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Found 11 Enz. Inhib. hit(s) with all data for assayid = 2 entry = 2759
TargetDNA gyrase subunit B(Escherichia coli (strain K12))
The Florida International University Board of Trustees

US Patent
LigandPNGBDBM50259245(CHEMBL4064127 | US10266550, Compound 17a)
Affinity DataIC50:  3.90E+3nMAssay Description:DNA gyrase supercoiling assays were carried out by mixing the compounds and the enzyme in a similar manner as above (EcTopI relaxation inhibition ass...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDNA gyrase subunit B(Escherichia coli (strain K12))
The Florida International University Board of Trustees

US Patent
LigandPNGBDBM50259244(CHEMBL4076393 | US10266550, Compound 16)
Affinity DataIC50:  3.90E+3nMAssay Description:DNA gyrase supercoiling assays were carried out by mixing the compounds and the enzyme in a similar manner as above (EcTopI relaxation inhibition ass...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDNA gyrase subunit B(Escherichia coli (strain K12))
The Florida International University Board of Trustees

US Patent
LigandPNGBDBM50259248(CHEMBL4104625 | US10266550, Compound 17bbSelectivi...)
Affinity DataIC50:  3.90E+3nMAssay Description:DNA gyrase supercoiling assays were carried out by mixing the compounds and the enzyme in a similar manner as above (EcTopI relaxation inhibition ass...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDNA gyrase subunit B(Escherichia coli (strain K12))
The Florida International University Board of Trustees

US Patent
LigandPNGBDBM50259221(CHEMBL4097472 | US10266550, Compound 11d)
Affinity DataIC50:  7.80E+3nMAssay Description:DNA gyrase supercoiling assays were carried out by mixing the compounds and the enzyme in a similar manner as above (EcTopI relaxation inhibition ass...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDNA gyrase subunit B(Escherichia coli (strain K12))
The Florida International University Board of Trustees

US Patent
LigandPNGBDBM50259215(CHEMBL4064887 | US10266550, Compound 11b)
Affinity DataIC50:  1.17E+4nMAssay Description:DNA gyrase supercoiling assays were carried out by mixing the compounds and the enzyme in a similar manner as above (EcTopI relaxation inhibition ass...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDNA gyrase subunit B(Escherichia coli (strain K12))
The Florida International University Board of Trustees

US Patent
LigandPNGBDBM50259247(CHEMBL4065223 | US10266550, Compound 11g)
Affinity DataIC50:  1.56E+4nMAssay Description:DNA gyrase supercoiling assays were carried out by mixing the compounds and the enzyme in a similar manner as above (EcTopI relaxation inhibition ass...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDNA gyrase subunit B(Escherichia coli (strain K12))
The Florida International University Board of Trustees

US Patent
LigandPNGBDBM50259242(CHEMBL4072011 | US10266550, Compound 11e)
Affinity DataIC50:  2.34E+4nMAssay Description:DNA gyrase supercoiling assays were carried out by mixing the compounds and the enzyme in a similar manner as above (EcTopI relaxation inhibition ass...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDNA gyrase subunit B(Escherichia coli (strain K12))
The Florida International University Board of Trustees

US Patent
LigandPNGBDBM50259214(CHEMBL4061346 | US10266550, Compound 11a)
Affinity DataIC50:  2.34E+4nMAssay Description:DNA gyrase supercoiling assays were carried out by mixing the compounds and the enzyme in a similar manner as above (EcTopI relaxation inhibition ass...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDNA gyrase subunit B(Escherichia coli (strain K12))
The Florida International University Board of Trustees

US Patent
LigandPNGBDBM50259213(CHEMBL4079855 | US10266550, Compound 7e)
Affinity DataIC50:  6.25E+4nMAssay Description:DNA gyrase supercoiling assays were carried out by mixing the compounds and the enzyme in a similar manner as above (EcTopI relaxation inhibition ass...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDNA gyrase subunit B(Escherichia coli (strain K12))
The Florida International University Board of Trustees

US Patent
LigandPNGBDBM50259246(CHEMBL4066307 | US10266550, Compound 10a)
Affinity DataIC50:  9.38E+4nMAssay Description:DNA gyrase supercoiling assays were carried out by mixing the compounds and the enzyme in a similar manner as above (EcTopI relaxation inhibition ass...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDNA gyrase subunit B(Escherichia coli (strain K12))
The Florida International University Board of Trustees

US Patent
LigandPNGBDBM50259212(CHEMBL2002459 | US10266550, Compound 1)
Affinity DataIC50: >1.25E+5nMAssay Description:DNA gyrase supercoiling assays were carried out by mixing the compounds and the enzyme in a similar manner as above (EcTopI relaxation inhibition ass...More data for this Ligand-Target Pair
In DepthDetails US Patent