Compile Data Set for Download or QSAR
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Found 7 of affinity data with PDB=3B3O
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
University of California Irvine

LigandPNGBDBM29234(CHEMBL481815 | US9090589, 6 | aminopyridine-pyrrol...)
Affinity DataKi:  85nM ΔG°:  -41.0kJ/molepH: 7.5 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
University of California Irvine

LigandPNGBDBM29234(CHEMBL481815 | US9090589, 6 | aminopyridine-pyrrol...)
Affinity DataKi:  85nMAssay Description:Inhibition of rat recombinant nNOS expressed in Escherichia coli by hemoglobin capture assayMore data for this Ligand-Target Pair
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Northwestern University

US Patent
LigandPNGBDBM29234(CHEMBL481815 | US9090589, 6 | aminopyridine-pyrrol...)
Affinity DataKi:  85nMAssay Description:Recombinant NOS isozymes over-expressed in E. coli were utilized. (Ji, H., et al., Discovery of highly potent and selective inhibitors of neuronal ni...More data for this Ligand-Target Pair
TargetNitric oxide synthase, brain [D597N,M336V](Rattus norvegicus (rat))
University of California Irvine

LigandPNGBDBM29234(CHEMBL481815 | US9090589, 6 | aminopyridine-pyrrol...)
Affinity DataKi:  1.20E+3nM ΔG°:  -34.4kJ/molepH: 7.5 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
University of California Irvine

LigandPNGBDBM29234(CHEMBL481815 | US9090589, 6 | aminopyridine-pyrrol...)
Affinity DataKi:  8.95E+3nMAssay Description:Inhibition of rat recombinant nNOSMore data for this Ligand-Target Pair
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
University of California Irvine

LigandPNGBDBM29234(CHEMBL481815 | US9090589, 6 | aminopyridine-pyrrol...)
Affinity DataIC50:  740nMAssay Description:Inhibition of recombinant rat nNOS expressed in Escherichia coli by hemoglobin capture assayMore data for this Ligand-Target Pair
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
University of California Irvine

LigandPNGBDBM29234(CHEMBL481815 | US9090589, 6 | aminopyridine-pyrrol...)
Affinity DataIC50:  4.20E+4nMAssay Description:Inhibition of rat nNOS expressed in HEK293T cells preincubated for 30 mins prior A23187-induced activation measured after 6 hrs by Griess assayMore data for this Ligand-Target Pair