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Found 4 Enz. Inhib. hit(s) with all data for assayid = 8 entry = 10228
TargetRous sarcoma virus integrase(Rous sarcoma virus (strain Prague C) (RSV-PrC))
Janssen Biopharma

US Patent
LigandPNGBDBM521555(((2S,3S,4R,5R)-5-(4-Aminopyrrolo[2,1-f][1,2,4]tria...)
Affinity DataIC50:  30nMAssay Description:Standard RSV polymerase assays were conducted in the presence of 3 μL extract of RSV-infected cells in a reaction buffer containing 50 mM tris-a...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetRous sarcoma virus integrase(Rous sarcoma virus (strain Prague C) (RSV-PrC))
Janssen Biopharma

US Patent
LigandPNGBDBM521557(((2R,3S,4R,5R)-5-(4-Aminopyrrolo[2,1-f][1,2,4]tria...)
Affinity DataIC50:  30nMAssay Description:Standard RSV polymerase assays were conducted in the presence of 3 μL extract of RSV-infected cells in a reaction buffer containing 50 mM tris-a...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetRous sarcoma virus integrase(Rous sarcoma virus (strain Prague C) (RSV-PrC))
Janssen Biopharma

US Patent
LigandPNGBDBM50236025(CHEMBL2016761 | US11149049, No. C2)
Affinity DataIC50:  120nMAssay Description:Standard RSV polymerase assays were conducted in the presence of 3 μL extract of RSV-infected cells in a reaction buffer containing 50 mM tris-a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRous sarcoma virus integrase(Rous sarcoma virus (strain Prague C) (RSV-PrC))
Janssen Biopharma

US Patent
LigandPNGBDBM521556(((2R,3S,4R,5R)-5-(4-Aminopyrrolo[2,1-f][1,2,4]tria...)
Affinity DataIC50: >1.00E+4nMAssay Description:Standard RSV polymerase assays were conducted in the presence of 3 μL extract of RSV-infected cells in a reaction buffer containing 50 mM tris-a...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent