Compile Data Set for Download or QSAR
maximum 50k data
Found 15 Enz. Inhib. hit(s) with all data for assayid = 5 entry = 50046174
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Kansas Specialized Chemistry Center

Curated by ChEMBL
LigandPNGBDBM82551(C18130 | CAS_105618-26-6 | NOR-BNI (HCI)2 | NORBNI)
Affinity DataIC50:  4.60nMAssay Description:Antagonist activity against HA-tagged human recombinant kappa opioid receptor expressed in CHO cells assessed as inhibition of U69,593-induced ERK ph...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Kansas Specialized Chemistry Center

Curated by ChEMBL
LigandPNGBDBM50097699(CHEMBL3590195)
Affinity DataIC50:  49nMAssay Description:Antagonist activity against HA-tagged human recombinant kappa opioid receptor expressed in CHO cells assessed as inhibition of U69,593-induced ERK ph...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Kansas Specialized Chemistry Center

Curated by ChEMBL
LigandPNGBDBM50097701(CHEMBL3590197)
Affinity DataIC50:  76nMAssay Description:Antagonist activity against HA-tagged human recombinant kappa opioid receptor expressed in CHO cells assessed as inhibition of U69,593-induced ERK ph...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Kansas Specialized Chemistry Center

Curated by ChEMBL
LigandPNGBDBM50097704(CHEMBL3590200)
Affinity DataIC50:  87nMAssay Description:Antagonist activity against HA-tagged human recombinant kappa opioid receptor expressed in CHO cells assessed as inhibition of U69,593-induced ERK ph...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Kansas Specialized Chemistry Center

Curated by ChEMBL
LigandPNGBDBM50097703(CHEMBL3590199)
Affinity DataIC50:  107nMAssay Description:Antagonist activity against HA-tagged human recombinant kappa opioid receptor expressed in CHO cells assessed as inhibition of U69,593-induced ERK ph...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Kansas Specialized Chemistry Center

Curated by ChEMBL
LigandPNGBDBM50097700(CHEMBL3590196)
Affinity DataIC50:  143nMAssay Description:Antagonist activity against HA-tagged human recombinant kappa opioid receptor expressed in CHO cells assessed as inhibition of U69,593-induced ERK ph...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Kansas Specialized Chemistry Center

Curated by ChEMBL
LigandPNGBDBM50097697(CHEMBL3590193)
Affinity DataIC50:  258nMAssay Description:Antagonist activity against HA-tagged human recombinant kappa opioid receptor expressed in CHO cells assessed as inhibition of U69,593-induced ERK ph...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Kansas Specialized Chemistry Center

Curated by ChEMBL
LigandPNGBDBM50097698(CHEMBL3590194)
Affinity DataIC50:  314nMAssay Description:Antagonist activity against HA-tagged human recombinant kappa opioid receptor expressed in CHO cells assessed as inhibition of U69,593-induced ERK ph...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Kansas Specialized Chemistry Center

Curated by ChEMBL
LigandPNGBDBM50097696(CHEMBL3590192)
Affinity DataIC50:  400nMAssay Description:Antagonist activity against HA-tagged human recombinant kappa opioid receptor expressed in CHO cells assessed as inhibition of U69,593-induced ERK ph...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Kansas Specialized Chemistry Center

Curated by ChEMBL
LigandPNGBDBM50097695(CHEMBL3590191)
Affinity DataIC50:  406nMAssay Description:Antagonist activity against HA-tagged human recombinant kappa opioid receptor expressed in CHO cells assessed as inhibition of U69,593-induced ERK ph...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Kansas Specialized Chemistry Center

Curated by ChEMBL
LigandPNGBDBM54817(4-[[(4-methylphenyl)sulfonylamino]methyl]-N-[2-[(p...)
Affinity DataIC50:  591nMAssay Description:Antagonist activity against HA-tagged human recombinant kappa opioid receptor expressed in CHO cells assessed as inhibition of U69,593-induced ERK ph...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Kansas Specialized Chemistry Center

Curated by ChEMBL
LigandPNGBDBM71581(KSC-5-280C | KUC104162N | N-[2-[(4-bromobenzyl)-is...)
Affinity DataIC50:  750nMAssay Description:Antagonist activity against HA-tagged human recombinant kappa opioid receptor expressed in CHO cells assessed as inhibition of U69,593-induced ERK ph...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Kansas Specialized Chemistry Center

Curated by ChEMBL
LigandPNGBDBM50097694(CHEMBL3590190)
Affinity DataIC50:  1.12E+3nMAssay Description:Antagonist activity against HA-tagged human recombinant kappa opioid receptor expressed in CHO cells assessed as inhibition of U69,593-induced ERK ph...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Kansas Specialized Chemistry Center

Curated by ChEMBL
LigandPNGBDBM50097702(CHEMBL3590198)
Affinity DataIC50:  1.20E+3nMAssay Description:Antagonist activity against HA-tagged human recombinant kappa opioid receptor expressed in CHO cells assessed as inhibition of U69,593-induced ERK ph...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Kansas Specialized Chemistry Center

Curated by ChEMBL
LigandPNGBDBM50097705(CHEMBL3590201)
Affinity DataIC50:  1.34E+3nMAssay Description:Antagonist activity against HA-tagged human recombinant kappa opioid receptor expressed in CHO cells assessed as inhibition of U69,593-induced ERK ph...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed