Compile Data Set for Download or QSAR
maximum 50k data
Found 225 of ec50 data for polymerid = 1913,7651,50004608
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))TBA
LigandPNGBDBM50610369(CHEMBL5277174)
Affinity DataEC50:  5.60nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))TBA
LigandPNGBDBM50610353(CHEMBL5270898)
Affinity DataEC50:  9.60nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))TBA
LigandPNGBDBM50610353(CHEMBL5270898)
Affinity DataEC50:  13nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))TBA
LigandPNGBDBM50610342(CHEMBL5266290)
Affinity DataEC50:  29nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))TBA
LigandPNGBDBM50610368(CHEMBL5283935)
Affinity DataEC50:  30nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))TBA
LigandPNGBDBM50610351(CHEMBL5272738)
Affinity DataEC50:  40nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))TBA
LigandPNGBDBM50610352(CHEMBL5290073)
Affinity DataEC50:  58nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))TBA
LigandPNGBDBM50610348(CHEMBL5276122)
Affinity DataEC50:  63nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))TBA
LigandPNGBDBM50610350(CHEMBL5276663)
Affinity DataEC50:  70nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))TBA
LigandPNGBDBM50610345(CHEMBL5291224)
Affinity DataEC50:  72nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))TBA
LigandPNGBDBM50610337(CHEMBL5271750)
Affinity DataEC50:  75nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))TBA
LigandPNGBDBM50610367(CHEMBL5280450)
Affinity DataEC50:  79nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))TBA
LigandPNGBDBM50610374(CHEMBL4561657)
Affinity DataEC50:  90nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))TBA
LigandPNGBDBM50610347(CHEMBL5287675)
Affinity DataEC50:  100nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))TBA
LigandPNGBDBM50610365(CHEMBL5289154)
Affinity DataEC50:  120nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))TBA
LigandPNGBDBM50610349(CHEMBL5288960)
Affinity DataEC50:  130nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))TBA
LigandPNGBDBM50610338(CHEMBL5265984)
Affinity DataEC50:  150nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))TBA
LigandPNGBDBM50610372(CHEMBL5282146)
Affinity DataEC50:  150nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))TBA
LigandPNGBDBM50610346(CHEMBL5287219)
Affinity DataEC50:  170nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))TBA
LigandPNGBDBM50610341(CHEMBL5278339)
Affinity DataEC50:  170nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))TBA
LigandPNGBDBM50610364(CHEMBL5289693)
Affinity DataEC50:  220nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))TBA
LigandPNGBDBM50610366(CHEMBL5290054)
Affinity DataEC50:  250nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))TBA
LigandPNGBDBM50182801((3R,4R,5R)-5-(Hydroxymethyl)piperidine-3,4-diol, 8...)
Affinity DataEC50:  300nMMore data for this Ligand-Target Pair
In DepthDetails PDB3D3D Structure (crystal)
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))TBA
LigandPNGBDBM50610357(CHEMBL5287823)
Affinity DataEC50:  360nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))TBA
LigandPNGBDBM50182801((3R,4R,5R)-5-(Hydroxymethyl)piperidine-3,4-diol, 8...)
Affinity DataEC50:  390nMMore data for this Ligand-Target Pair
In DepthDetails PDB3D3D Structure (crystal)
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))TBA
LigandPNGBDBM50610373(CHEMBL5285193)
Affinity DataEC50:  410nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))TBA
LigandPNGBDBM50610339(CHEMBL5271587)
Affinity DataEC50:  440nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))TBA
LigandPNGBDBM50610358(CHEMBL5272952)
Affinity DataEC50:  460nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))TBA
LigandPNGBDBM50610371(CHEMBL5267578)
Affinity DataEC50:  540nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))TBA
LigandPNGBDBM50610340(CHEMBL5272591)
Affinity DataEC50:  630nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))TBA
LigandPNGBDBM50610360(CHEMBL5283330)
Affinity DataEC50:  660nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))TBA
LigandPNGBDBM50610362(CHEMBL5270914)
Affinity DataEC50:  680nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))TBA
LigandPNGBDBM50537912(CHEMBL4649463)
Affinity DataEC50:  700nMAssay Description:Chaperone activity at GCase in wild-type human fibroblasts assessed as increase in GPN-induced reduction of calcium release using Fluo-8AM based fluo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))TBA
LigandPNGBDBM50537914(CHEMBL4636676)
Affinity DataEC50:  1.10E+3nMAssay Description:Chaperone activity at GCase in wild-type human fibroblasts assessed as increase in GPN-induced reduction of calcium release using Fluo-8AM based fluo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))TBA
LigandPNGBDBM50537911(CHEMBL4635139)
Affinity DataEC50:  1.10E+3nMAssay Description:Chaperone activity at GCase in wild-type human fibroblasts assessed as increase in GPN-induced reduction of calcium release using Fluo-8AM based fluo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))TBA
LigandPNGBDBM50537913(CHEMBL4647988)
Affinity DataEC50:  1.10E+3nMAssay Description:Chaperone activity at GCase in wild-type human fibroblasts assessed as increase in GPN-induced reduction of calcium release using Fluo-8AM based fluo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))TBA
LigandPNGBDBM50610344(CHEMBL5279401)
Affinity DataEC50:  1.40E+3nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))TBA
LigandPNGBDBM42405(MLS000110376 | N-(2-piperazin-1-yl-1,2-dihydroacen...)
Affinity DataEC50:  1.67E+3nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))TBA
LigandPNGBDBM50610359(CHEMBL5289722)
Affinity DataEC50:  1.80E+3nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))TBA
LigandPNGBDBM50610361(CHEMBL5279069)
Affinity DataEC50:  2.10E+3nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetLysosomal acid glucosylceramidase(Mus musculus (Mouse))
Amicus Therapeutics

US Patent
LigandPNGBDBM175512(US9119845, 13)
Affinity DataKi:  3.11E+3nM IC50:  7.50E+3nM EC50:  2.20E+3nMpH: 4.5Assay Description:To 2.5 μl of supernatant (in 96-well plates) was added 17.5 μl reaction buffer (citrate phosphate buffer, pH 4.5, no Triton X-100), and 50 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))TBA
LigandPNGBDBM30765(2-amino-1-(2-methylpropyl)-N-(thiophen-2-ylmethyl)...)
Affinity DataEC50:  2.49E+3nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))TBA
LigandPNGBDBM20607((2-{4-[(1Z)-1,2-diphenylbut-1-en-1-yl]phenoxy}ethy...)
Affinity DataEC50:  2.50E+3nMAssay Description:Chaperone activity at GCase in wild-type human fibroblasts assessed as increase in GPN-induced reduction of calcium release using Fluo-8AM based fluo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))TBA
LigandPNGBDBM42310(2,3-dihydro-1,4-benzodioxin-3-ylmethyl-methyl-[2-(...)
Affinity DataEC50:  2.65E+3nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))TBA
LigandPNGBDBM50610343(CHEMBL5275563)
Affinity DataEC50:  5.20E+3nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))TBA
LigandPNGBDBM50610354(CHEMBL5268346)
Affinity DataEC50:  5.30E+3nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))TBA
LigandPNGBDBM50610370(CHEMBL5285901)
Affinity DataEC50:  6.01E+3nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))TBA
LigandPNGBDBM50610355(CHEMBL5266397)
Affinity DataEC50:  6.80E+3nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetLysosomal acid glucosylceramidase(Mus musculus (Mouse))
Amicus Therapeutics

US Patent
LigandPNGBDBM175515(US9119845, 16)
Affinity DataKi:  440nM IC50:  1.07E+3nM EC50:  6.90E+3nMpH: 4.5Assay Description:To 2.5 μl of supernatant (in 96-well plates) was added 17.5 μl reaction buffer (citrate phosphate buffer, pH 4.5, no Triton X-100), and 50 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))TBA
LigandPNGBDBM50610356(CHEMBL5272210)
Affinity DataEC50:  7.10E+3nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
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