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Found 6 Enz. Inhib. hit(s) with all data for assayid = 6 entry = 50013847
TargetVasopressin V1a receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50135414(Biphenyl-2-carboxylic acid {4-[2-(2-hydroxy-ethyl)...)
Affinity DataIC50:  150nMAssay Description:Ability to displace [3H]-arginine vasopressin in cloned human V2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50135413((5-{4-[(Biphenyl-2-carbonyl)-amino]-benzoyl}-2,3,4...)
Affinity DataIC50:  740nMAssay Description:Ability to displace [3H]-arginine vasopressin in cloned human V2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50135420(((S)-5-{4-[(Biphenyl-2-carbonyl)-amino]-benzoyl}-2...)
Affinity DataIC50:  1.76E+3nMAssay Description:Inhibition of vasopressin induced calcium immobilization in human V1a receptor expressing cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50135418(3-((S)-5-{4-[(Biphenyl-2-carbonyl)-amino]-benzoyl}...)
Affinity DataIC50:  2.01E+3nMAssay Description:Inhibition of vasopressin induced calcium immobilization in human V1a receptor expressing cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50135417(((R)-5-{4-[(Biphenyl-2-carbonyl)-amino]-benzoyl}-2...)
Affinity DataIC50:  2.13E+3nMAssay Description:Inhibition of vasopressin induced calcium immobilization in human V1a receptor expressing cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50135415(3-((R)-5-{4-[(Biphenyl-2-carbonyl)-amino]-benzoyl}...)
Affinity DataIC50:  4.63E+3nMAssay Description:Inhibition of vasopressin induced cAMP accumulation in human V2 receptor expressing cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed