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Found 3 of ph data with Target = 'Putative lanosterol 14-alpha-demethylase'
TargetPutative lanosterol 14-alpha-demethylase(Leishmania infantum)
Vanderbilt University

LigandPNGBDBM213823(EPL-BS1246 (UDO))
Affinity DataKd:  156nMpH: 7.4 T: 2°CAssay Description:Briefly, the reaction mixture contained 1 uM CYP51, 2 uM cytochrome P450 reductase, 100 uM dilauroyl-alpha-phosphatidylcholine, 0.4 mg/ml isoctrate d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetPutative lanosterol 14-alpha-demethylase(Leishmania infantum)
Vanderbilt University

LigandPNGBDBM213824(Posaconazole)
Affinity DataKd:  18nMpH: 7.4 T: 2°CAssay Description:Briefly, the reaction mixture contained 1 uM CYP51, 2 uM cytochrome P450 reductase, 100 uM dilauroyl-alpha-phosphatidylcholine, 0.4 mg/ml isoctrate d...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPutative lanosterol 14-alpha-demethylase(Leishmania infantum)
Vanderbilt University

LigandPNGBDBM213822(EPL-BS0967 (UDD))
Affinity DataKd:  419nMpH: 7.4 T: 2°CAssay Description:Briefly, the reaction mixture contained 1 uM CYP51, 2 uM cytochrome P450 reductase, 100 uM dilauroyl-alpha-phosphatidylcholine, 0.4 mg/ml isoctrate d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed