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Found 28 of ph data with Target = 'Broad substrate specificity ATP-binding cassette transporter ABCG2'
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Millennium Pharmaceuticals

US Patent
LigandPNGBDBM106203(US9695174, I-1)
Affinity DataIC50:  600nMpH: 7.4 T: 2°CAssay Description:To determine potency of compounds on inhibition of transporters, bi-directional transport studies are performed in Caco-2 cells (American Type Cultur...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Millennium Pharmaceuticals

US Patent
LigandPNGBDBM32628(FTC | Fumitremorgin C)
Affinity DataIC50:  790nMpH: 7.4 T: 2°CAssay Description:IC50 and maximal activities for inhibition of PhA accumulation were determined from dose-response curves. The accumulation of PhA, a fluorescent ABCG...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Millennium Pharmaceuticals

US Patent
LigandPNGBDBM106207(US9695174, 12)
Affinity DataIC50:  1.98E+3nMpH: 7.4 T: 2°CAssay Description:To determine potency of compounds on inhibition of transporters, bi-directional transport studies are performed in Caco-2 cells (American Type Cultur...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Millennium Pharmaceuticals

US Patent
LigandPNGBDBM32630(NSC19139)
Affinity DataIC50:  2.60E+3nMpH: 7.4 T: 2°CAssay Description:IC50 and maximal activities for inhibition of PhA accumulation were determined from dose-response curves. The accumulation of PhA, a fluorescent ABCG...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Millennium Pharmaceuticals

US Patent
LigandPNGBDBM106221(US9695174, Ko134)
Affinity DataIC50:  3.25E+3nMpH: 7.4 T: 2°CAssay Description:To determine potency of compounds on inhibition of transporters, bi-directional transport studies are performed in Caco-2 cells (American Type Cultur...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Millennium Pharmaceuticals

US Patent
LigandPNGBDBM32637(NSC375985)
Affinity DataIC50:  3.70E+3nMpH: 7.4 T: 2°CAssay Description:IC50 and maximal activities for inhibition of PhA accumulation were determined from dose-response curves. The accumulation of PhA, a fluorescent ABCG...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Millennium Pharmaceuticals

US Patent
LigandPNGBDBM32633(NSC168201)
Affinity DataIC50:  3.90E+3nMpH: 7.4 T: 2°CAssay Description:IC50 and maximal activities for inhibition of PhA accumulation were determined from dose-response curves. The accumulation of PhA, a fluorescent ABCG...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Millennium Pharmaceuticals

US Patent
LigandPNGBDBM32632(NSC120688)
Affinity DataIC50:  4.30E+3nMpH: 7.4 T: 2°CAssay Description:IC50 and maximal activities for inhibition of PhA accumulation were determined from dose-response curves. The accumulation of PhA, a fluorescent ABCG...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Millennium Pharmaceuticals

US Patent
LigandPNGBDBM32629(NSC11668 | cid_223753)
Affinity DataIC50:  4.50E+3nMpH: 7.4 T: 2°CAssay Description:IC50 and maximal activities for inhibition of PhA accumulation were determined from dose-response curves. The accumulation of PhA, a fluorescent ABCG...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Millennium Pharmaceuticals

US Patent
LigandPNGBDBM32636(NSC320852)
Affinity DataIC50:  4.60E+3nMpH: 7.4 T: 2°CAssay Description:IC50 and maximal activities for inhibition of PhA accumulation were determined from dose-response curves. The accumulation of PhA, a fluorescent ABCG...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Millennium Pharmaceuticals

US Patent
LigandPNGBDBM32635(NSC306698)
Affinity DataIC50:  5.40E+3nMpH: 7.4 T: 2°CAssay Description:IC50 and maximal activities for inhibition of PhA accumulation were determined from dose-response curves. The accumulation of PhA, a fluorescent ABCG...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Millennium Pharmaceuticals

US Patent
LigandPNGBDBM32634(NSC303769)
Affinity DataIC50:  5.80E+3nMpH: 7.4 T: 2°CAssay Description:IC50 and maximal activities for inhibition of PhA accumulation were determined from dose-response curves. The accumulation of PhA, a fluorescent ABCG...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Millennium Pharmaceuticals

US Patent
LigandPNGBDBM32624(Botryllamide G, 7 | US8470888, Botryllamide G)
Affinity DataIC50:  6.90E+3nMpH: 7.4 T: 2°CAssay Description:IC50 and maximal activities for inhibition of PhA accumulation were determined from dose-response curves. The accumulation of PhA, a fluorescent ABCG...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Millennium Pharmaceuticals

US Patent
LigandPNGBDBM32631(Digitonin | NSC23471)
Affinity DataIC50:  9.70E+3nMpH: 7.4 T: 2°CAssay Description:IC50 and maximal activities for inhibition of PhA accumulation were determined from dose-response curves. The accumulation of PhA, a fluorescent ABCG...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Millennium Pharmaceuticals

US Patent
LigandPNGBDBM106158(US9695174, 8A)
Affinity DataIC50: >1.00E+4nMpH: 7.4 T: 2°CAssay Description:To determine potency of compounds on inhibition of transporters, bi-directional transport studies are performed in Caco-2 cells (American Type Cultur...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Millennium Pharmaceuticals

US Patent
LigandPNGBDBM106157(US9695174, 8)
Affinity DataIC50: >1.00E+4nMpH: 7.4 T: 2°CAssay Description:To determine potency of compounds on inhibition of transporters, bi-directional transport studies are performed in Caco-2 cells (American Type Cultur...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Millennium Pharmaceuticals

US Patent
LigandPNGBDBM106209(US9695174, 4)
Affinity DataIC50: >1.00E+4nMpH: 7.4 T: 2°CAssay Description:To determine potency of compounds on inhibition of transporters, bi-directional transport studies are performed in Caco-2 cells (American Type Cultur...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Millennium Pharmaceuticals

US Patent
LigandPNGBDBM106216(US9695174, 12A)
Affinity DataIC50: >1.00E+4nMpH: 7.4 T: 2°CAssay Description:To determine potency of compounds on inhibition of transporters, bi-directional transport studies are performed in Caco-2 cells (American Type Cultur...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Millennium Pharmaceuticals

US Patent
LigandPNGBDBM32619(Botryllamide B, 2)
Affinity DataIC50:  1.12E+4nMpH: 7.4 T: 2°CAssay Description:IC50 and maximal activities for inhibition of PhA accumulation were determined from dose-response curves. The accumulation of PhA, a fluorescent ABCG...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Millennium Pharmaceuticals

US Patent
LigandPNGBDBM32638(Dihydroergocristine | NSC409663)
Affinity DataIC50:  1.18E+4nMpH: 7.4 T: 2°CAssay Description:IC50 and maximal activities for inhibition of PhA accumulation were determined from dose-response curves. The accumulation of PhA, a fluorescent ABCG...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Millennium Pharmaceuticals

US Patent
LigandPNGBDBM32621(Botryllamide D, 4)
Affinity DataIC50:  1.64E+4nMpH: 7.4 T: 2°CAssay Description:IC50 and maximal activities for inhibition of PhA accumulation were determined from dose-response curves. The accumulation of PhA, a fluorescent ABCG...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Millennium Pharmaceuticals

US Patent
LigandPNGBDBM32623(Botryllamide F, 6 | US8470888, Botryllamide F)
Affinity DataIC50:  1.67E+4nMpH: 7.4 T: 2°CAssay Description:IC50 and maximal activities for inhibition of PhA accumulation were determined from dose-response curves. The accumulation of PhA, a fluorescent ABCG...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Millennium Pharmaceuticals

US Patent
LigandPNGBDBM32622(Botryllamide E, 5 | US8470888, Botryllamide I)
Affinity DataIC50:  2.33E+4nMpH: 7.4 T: 2°CAssay Description:IC50 and maximal activities for inhibition of PhA accumulation were determined from dose-response curves. The accumulation of PhA, a fluorescent ABCG...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Millennium Pharmaceuticals

US Patent
LigandPNGBDBM32625(Botryllamide H, 8 | Botryllamide J, 10)
Affinity DataIC50:  2.69E+4nMpH: 7.4 T: 2°CAssay Description:IC50 and maximal activities for inhibition of PhA accumulation were determined from dose-response curves. The accumulation of PhA, a fluorescent ABCG...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Millennium Pharmaceuticals

US Patent
LigandPNGBDBM32617(Botryllamide A, 1 | US8470888, Botryllamide A)
Affinity DataIC50:  3.34E+4nMpH: 7.4 T: 2°CAssay Description:IC50 and maximal activities for inhibition of PhA accumulation were determined from dose-response curves. The accumulation of PhA, a fluorescent ABCG...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Millennium Pharmaceuticals

US Patent
LigandPNGBDBM32626(Botryllamide I, 9)
Affinity DataIC50:  4.14E+4nMpH: 7.4 T: 2°CAssay Description:IC50 and maximal activities for inhibition of PhA accumulation were determined from dose-response curves. The accumulation of PhA, a fluorescent ABCG...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Millennium Pharmaceuticals

US Patent
LigandPNGBDBM32620(Botryllamide C, 3 | US8470888, Botryllamide D)
Affinity DatapH: 7.4 T: 2°CAssay Description:IC50 and maximal activities for inhibition of PhA accumulation were determined from dose-response curves. The accumulation of PhA, a fluorescent ABCG...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Millennium Pharmaceuticals

US Patent
LigandPNGBDBM32625(Botryllamide H, 8 | Botryllamide J, 10)
Affinity DatapH: 7.4 T: 2°CAssay Description:IC50 and maximal activities for inhibition of PhA accumulation were determined from dose-response curves. The accumulation of PhA, a fluorescent ABCG...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed