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Found 17 Enz. Inhib. hit(s) with all data for assayid = 5 entry = 50000470
TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50006185(5-{2-[1-Benzyl-2-(4-methoxymethoxy-piperidin-1-yl)...)
Affinity DataIC50:  1nMpH: 6.0Assay Description:In vitro potency against human plasma renin at a pH of 7.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50006152(2-[1-Benzyl-2-(4-methoxymethoxy-piperidin-1-yl)-2-...)
Affinity DataIC50:  1nMpH: 6.0Assay Description:In vitro potency against human plasma renin at a pH of 7.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50006204(5-{2-[1-Benzyl-2-(4-methoxymethoxy-piperidin-1-yl)...)
Affinity DataIC50:  1.30nMpH: 6.0Assay Description:In vitro potency against human plasma renin at a pH of 7.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50006176(CHEMBL264194 | {4-[2-(2-tert-Butoxycarbonylamino-3...)
Affinity DataIC50:  1.30nMpH: 6.0Assay Description:In vitro activity against human renin (pH 6.0)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50006208(5-{2-[1-Benzyl-2-(4-methoxymethoxy-piperidin-1-yl)...)
Affinity DataIC50:  1.30nMpH: 6.0Assay Description:In vitro potency against human plasma renin at a pH of 7.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50006197(5-{2-[1-Benzyl-2-(4-methoxymethoxy-piperidin-1-yl)...)
Affinity DataIC50:  1.40nMpH: 6.0Assay Description:In vitro potency against human plasma renin at a pH of 7.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50006196((4-{2-[1-Benzyl-2-(4-methoxymethoxy-piperidin-1-yl...)
Affinity DataIC50:  1.5nMpH: 6.0Assay Description:In vitro potency against human plasma renin at a pH of 7.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50006207(CHEMBL301395 | {4-[2-(2-tert-Butoxycarbonylamino-3...)
Affinity DataIC50:  1.70nMpH: 6.0Assay Description:In vitro potency against human plasma renin at a pH of 7.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50006200((4-{2-[1-Benzyl-2-(4-methoxymethoxy-piperidin-1-yl...)
Affinity DataIC50:  1.80nMpH: 6.0Assay Description:In vitro potency against human plasma renin at a pH of 7.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50006213(CHEMBL48343 | {4-[2-(2-tert-Butoxycarbonylamino-3-...)
Affinity DataIC50:  2.30nMpH: 6.0Assay Description:In vitro activity against human renin (pH 6.0)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50006177(2-[1-Benzyl-2-(4-methoxymethoxy-piperidin-1-yl)-2-...)
Affinity DataIC50:  2.40nMpH: 6.0Assay Description:In vitro activity against human renin (pH 6.0)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50006187((2S,4S,5S)-5-{(S)-2-[(S)-1-Benzyl-2-(4-methoxymeth...)
Affinity DataIC50:  2.40nMpH: 6.0Assay Description:In vitro potency against human plasma renin at a pH of 7.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50006186(5-{2-[1-Benzyl-2-(4-methoxymethoxy-piperidin-1-yl)...)
Affinity DataIC50:  2.5nMpH: 6.0Assay Description:In vitro activity against human renin (pH 6.0)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50006210(2-[1-Benzyl-2-(4-methoxymethoxy-piperidin-1-yl)-2-...)
Affinity DataIC50:  3.20nMpH: 6.0Assay Description:In vitro activity against human renin (pH 6.0)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50006212((4-{2-[1-Benzyl-2-(4-methoxymethoxy-piperidin-1-yl...)
Affinity DataIC50:  5nMpH: 6.0Assay Description:In vitro potency against human plasma renin at a pH of 7.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50006194(CHEMBL48481 | {1-[1-(1-Cyclohexylmethyl-2-hydroxy-...)
Affinity DataIC50:  6nMpH: 6.0Assay Description:In vitro potency against human plasma renin at a pH of 7.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50006193(5-{2-[1-Benzyl-2-(4-methoxymethoxy-piperidin-1-yl)...)
Affinity DataIC50:  57nMpH: 6.0Assay Description:In vitro potency against human plasma renin at a pH of 7.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed