP addition measured a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Shanghai Pharmaceuticals Holding

Curated by ChEMBL
LigandPNGBDBM50242006(CHEMBL4075149)
Affinity DataIC50:  0.900nMAssay Description:Compound was evaluated for its binding affinity by displacement of [3H]- DAMPGO from opioid receptor mu by using opioid radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Shanghai Pharmaceuticals Holding

Curated by ChEMBL
LigandPNGBDBM50242003(CHEMBL4092293)
Affinity DataIC50:  1nMAssay Description:Inhibition of c-MET (unknown origin) using TK substrate-biotin peptide as substrate preincubated for 5 to 10 mins followed by ATP addition measured a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Shanghai Pharmaceuticals Holding

Curated by ChEMBL
LigandPNGBDBM50241996(CHEMBL4093803)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of c-MET (unknown origin) using TK substrate-biotin peptide as substrate preincubated for 5 to 10 mins followed by ATP addition measured a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Shanghai Pharmaceuticals Holding

Curated by ChEMBL
LigandPNGBDBM50242012(CHEMBL4094716)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of c-MET (unknown origin) using TK substrate-biotin peptide as substrate preincubated for 5 to 10 mins followed by ATP addition measured a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Shanghai Pharmaceuticals Holding

Curated by ChEMBL
LigandPNGBDBM50242008(CHEMBL4078192)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of c-MET (unknown origin) using TK substrate-biotin peptide as substrate preincubated for 5 to 10 mins followed by ATP addition measured a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Shanghai Pharmaceuticals Holding

Curated by ChEMBL
LigandPNGBDBM50242019(CHEMBL4072776)
Affinity DataIC50:  2.60nMAssay Description:Compound was evaluated for its binding affinity by displacement [3H]- DSLET from Opioid receptor delta 1 by using opioid radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Shanghai Pharmaceuticals Holding

Curated by ChEMBL
LigandPNGBDBM50241997(CHEMBL4099662)
Affinity DataIC50:  3.5nMAssay Description:Inhibition of c-MET (unknown origin) using TK substrate-biotin peptide as substrate preincubated for 5 to 10 mins followed by ATP addition measured a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Shanghai Pharmaceuticals Holding

Curated by ChEMBL
LigandPNGBDBM50242009(CHEMBL4102466)
Affinity DataIC50:  3.80nMAssay Description:Inhibition of c-MET (unknown origin) using TK substrate-biotin peptide as substrate preincubated for 5 to 10 mins followed by ATP addition measured a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Shanghai Pharmaceuticals Holding

Curated by ChEMBL
LigandPNGBDBM50242013(CHEMBL4065641)
Affinity DataIC50:  4.30nMAssay Description:Inhibition of c-MET (unknown origin) using TK substrate-biotin peptide as substrate preincubated for 5 to 10 mins followed by ATP addition measured a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Shanghai Pharmaceuticals Holding

Curated by ChEMBL
LigandPNGBDBM50241994(CHEMBL4059611)
Affinity DataIC50:  67nMAssay Description:Inhibition of c-MET (unknown origin) using TK substrate-biotin peptide as substrate preincubated for 5 to 10 mins followed by ATP addition measured a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Shanghai Pharmaceuticals Holding

Curated by ChEMBL
LigandPNGBDBM50241993(CHEMBL4089433)
Affinity DataIC50: >100nMAssay Description:Inhibition of c-MET (unknown origin) using TK substrate-biotin peptide as substrate preincubated for 5 to 10 mins followed by ATP addition measured a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Shanghai Pharmaceuticals Holding

Curated by ChEMBL
LigandPNGBDBM50241995(CHEMBL4081567)
Affinity DataIC50: >100nMAssay Description:Inhibition of c-MET (unknown origin) using TK substrate-biotin peptide as substrate preincubated for 5 to 10 mins followed by ATP addition measured a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed