Compile Data Set for Download or QSAR
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Found 3
TargetPhosphodiesterase(Leishmania major)
Vu University Amsterdam

Curated by ChEMBL
LigandPNGBDBM50397078(CHEMBL2171452)
Affinity DataIC50:  130nMAssay Description:Inhibition of Leishmania major recombinant PDEB1 expressed in Sf21 insect cells assessed as reduction of [3H]-cAMP hydrolysis by scintillation proxim...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Leishmania major)
Vu University Amsterdam

Curated by ChEMBL
LigandPNGBDBM50027176(2-Acetoxy-Benzoic Acid | 3-Isobutyl-Methylxanthine...)
Affinity DataIC50:  5.80E+5nMAssay Description:Inhibition of Leishmania major PDEB1 catalytic domain (582 to 940 residues) expressed in Escherichia coli BL21-CodonPlus cells using [3H]cGMP or [3H]...More data for this Ligand-Target Pair
TargetPhosphodiesterase(Leishmania major)
Vu University Amsterdam

Curated by ChEMBL
LigandPNGBDBM50027176(2-Acetoxy-Benzoic Acid | 3-Isobutyl-Methylxanthine...)
Affinity DataIC50:  5.80E+5nMAssay Description:Inhibition of Leishmania major PDEB1 catalytic domain (582 to 940 residues) expressed in Escherichia coli BL21-CodonPlus cells using [3H]cGMP or [3H]...More data for this Ligand-Target Pair