Compile Data Set for Download or QSAR
maximum 50k data
Found 14 of ec50 data for polymerid = 343,50001120
TargetSmall conductance calcium-activated potassium channel protein 3(Homo sapiens (Human))
Universidad Nacional Aut£Noma De M£Xico

Curated by ChEMBL
LigandPNGBDBM50561185(CHEMBL4749661)
Affinity DataEC50:  0.360nMAssay Description:Inhibition of recombinant human SK3 expressed in HEK293T cells assessed as reduction in channel current with holding potential 0 mV and ramp voltage ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmall conductance calcium-activated potassium channel protein 3(Homo sapiens (Human))
Universidad Nacional Aut£Noma De M£Xico

Curated by ChEMBL
LigandPNGBDBM50561188(CHEMBL4785313)
Affinity DataEC50:  0.380nMAssay Description:Inhibition of recombinant human SK3 expressed in HEK293T cells assessed as reduction in channel current with holding potential 0 mV and ramp voltage ...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetSmall conductance calcium-activated potassium channel protein 3(Homo sapiens (Human))
Universidad Nacional Aut£Noma De M£Xico

Curated by ChEMBL
LigandPNGBDBM50561184(CHEMBL4762592)
Affinity DataEC50:  1.10nMAssay Description:Inhibition of recombinant human SK3 expressed in HEK293T cells assessed as decrease in intracellular calcium level at membrane potential -120 mV for ...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetSmall conductance calcium-activated potassium channel protein 3(Homo sapiens (Human))
Universidad Nacional Aut£Noma De M£Xico

Curated by ChEMBL
LigandPNGBDBM50561185(CHEMBL4749661)
Affinity DataEC50:  1.10nMAssay Description:Inhibition of recombinant human SK3 expressed in HEK293T cells assessed as decrease in intracellular calcium level at membrane potential -120 mV for ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmall conductance calcium-activated potassium channel protein 3(Homo sapiens (Human))
Universidad Nacional Aut£Noma De M£Xico

Curated by ChEMBL
LigandPNGBDBM50561183(CHEMBL4787693)
Affinity DataEC50:  1.70nMAssay Description:Inhibition of recombinant human SK3 expressed in HEK293T cells assessed as decrease in intracellular calcium level at membrane potential -120 mV for ...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetSmall conductance calcium-activated potassium channel protein 3(Homo sapiens (Human))
Universidad Nacional Aut£Noma De M£Xico

Curated by ChEMBL
LigandPNGBDBM50561187(CHEMBL4786321)
Affinity DataEC50:  2.60nMAssay Description:Inhibition of recombinant human SK3 expressed in HEK293T cells assessed as reduction in channel current with holding potential 0 mV and ramp voltage ...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetSmall conductance calcium-activated potassium channel protein 3(Homo sapiens (Human))
Universidad Nacional Aut£Noma De M£Xico

Curated by ChEMBL
LigandPNGBDBM50561186(CHEMBL4760396)
Affinity DataEC50:  3.80nMAssay Description:Inhibition of recombinant human SK3 expressed in HEK293T cells assessed as decrease in intracellular calcium level at membrane potential -120 mV for ...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetSmall conductance calcium-activated potassium channel protein 3(Homo sapiens (Human))
Universidad Nacional Aut£Noma De M£Xico

Curated by ChEMBL
LigandPNGBDBM50426576(CHEMBL2324346)
Affinity DataEC50:  20nMAssay Description:Inhibition of human Kca 2.3 expressed in HEK293 cells by patch clamp techniqueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmall conductance calcium-activated potassium channel protein 3(Homo sapiens (Human))
Universidad Nacional Aut£Noma De M£Xico

Curated by ChEMBL
LigandPNGBDBM50583211(CHEMBL5078247)
Affinity DataEC50:  190nMAssay Description:Potentiation of human KCa2.3 expressed in HEK293 cells at -90 mV holding potential measured at 1 to 2 days by patch clamp electrophysiology relative ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmall conductance calcium-activated potassium channel protein 3(Homo sapiens (Human))
Universidad Nacional Aut£Noma De M£Xico

Curated by ChEMBL
LigandPNGBDBM50263331((1H-Benzoimidazol-2-yl)-(R)-1,2,3,4-tetrahydronaph...)
Affinity DataEC50:  400nMAssay Description:Inhibition of wild type human SK3 channel expressed in HEK293 cells assessed as Ca2+ sensitivity by inside-out patch clamp techniqueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmall conductance calcium-activated potassium channel protein 3(Homo sapiens (Human))
Universidad Nacional Aut£Noma De M£Xico

Curated by ChEMBL
LigandPNGBDBM50583213(CHEMBL5086997)
Affinity DataEC50:  600nMAssay Description:Potentiation of human KCa2.3 expressed in HEK293 cells at -90 mV holding potential measured at 1 to 2 days by patch clamp electrophysiologyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmall conductance calcium-activated potassium channel protein 3(Homo sapiens (Human))
Universidad Nacional Aut£Noma De M£Xico

Curated by ChEMBL
LigandPNGBDBM50275090((1H-Benzoimidazol-2-yl)-(6,7-dichloro-1,2,3,4-tetr...)
Affinity DataEC50:  1.81E+3nMAssay Description:Inhibition of wild type human SK3 channel expressed in HEK293 cells assessed as Ca2+ sensitivity by inside-out patch clamp techniqueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmall conductance calcium-activated potassium channel protein 3(Homo sapiens (Human))
Universidad Nacional Aut£Noma De M£Xico

Curated by ChEMBL
LigandPNGBDBM50263331((1H-Benzoimidazol-2-yl)-(R)-1,2,3,4-tetrahydronaph...)
Affinity DataEC50:  2.20E+3nMAssay Description:Inhibition of wild type human SK3 channel expressed in HEK293 cells assessed as Ca2+ sensitivity by inside-out patch clamp technique in presence of 5...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmall conductance calcium-activated potassium channel protein 3(Homo sapiens (Human))
Universidad Nacional Aut£Noma De M£Xico

Curated by ChEMBL
LigandPNGBDBM168436(US9675591, SKA-19)
Affinity DataEC50:  1.50E+4nMpH: 7.35 T: 2°CAssay Description:All experiments were conducted at room temperature (22-24° C.) with an EPC-10 amplifier and Pulse software (HEKA, Lambrecht/Pfalz, Germany) in the wh...More data for this Ligand-Target Pair
In DepthDetails US Patent