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Found 5 of ph data with Target = 'ATP-dependent translocase ABCB1'
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Neurovive Pharmaceutical

US Patent
LigandPNGBDBM172715(US9090657, DEBIO-025, 2)
Affinity DataIC50:  720nMpH: 7.4 T: 2°CAssay Description:To assess the inhibition of the P-glycoprotein (Pgp/MDR1) transporter, an in vitro ATPase assay from Cyprotex was used. MDR1MDCK cells obtained from ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Neurovive Pharmaceutical

US Patent
LigandPNGBDBM172718(US11802108, Compound CSA | US9090657, Cyclosporine...)
Affinity DataIC50:  730nMpH: 7.4 T: 2°CAssay Description:To assess the inhibition of the P-glycoprotein (Pgp/MDR1) transporter, an in vitro ATPase assay from Cyprotex was used. MDR1MDCK cells obtained from ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Neurovive Pharmaceutical

US Patent
LigandPNGBDBM106203(US9695174, I-1)
Affinity DataIC50: >3.00E+4nMpH: 7.4 T: 2°CAssay Description:To determine potency of compounds on inhibition of transporters, bi-directional transport studies are performed in Caco-2 cells (American Type Cultur...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Neurovive Pharmaceutical

US Patent
LigandPNGBDBM50305083(3-((3S,6S)-6-Isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,...)
Affinity DataIC50: >3.00E+4nMpH: 7.4 T: 2°CAssay Description:To determine potency of compounds on inhibition of transporters, bi-directional transport studies are performed in Caco-2 cells (American Type Cultur...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Neurovive Pharmaceutical

US Patent
LigandPNGBDBM172717(US9090657, 24)
Affinity DataIC50: >5.00E+4nMpH: 7.4 T: 2°CAssay Description:To assess the inhibition of the P-glycoprotein (Pgp/MDR1) transporter, an in vitro ATPase assay from Cyprotex was used. MDR1MDCK cells obtained from ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent