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Found 20 Enz. Inhib. hit(s) with all data for assayid = 7 entry = 50006811
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Université

Curated by ChEMBL
LigandPNGBDBM82368(CAS_121851 | CHEMBL11592 | CHEMBL301060 | NSC_1218...)
Affinity DataIC50:  0.300nMAssay Description:Binding affinity to 5-hydroxytryptamine 1A receptor in rat hippocampus membranes,3H-8-OH-DPAT and buspirone for nonspecific binding (NSB)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Université

Curated by ChEMBL
LigandPNGBDBM82368(CAS_121851 | CHEMBL11592 | CHEMBL301060 | NSC_1218...)
Affinity DataIC50:  0.300nMAssay Description:Binding affinity to 5-hydroxytryptamine 1A receptor in rat hippocampus membranes,3H-8-OH-DPAT and buspirone for nonspecific binding (NSB)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Université

Curated by ChEMBL
LigandPNGBDBM21393(7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-o...)
Affinity DataIC50:  2.40nMAssay Description:Binding affinity to 5-hydroxytryptamine 1A receptor in rat hippocampus membranes,3H-8-OH-DPAT and buspirone for nonspecific binding (NSB)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Université

Curated by ChEMBL
LigandPNGBDBM50054143((+) 8-{4-[5-methoxyspiro[3,4-dihydro-2H-chromene-3...)
Affinity DataIC50:  6.72nMAssay Description:Binding affinity to 5-hydroxytryptamine 1A receptor in rat hippocampus membranes,3H-8-OH-DPAT and buspirone for nonspecific binding (NSB)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Université

Curated by ChEMBL
LigandPNGBDBM50054147(8-{4-[5-methoxyspiro[3,4-dihydro-2H-chromene-3,2'-...)
Affinity DataIC50:  8.81nMAssay Description:Binding affinity to 5-hydroxytryptamine 1A receptor in rat hippocampus membranes,3H-8-OH-DPAT and buspirone for nonspecific binding (NSB)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Université

Curated by ChEMBL
LigandPNGBDBM50054143((+) 8-{4-[5-methoxyspiro[3,4-dihydro-2H-chromene-3...)
Affinity DataIC50:  10.6nMAssay Description:Binding affinity to 5-hydroxytryptamine 1A receptor in rat hippocampus membranes,3H-8-OH-DPAT and buspirone for nonspecific binding (NSB)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Université

Curated by ChEMBL
LigandPNGBDBM50036862((5-Methoxy-chroman-3-yl)-dipropyl-amine | CHEMBL28...)
Affinity DataIC50:  20nMAssay Description:Binding affinity to 5-hydroxytryptamine 1A receptor in rat hippocampus membranes,3H-8-OH-DPAT and buspirone for nonspecific binding (NSB)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Université

Curated by ChEMBL
LigandPNGBDBM50005127(1,1-Dioxo-2-[4-(4-pyrimidin-2-yl-piperazin-1-yl)-b...)
Affinity DataIC50:  35nMAssay Description:Binding affinity to 5-hydroxytryptamine 1A receptor in rat hippocampus membranes,3H-8-OH-DPAT and buspirone for nonspecific binding (NSB)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Université

Curated by ChEMBL
LigandPNGBDBM50001859((buspirone) 8-[4-(4-Pyrimidin-2-yl-piperazin-1-yl)...)
Affinity DataIC50:  60nMAssay Description:Binding affinity to 5-hydroxytryptamine 1A receptor in rat hippocampus membranes,3H-8-OH-DPAT and buspirone for nonspecific binding (NSB)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Université

Curated by ChEMBL
LigandPNGBDBM50054149(1'-[4-(4-fluorophenylcarboxamido)butyl]-5-methoxys...)
Affinity DataIC50:  62.8nMAssay Description:Binding affinity to 5-hydroxytryptamine 1A receptor in rat hippocampus membranes,3H-8-OH-DPAT and buspirone for nonspecific binding (NSB)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Université

Curated by ChEMBL
LigandPNGBDBM50054142(5-methoxy-1'-[4-(4-methylphenylsulfonamido)butyl]s...)
Affinity DataIC50:  68nMAssay Description:Binding affinity to 5-hydroxytryptamine 1A receptor in rat hippocampus membranes,3H-8-OH-DPAT and buspirone for nonspecific binding (NSB)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Université

Curated by ChEMBL
LigandPNGBDBM50054145(5-methoxy-1'-propylspiro[3,4-dihydro-2H-chromene-3...)
Affinity DataIC50:  74.6nMAssay Description:Binding affinity to 5-hydroxytryptamine 1A receptor in rat hippocampus membranes,3H-8-OH-DPAT and buspirone for nonspecific binding (NSB)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Université

Curated by ChEMBL
LigandPNGBDBM50054155(8-{4-[1'-propylspiro[3,4-dihydro-2H-chromene-3,2'-...)
Affinity DataIC50:  101nMAssay Description:Binding affinity to 5-hydroxytryptamine 1A receptor in rat hippocampus membranes,3H-8-OH-DPAT and buspirone for nonspecific binding (NSB)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Université

Curated by ChEMBL
LigandPNGBDBM50054154(8-[4-spiro[3,4-dihydro-2H-chromene-3,2'-(tetrahydr...)
Affinity DataIC50:  178nMAssay Description:Binding affinity to 5-hydroxytryptamine 1A receptor in rat hippocampus membranes,3H-8-OH-DPAT and buspirone for nonspecific binding (NSB)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Université

Curated by ChEMBL
LigandPNGBDBM50054152(5-methoxyspiro[3,4-dihydro-2H-chromene-3,2'-(tetra...)
Affinity DataIC50:  298nMAssay Description:Binding affinity to 5-hydroxytryptamine 1A receptor in rat hippocampus membranes,3H-8-OH-DPAT and buspirone for nonspecific binding (NSB)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Université

Curated by ChEMBL
LigandPNGBDBM50054150(5-methoxy-1'-propylspiro[3,4-dihydro-2H-chromene-3...)
Affinity DataIC50:  420nMAssay Description:Binding affinity to 5-hydroxytryptamine 1A receptor in rat hippocampus membranes,3H-8-OH-DPAT and buspirone for nonspecific binding (NSB)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Université

Curated by ChEMBL
LigandPNGBDBM50054144(1'-propylspiro[3,4-dihydro-2H-chromene-3,2'-(tetra...)
Affinity DataIC50:  1.30E+3nMAssay Description:Binding affinity to 5-hydroxytryptamine 1A receptor in rat hippocampus membranes,3H-8-OH-DPAT and buspirone for nonspecific binding (NSB)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Université

Curated by ChEMBL
LigandPNGBDBM50054148(5-methoxyspiro[3,4-dihydro-2H-chromene-3,2'-(tetra...)
Affinity DataIC50:  4.37E+3nMAssay Description:Binding affinity to 5-hydroxytryptamine 1A receptor in rat hippocampus membranes,3H-8-OH-DPAT and buspirone for nonspecific binding (NSB)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Université

Curated by ChEMBL
LigandPNGBDBM50054151(5-methoxy-1'-propylspiro[3,4-dihydro-2H-chromene-3...)
Affinity DataIC50:  1.42E+4nMAssay Description:Binding affinity to 5-hydroxytryptamine 1A receptor in rat hippocampus membranes,3H-8-OH-DPAT and buspirone for nonspecific binding (NSB)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Université

Curated by ChEMBL
LigandPNGBDBM50054153(1-[5-methoxyspiro[3,4-dihydro-2H-chromene-3,2'-(te...)
Affinity DataIC50:  8.14E+4nMAssay Description:Binding affinity to 5-hydroxytryptamine 1A receptor in rat hippocampus membranes,3H-8-OH-DPAT and buspirone for nonspecific binding (NSB)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed