Compile Data Set for Download or QSAR
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Found 4 Enz. Inhib. hit(s) with all data for assayid = 20 entry = 50009527
TargetJAK3/JAK1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50193995(3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyr...)
Affinity DataIC50:  51nMAssay Description:Inhibition of JAK1/JAK3 signaling pathway in human lymphocytes of whole blood assessed as reduction in IL-21 induced STAT3 phosphorylation preincubat...More data for this Ligand-Target Pair
TargetJAK3/JAK1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50193995(3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyr...)
Affinity DataIC50:  51nMAssay Description:Inhibition of JAK1/JAK3 signaling pathway in human lymphocytes of whole blood assessed as reduction in IL-21 induced STAT3 phosphorylation preincubat...More data for this Ligand-Target Pair
TargetJAK3/JAK1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM329924(US10463675, Example 7 | US10980815, Ex. No. 7 | US...)
Affinity DataIC50:  204nMAssay Description:Inhibition of JAK1/JAK3 signaling pathway in human lymphocytes of whole blood assessed as reduction in IL-21 induced STAT3 phosphorylation preincubat...More data for this Ligand-Target Pair
TargetJAK3/JAK1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM329924(US10463675, Example 7 | US10980815, Ex. No. 7 | US...)
Affinity DataIC50:  204nMAssay Description:Inhibition of JAK1/JAK3 signaling pathway in human lymphocytes of whole blood assessed as reduction in IL-21 induced STAT3 phosphorylation preincubat...More data for this Ligand-Target Pair