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Found 7 Enz. Inhib. hit(s) with all data for assayid = 4 entry = 1383
TargetKetohexokinase(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM319582(US10174007, Example 1 | US10787438, Example 1 | US...)
Affinity DataIC50:  7.30nMAssay Description:A fourth assay, referred to as Assay D, was performed using human KHK-A to assess the potency of compounds in inhibiting activity of this enzyme. Com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKetohexokinase(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM319602(US10174007, Example 42 | US10787438, Example 42 | ...)
Affinity DataIC50:  10.5nMAssay Description:A fourth assay, referred to as Assay D, was performed using human KHK-A to assess the potency of compounds in inhibiting activity of this enzyme. Com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKetohexokinase(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM319600(US10174007, Example 24 | US10787438, Example 24 | ...)
Affinity DataIC50:  12.1nMAssay Description:A fourth assay, referred to as Assay D, was performed using human KHK-A to assess the potency of compounds in inhibiting activity of this enzyme. Com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKetohexokinase(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM319601(US10174007, Example 40 | US10787438, Example 40 | ...)
Affinity DataIC50:  37.9nMAssay Description:A fourth assay, referred to as Assay D, was performed using human KHK-A to assess the potency of compounds in inhibiting activity of this enzyme. Com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKetohexokinase(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM319603(US10174007, Example 43 | US10787438, Example 43 | ...)
Affinity DataIC50:  48.6nMAssay Description:A fourth assay, referred to as Assay D, was performed using human KHK-A to assess the potency of compounds in inhibiting activity of this enzyme. Com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKetohexokinase(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM319585(US10174007, Example 4 | US10787438, Example 4 | US...)
Affinity DataIC50:  66nMAssay Description:A fourth assay, referred to as Assay D, was performed using human KHK-A to assess the potency of compounds in inhibiting activity of this enzyme. Com...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetKetohexokinase(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM319586(US10174007, Example 5 | US10787438, Example 5 | US...)
Affinity DataIC50:  95.5nMAssay Description:A fourth assay, referred to as Assay D, was performed using human KHK-A to assess the potency of compounds in inhibiting activity of this enzyme. Com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent