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Found 117 of ph data with Target = 'Hematopoietic prostaglandin D synthase'
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))
Cayman Chemical

US Patent
LigandPNGBDBM179403(US9126973, 8)
Affinity DataIC50:  4nMpH: 8.0 T: 2°CAssay Description:The assay is carried out by the following steps: 1. Inhibitor screening is performed in 100 mM Tris-HCl, pH 8.0 containing 1 mM GSH, 1 mM MgCl.sub.2,...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))
Cayman Chemical

US Patent
LigandPNGBDBM179422(US9126973, 19)
Affinity DataIC50:  6nMpH: 8.0 T: 2°CAssay Description:The assay is carried out by the following steps: 1. Inhibitor screening is performed in 100 mM Tris-HCl, pH 8.0 containing 1 mM GSH, 1 mM MgCl.sub.2,...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))
Cayman Chemical

US Patent
LigandPNGBDBM250507(US9469627, 2)
Affinity DataIC50:  11nMpH: 7.4Assay Description:I. Assay Solutions a. Preparation of 0.1M K2HPO4/KH2PO4 buffer (pH 7.4) Prepare 0.1 M KH2PO4 from 1M KH2PO4 (Sigma, Cat# P-8709) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))
Cayman Chemical

US Patent
LigandPNGBDBM250506(US9469627, 1)
Affinity DataIC50:  12nMpH: 7.4Assay Description:I. Assay Solutions a. Preparation of 0.1M K2HPO4/KH2PO4 buffer (pH 7.4) Prepare 0.1 M KH2PO4 from 1M KH2PO4 (Sigma, Cat# P-8709) ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))
Cayman Chemical

US Patent
LigandPNGBDBM179375(US9126973, 1)
Affinity DataIC50:  12nMpH: 8.0 T: 2°CAssay Description:The assay is carried out by the following steps: 1. Inhibitor screening is performed in 100 mM Tris-HCl, pH 8.0 containing 1 mM GSH, 1 mM MgCl.sub.2,...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))
Cayman Chemical

US Patent
LigandPNGBDBM124922(US8765750, 7)
Affinity DataIC50:  15nMpH: 8.0Assay Description:The test was carried out according to the method of Urade, Y. et al. (J. Biol. Chem., 262, 3820-3825, (1987)). More specifically, the reaction mixtur...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))
Cayman Chemical

US Patent
LigandPNGBDBM21625(2-phenyl-5-(1H-pyrazol-3-yl)-1,3-thiazole | 2-phen...)
Affinity DataIC50:  21nMpH: 7.2 T: 2°CAssay Description:The PGDS glutathione-S-transferase (GST) activity was measured by using MonoChloroBimane (MCB) as a chromogenic substrate. The assay was run at 384-w...More data for this Ligand-Target Pair
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))
Cayman Chemical

US Patent
LigandPNGBDBM179408(US9126973, 10)
Affinity DataIC50:  21nMpH: 8.0 T: 2°CAssay Description:The assay is carried out by the following steps: 1. Inhibitor screening is performed in 100 mM Tris-HCl, pH 8.0 containing 1 mM GSH, 1 mM MgCl.sub.2,...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))
Cayman Chemical

US Patent
LigandPNGBDBM179418(US9126973, 15)
Affinity DataIC50:  23nMpH: 8.0 T: 2°CAssay Description:The assay is carried out by the following steps: 1. Inhibitor screening is performed in 100 mM Tris-HCl, pH 8.0 containing 1 mM GSH, 1 mM MgCl.sub.2,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))
Cayman Chemical

US Patent
LigandPNGBDBM250508(US9469627, 3)
Affinity DataIC50:  26nMpH: 7.4Assay Description:I. Assay Solutions a. Preparation of 0.1M K2HPO4/KH2PO4 buffer (pH 7.4) Prepare 0.1 M KH2PO4 from 1M KH2PO4 (Sigma, Cat# P-8709) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))
Cayman Chemical

US Patent
LigandPNGBDBM124925(US8765750, 10)
Affinity DataIC50:  27nMpH: 8.0Assay Description:The test was carried out according to the method of Urade, Y. et al. (J. Biol. Chem., 262, 3820-3825, (1987)). More specifically, the reaction mixtur...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))
Cayman Chemical

US Patent
LigandPNGBDBM124918(US8765750, 3)
Affinity DataIC50:  27nMpH: 8.0Assay Description:The test was carried out according to the method of Urade, Y. et al. (J. Biol. Chem., 262, 3820-3825, (1987)). More specifically, the reaction mixtur...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))
Cayman Chemical

US Patent
LigandPNGBDBM124919(US8765750, 4)
Affinity DataIC50:  31nMpH: 8.0Assay Description:The test was carried out according to the method of Urade, Y. et al. (J. Biol. Chem., 262, 3820-3825, (1987)). More specifically, the reaction mixtur...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))
Cayman Chemical

US Patent
LigandPNGBDBM136527(US8865714, 14)
Affinity DataIC50:  32nMpH: 8.0 T: 2°CAssay Description:The test was carried out according to the method of Urade, Y. et al. (J. Biol. Chem., 262, 3820-3825, (1987)). More specifically, the reaction mixtur...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))
Cayman Chemical

US Patent
LigandPNGBDBM136525(US8865714, 12)
Affinity DataIC50:  37nMpH: 8.0 T: 2°CAssay Description:The test was carried out according to the method of Urade, Y. et al. (J. Biol. Chem., 262, 3820-3825, (1987)). More specifically, the reaction mixtur...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))
Cayman Chemical

US Patent
LigandPNGBDBM124926(US8765750, 15)
Affinity DataIC50:  39nMpH: 8.0Assay Description:The test was carried out according to the method of Urade, Y. et al. (J. Biol. Chem., 262, 3820-3825, (1987)). More specifically, the reaction mixtur...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))
Cayman Chemical

US Patent
LigandPNGBDBM136523(US8865714, 10)
Affinity DataIC50:  40nMpH: 8.0 T: 2°CAssay Description:The test was carried out according to the method of Urade, Y. et al. (J. Biol. Chem., 262, 3820-3825, (1987)). More specifically, the reaction mixtur...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))
Cayman Chemical

US Patent
LigandPNGBDBM179409(US9126973, 11)
Affinity DataIC50:  41nMpH: 8.0 T: 2°CAssay Description:The assay is carried out by the following steps: 1. Inhibitor screening is performed in 100 mM Tris-HCl, pH 8.0 containing 1 mM GSH, 1 mM MgCl.sub.2,...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))
Cayman Chemical

US Patent
LigandPNGBDBM124920(US8765750, 5)
Affinity DataIC50:  41nMpH: 8.0Assay Description:The test was carried out according to the method of Urade, Y. et al. (J. Biol. Chem., 262, 3820-3825, (1987)). More specifically, the reaction mixtur...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))
Cayman Chemical

US Patent
LigandPNGBDBM136519(US8865714, 6)
Affinity DataIC50:  43nMpH: 8.0 T: 2°CAssay Description:The test was carried out according to the method of Urade, Y. et al. (J. Biol. Chem., 262, 3820-3825, (1987)). More specifically, the reaction mixtur...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))
Cayman Chemical

US Patent
LigandPNGBDBM136524(US8865714, 11)
Affinity DataIC50:  46nMpH: 8.0 T: 2°CAssay Description:The test was carried out according to the method of Urade, Y. et al. (J. Biol. Chem., 262, 3820-3825, (1987)). More specifically, the reaction mixtur...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))
Cayman Chemical

US Patent
LigandPNGBDBM179401(US9126973, 6)
Affinity DataIC50:  47nMpH: 8.0 T: 2°CAssay Description:The assay is carried out by the following steps: 1. Inhibitor screening is performed in 100 mM Tris-HCl, pH 8.0 containing 1 mM GSH, 1 mM MgCl.sub.2,...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))
Cayman Chemical

US Patent
LigandPNGBDBM124921(US8765750, 6)
Affinity DataIC50:  52nMpH: 8.0Assay Description:The test was carried out according to the method of Urade, Y. et al. (J. Biol. Chem., 262, 3820-3825, (1987)). More specifically, the reaction mixtur...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))
Cayman Chemical

US Patent
LigandPNGBDBM179407(US9126973, 9)
Affinity DataIC50:  53nMpH: 8.0 T: 2°CAssay Description:The assay is carried out by the following steps: 1. Inhibitor screening is performed in 100 mM Tris-HCl, pH 8.0 containing 1 mM GSH, 1 mM MgCl.sub.2,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))
Cayman Chemical

US Patent
LigandPNGBDBM136517(US8865714, 4)
Affinity DataIC50:  54nMpH: 8.0 T: 2°CAssay Description:The test was carried out according to the method of Urade, Y. et al. (J. Biol. Chem., 262, 3820-3825, (1987)). More specifically, the reaction mixtur...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))
Cayman Chemical

US Patent
LigandPNGBDBM136514(US8865714, 1)
Affinity DataIC50:  58nMpH: 8.0 T: 2°CAssay Description:The test was carried out according to the method of Urade, Y. et al. (J. Biol. Chem., 262, 3820-3825, (1987)). More specifically, the reaction mixtur...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))
Cayman Chemical

US Patent
LigandPNGBDBM136529(US8865714, 16)
Affinity DataIC50:  59nMpH: 8.0 T: 2°CAssay Description:The test was carried out according to the method of Urade, Y. et al. (J. Biol. Chem., 262, 3820-3825, (1987)). More specifically, the reaction mixtur...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))
Cayman Chemical

US Patent
LigandPNGBDBM179412(US9126973, 14)
Affinity DataIC50:  59nMpH: 8.0 T: 2°CAssay Description:The assay is carried out by the following steps: 1. Inhibitor screening is performed in 100 mM Tris-HCl, pH 8.0 containing 1 mM GSH, 1 mM MgCl.sub.2,...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))
Cayman Chemical

US Patent
LigandPNGBDBM136530(US8865714, 17)
Affinity DataIC50:  60nMpH: 8.0 T: 2°CAssay Description:The test was carried out according to the method of Urade, Y. et al. (J. Biol. Chem., 262, 3820-3825, (1987)). More specifically, the reaction mixtur...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))
Cayman Chemical

US Patent
LigandPNGBDBM136528(US8865714, 15)
Affinity DataIC50:  60nMpH: 8.0 T: 2°CAssay Description:The test was carried out according to the method of Urade, Y. et al. (J. Biol. Chem., 262, 3820-3825, (1987)). More specifically, the reaction mixtur...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))
Cayman Chemical

US Patent
LigandPNGBDBM124924(US8765750, 9)
Affinity DataIC50:  61nMpH: 8.0Assay Description:The test was carried out according to the method of Urade, Y. et al. (J. Biol. Chem., 262, 3820-3825, (1987)). More specifically, the reaction mixtur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))
Cayman Chemical

US Patent
LigandPNGBDBM136521(US8865714, 8)
Affinity DataIC50:  62nMpH: 8.0 T: 2°CAssay Description:The test was carried out according to the method of Urade, Y. et al. (J. Biol. Chem., 262, 3820-3825, (1987)). More specifically, the reaction mixtur...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))
Cayman Chemical

US Patent
LigandPNGBDBM124916(US8765750, 1)
Affinity DataIC50:  67nMpH: 8.0Assay Description:The test was carried out according to the method of Urade, Y. et al. (J. Biol. Chem., 262, 3820-3825, (1987)). More specifically, the reaction mixtur...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))
Cayman Chemical

US Patent
LigandPNGBDBM136518(US8865714, 5)
Affinity DataIC50:  67nMpH: 8.0 T: 2°CAssay Description:The test was carried out according to the method of Urade, Y. et al. (J. Biol. Chem., 262, 3820-3825, (1987)). More specifically, the reaction mixtur...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))
Cayman Chemical

US Patent
LigandPNGBDBM124927(US8765750, 16)
Affinity DataIC50:  68.4nMpH: 8.0Assay Description:The test was carried out according to the method of Urade, Y. et al. (J. Biol. Chem., 262, 3820-3825, (1987)). More specifically, the reaction mixtur...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))
Cayman Chemical

US Patent
LigandPNGBDBM136520(US8865714, 7)
Affinity DataIC50:  71nMpH: 8.0 T: 2°CAssay Description:The test was carried out according to the method of Urade, Y. et al. (J. Biol. Chem., 262, 3820-3825, (1987)). More specifically, the reaction mixtur...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))
Cayman Chemical

US Patent
LigandPNGBDBM21627(N-[4-methyl-3-({3-[(4-methylpiperazin-1-yl)methyl]...)
Affinity DataIC50:  75nMpH: 7.2 T: 2°CAssay Description:The PGDS glutathione-S-transferase (GST) activity was measured by using MonoChloroBimane (MCB) as a chromogenic substrate. The assay was run at 384-w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))
Cayman Chemical

US Patent
LigandPNGBDBM179411(US9126973, 13)
Affinity DataIC50:  75nMpH: 8.0 T: 2°CAssay Description:The assay is carried out by the following steps: 1. Inhibitor screening is performed in 100 mM Tris-HCl, pH 8.0 containing 1 mM GSH, 1 mM MgCl.sub.2,...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))
Cayman Chemical

US Patent
LigandPNGBDBM136516(US8865714, 3)
Affinity DataIC50:  76nMpH: 8.0 T: 2°CAssay Description:The test was carried out according to the method of Urade, Y. et al. (J. Biol. Chem., 262, 3820-3825, (1987)). More specifically, the reaction mixtur...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))
Cayman Chemical

US Patent
LigandPNGBDBM179382(US9126973, 4)
Affinity DataIC50:  82nMpH: 8.0 T: 2°CAssay Description:The assay is carried out by the following steps: 1. Inhibitor screening is performed in 100 mM Tris-HCl, pH 8.0 containing 1 mM GSH, 1 mM MgCl.sub.2,...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))
Cayman Chemical

US Patent
LigandPNGBDBM179473(US9126973, 49)
Affinity DataIC50:  84nMpH: 8.0 T: 2°CAssay Description:The assay is carried out by the following steps: 1. Inhibitor screening is performed in 100 mM Tris-HCl, pH 8.0 containing 1 mM GSH, 1 mM MgCl.sub.2,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))
Cayman Chemical

US Patent
LigandPNGBDBM136522(US8865714, 9)
Affinity DataIC50:  85nMpH: 8.0 T: 2°CAssay Description:The test was carried out according to the method of Urade, Y. et al. (J. Biol. Chem., 262, 3820-3825, (1987)). More specifically, the reaction mixtur...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))
Cayman Chemical

US Patent
LigandPNGBDBM136515(US8865714, 2)
Affinity DataIC50:  86nMpH: 8.0 T: 2°CAssay Description:The test was carried out according to the method of Urade, Y. et al. (J. Biol. Chem., 262, 3820-3825, (1987)). More specifically, the reaction mixtur...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))
Cayman Chemical

US Patent
LigandPNGBDBM193900(US9199976, 12)
Affinity DataIC50:  86nMpH: 8.0Assay Description:The H-PGDS catalyzed conjugation of GSH and 1-chloro-2,4-dinitrobenzene (CDNB) was used as the biochemical assay for enzyme inhibition. Reactions wer...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))
Cayman Chemical

US Patent
LigandPNGBDBM136526(US8865714, 13)
Affinity DataIC50:  91nMpH: 8.0 T: 2°CAssay Description:The test was carried out according to the method of Urade, Y. et al. (J. Biol. Chem., 262, 3820-3825, (1987)). More specifically, the reaction mixtur...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))
Cayman Chemical

US Patent
LigandPNGBDBM179380(US9126973, 2)
Affinity DataIC50:  97nMpH: 8.0 T: 2°CAssay Description:The assay is carried out by the following steps: 1. Inhibitor screening is performed in 100 mM Tris-HCl, pH 8.0 containing 1 mM GSH, 1 mM MgCl.sub.2,...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))
Cayman Chemical

US Patent
LigandPNGBDBM124939(US8765750, Reference Example 12)
Affinity DataIC50:  106nMpH: 8.0Assay Description:The test was carried out according to the method of Urade, Y. et al. (J. Biol. Chem., 262, 3820-3825, (1987)). More specifically, the reaction mixtur...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))
Cayman Chemical

US Patent
LigandPNGBDBM124939(US8765750, Reference Example 12)
Affinity DataIC50:  106nMpH: 8.0 T: 2°CAssay Description:The test was carried out according to the method of Urade, Y. et al. (J. Biol. Chem., 262, 3820-3825, (1987)). More specifically, the reaction mixtur...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))
Cayman Chemical

US Patent
LigandPNGBDBM179479(US9126973, 54)
Affinity DataIC50:  130nMpH: 8.0 T: 2°CAssay Description:The assay is carried out by the following steps: 1. Inhibitor screening is performed in 100 mM Tris-HCl, pH 8.0 containing 1 mM GSH, 1 mM MgCl.sub.2,...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))
Cayman Chemical

US Patent
LigandPNGBDBM21624(4-{[4-(4-fluoro-3-methylphenyl)-1,3-thiazol-2-yl]a...)
Affinity DataIC50:  138nMpH: 7.2 T: 2°CAssay Description:The PGDS glutathione-S-transferase (GST) activity was measured by using MonoChloroBimane (MCB) as a chromogenic substrate. The assay was run at 384-w...More data for this Ligand-Target Pair
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