BindingDB PrimarySearch

Found 1 Enz. Inhib. hit(s) with all data for assayid = 12 entry = 50000261

Non-receptor tyrosine-protein kinase TYK2/Tyrosine-protein kinase JAK2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

BDBM159748(US10966980, Example 2 | US9035074, 2)

IC50: >1.65E+4nMAssay Description:Inhibition of JAK2/TYK2 in human whole blood assessed as reduction in IL-23 induced STAT3 phosphorylation preincubated for 45 mins followed by IL-23 ...More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
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Details Article PubMed PDB

3D Structure (crystal)