Affinity DataKi: 1.70nM ΔG°: -49.6kJ/molepH: 7.2 T: 2°CAssay Description:To determine inhibition constants (Ki), compounds were diluted serially in DMSO and added to 50 uL kinase reactions containing 5 nM purified JAK3 enz...More data for this Ligand-Target Pair
Affinity DataKi: 2.90nM ΔG°: -48.2kJ/molepH: 7.2 T: 2°CAssay Description:To determine inhibition constants (Ki), compounds were diluted serially in DMSO and added to 50 uL kinase reactions containing 5 nM purified JAK3 enz...More data for this Ligand-Target Pair
Affinity DataKi: 12.4nM ΔG°: -44.7kJ/molepH: 7.2 T: 2°CAssay Description:To determine inhibition constants (Ki), compounds were diluted serially in DMSO and added to 50 uL kinase reactions containing 5 nM purified JAK3 enz...More data for this Ligand-Target Pair
Affinity DataKi: 14.5nM ΔG°: -44.3kJ/molepH: 7.2 T: 2°CAssay Description:To determine inhibition constants (Ki), compounds were diluted serially in DMSO and added to 50 uL kinase reactions containing 5 nM purified JAK3 enz...More data for this Ligand-Target Pair
Affinity DataKi: 15.7nM ΔG°: -44.1kJ/molepH: 7.2 T: 2°CAssay Description:To determine inhibition constants (Ki), compounds were diluted serially in DMSO and added to 50 uL kinase reactions containing 5 nM purified JAK3 enz...More data for this Ligand-Target Pair
Affinity DataKi: 25.4nM ΔG°: -42.9kJ/molepH: 7.2 T: 2°CAssay Description:To determine inhibition constants (Ki), compounds were diluted serially in DMSO and added to 50 uL kinase reactions containing 5 nM purified JAK3 enz...More data for this Ligand-Target Pair
Affinity DataKi: 28.6nM ΔG°: -42.6kJ/molepH: 7.2 T: 2°CAssay Description:To determine inhibition constants (Ki), compounds were diluted serially in DMSO and added to 50 uL kinase reactions containing 5 nM purified JAK3 enz...More data for this Ligand-Target Pair
Affinity DataKi: 39.7nM ΔG°: -41.8kJ/molepH: 7.2 T: 2°CAssay Description:To determine inhibition constants (Ki), compounds were diluted serially in DMSO and added to 50 uL kinase reactions containing 5 nM purified JAK3 enz...More data for this Ligand-Target Pair
Affinity DataKi: 55.6nM ΔG°: -41.0kJ/molepH: 7.2 T: 2°CAssay Description:To determine inhibition constants (Ki), compounds were diluted serially in DMSO and added to 50 uL kinase reactions containing 5 nM purified JAK3 enz...More data for this Ligand-Target Pair
Affinity DataKi: 95.1nM ΔG°: -39.7kJ/molepH: 7.2 T: 2°CAssay Description:To determine inhibition constants (Ki), compounds were diluted serially in DMSO and added to 50 uL kinase reactions containing 5 nM purified JAK3 enz...More data for this Ligand-Target Pair