Compile Data Set for Download or QSAR
maximum 50k data
Found 180 of ic50 data for polymerid = 1568,50004998
TargetVitamin K-dependent protein C(Homo sapiens (Human))
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50193234(CHEMBL211973 | {(R)-1-[2-(4-carbamimidoyl-benzylca...)
Affinity DataIC50:  100nMAssay Description:Inhibition of human aPCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin K-dependent protein C(Homo sapiens (Human))
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50447515(CHEMBL3115901)
Affinity DataIC50:  130nMAssay Description:Inhibition of human APC using S-2366 as substrate preincubated for 300 seconds followed by substrate addition measured after 40 mins by spectrophotom...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin K-dependent protein C(Homo sapiens (Human))
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50138156(Biphenyl-4-carboxylic acid {1-[(3-aminomethyl-phen...)
Affinity DataIC50: >130nMAssay Description:Compound was tested for inhibition of human activated protein C (APC)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin K-dependent protein C(Homo sapiens (Human))
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50138161(CHEMBL321466 | N-{1-[(3-Aminomethyl-phenylcarbamoy...)
Affinity DataIC50: >170nMAssay Description:Compound was tested for inhibition of human activated protein C (APC)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin K-dependent protein C(Homo sapiens (Human))
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50193230(CHEMBL215639 | {(R)-1-[2-(4-carbamimidoyl-benzylca...)
Affinity DataIC50:  250nMAssay Description:Inhibition of human aPCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin K-dependent protein C(Homo sapiens (Human))
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50447516(CHEMBL3115900)
Affinity DataIC50:  260nMAssay Description:Inhibition of human APC using S-2366 as substrate preincubated for 300 seconds followed by substrate addition measured after 40 mins by spectrophotom...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin K-dependent protein C(Homo sapiens (Human))
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50193224(((R)-1-{[(S)-(4-carbamimidoyl-benzylcarbamoyl)-ind...)
Affinity DataIC50:  350nMAssay Description:Inhibition of human aPCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin K-dependent protein C(Homo sapiens (Human))
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50193229(CHEMBL215357 | {(R)-1-[2-(4-carbamimidoyl-benzylca...)
Affinity DataIC50:  430nMAssay Description:Inhibition of human aPCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin K-dependent protein C(Homo sapiens (Human))
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50138154(Biphenyl-4-carboxylic acid {1-[(5-aminomethyl-2-me...)
Affinity DataIC50: >450nMAssay Description:Compound was tested for inhibition of human activated protein C (APC)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin K-dependent protein C(Homo sapiens (Human))
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50447528(CHEMBL3115904)
Affinity DataIC50:  470nMAssay Description:Inhibition of human APC using S-2366 as substrate preincubated for 300 seconds followed by substrate addition measured after 40 mins by spectrophotom...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin K-dependent protein C(Homo sapiens (Human))
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50447523(CHEMBL3115897)
Affinity DataIC50:  670nMAssay Description:Inhibition of human APC using S-2366 as substrate preincubated for 300 seconds followed by substrate addition measured after 40 mins by spectrophotom...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin K-dependent protein C(Homo sapiens (Human))
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50193242(CHEMBL212789 | {(R)-1-[(S)-1-(4-carbamimidoyl-benz...)
Affinity DataIC50:  710nMAssay Description:Inhibition of human aPCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin K-dependent protein C(Homo sapiens (Human))
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50193241(CHEMBL380157 | {(R)-1-[2-(4-carbamimidoyl-benzylca...)
Affinity DataIC50:  750nMAssay Description:Inhibition of human aPCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin K-dependent protein C(Homo sapiens (Human))
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50193240(CHEMBL426333 | {(R)-1-[2-(4-carbamimidoyl-benzylca...)
Affinity DataIC50:  800nMAssay Description:Inhibition of human aPCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin K-dependent protein C(Homo sapiens (Human))
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50193243(({(R)-[2-(4-carbamimidoyl-benzylcarbamoyl)-indan-2...)
Affinity DataIC50:  820nMAssay Description:Inhibition of human aPCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin K-dependent protein C(Homo sapiens (Human))
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50138157(Biphenyl-4-carboxylic acid {1-[(5-aminomethyl-2-ch...)
Affinity DataIC50: >870nMAssay Description:Compound was tested for inhibition of human activated protein C (APC)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin K-dependent protein C(Homo sapiens (Human))
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50447517(CHEMBL3115894)
Affinity DataIC50:  920nMAssay Description:Inhibition of human APC using S-2366 as substrate preincubated for 300 seconds followed by substrate addition measured after 40 mins by spectrophotom...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin K-dependent protein C(Homo sapiens (Human))
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50447521(CHEMBL3115899)
Affinity DataIC50:  980nMAssay Description:Inhibition of human APC using S-2366 as substrate preincubated for 300 seconds followed by substrate addition measured after 40 mins by spectrophotom...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin K-dependent protein C(Homo sapiens (Human))
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50193235(CHEMBL215870 | {(R)-1-[6-(4-carbamimidoyl-benzylca...)
Affinity DataIC50:  1.07E+3nMAssay Description:Inhibition of human aPCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin K-dependent protein C(Homo sapiens (Human))
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50447522(CHEMBL3115898)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of human APC using S-2366 as substrate preincubated for 300 seconds followed by substrate addition measured after 40 mins by spectrophotom...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin K-dependent protein C(Homo sapiens (Human))
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50447514(CHEMBL3115903)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of human APC using S-2366 as substrate preincubated for 300 seconds followed by substrate addition measured after 40 mins by spectrophotom...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin K-dependent protein C(Homo sapiens (Human))
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50193228(CHEMBL215556 | {(R)-1-[2-(4-carbamimidoyl-benzylca...)
Affinity DataIC50:  1.12E+3nMAssay Description:Inhibition of human aPCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin K-dependent protein C(Homo sapiens (Human))
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50193235(CHEMBL215870 | {(R)-1-[6-(4-carbamimidoyl-benzylca...)
Affinity DataIC50:  1.14E+3nMAssay Description:Inhibition of human aPCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin K-dependent protein C(Homo sapiens (Human))
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50447525(CHEMBL3115893)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of human APC using S-2366 as substrate preincubated for 300 seconds followed by substrate addition measured after 40 mins by spectrophotom...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin K-dependent protein C(Homo sapiens (Human))
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM29388(Exanta | Melagatran | US11584714, Compound 999)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of human APC using S-2366 as substrate preincubated for 300 seconds followed by substrate addition measured after 40 mins by spectrophotom...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin K-dependent protein C(Homo sapiens (Human))
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50447527(CHEMBL3115905)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of human APC using S-2366 as substrate preincubated for 300 seconds followed by substrate addition measured after 40 mins by spectrophotom...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin K-dependent protein C(Homo sapiens (Human))
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50193232(CHEMBL448732 | {(R)-1-[6-(4-carbamimidoyl-benzylca...)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of human aPCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin K-dependent protein C(Homo sapiens (Human))
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50193243(({(R)-[2-(4-carbamimidoyl-benzylcarbamoyl)-indan-2...)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of human APC using S-2366 as substrate preincubated for 300 seconds followed by substrate addition measured after 40 mins by spectrophotom...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor V(Homo sapiens (Human))
Maastricht University

Curated by ChEMBL
LigandPNGBDBM50376425(CHEMBL1162108)
Affinity DataIC50:  1.81E+3nMAssay Description:Inhibition of factor 5a-mediated prothrombin activation in human plasma by prothrombinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin K-dependent protein C(Homo sapiens (Human))
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50193222(2-{[(1R)-1-[(2-{[(4-carbamimidoylphenyl)methyl]car...)
Affinity DataIC50:  2.04E+3nMAssay Description:Inhibition of human aPCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor V(Homo sapiens (Human))
Maastricht University

Curated by ChEMBL
LigandPNGBDBM50376418(CHEMBL259312)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of human factor 5a light chain binding to immobilized phospholipid by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin K-dependent protein C(Homo sapiens (Human))
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50447519(CHEMBL3115906)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of human APC using S-2366 as substrate preincubated for 300 seconds followed by substrate addition measured after 40 mins by spectrophotom...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin K-dependent protein C(Homo sapiens (Human))
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50447524(CHEMBL3115896)
Affinity DataIC50:  3.10E+3nMAssay Description:Inhibition of human APC using S-2366 as substrate preincubated for 300 seconds followed by substrate addition measured after 40 mins by spectrophotom...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin K-dependent protein C(Homo sapiens (Human))
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50447518(CHEMBL3115892)
Affinity DataIC50:  3.10E+3nMAssay Description:Inhibition of human APC using S-2366 as substrate preincubated for 300 seconds followed by substrate addition measured after 40 mins by spectrophotom...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor V(Homo sapiens (Human))
Maastricht University

Curated by ChEMBL
LigandPNGBDBM50376418(CHEMBL259312)
Affinity DataIC50:  3.51E+3nMAssay Description:Inhibition of human recombinant factor 5a C2 domain binding to immobilized phospholipid by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin K-dependent protein C(Homo sapiens (Human))
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50114455(2'-Sulfamoyl-biphenyl-4-carboxylic acid [2-(3-carb...)
Affinity DataIC50:  3.70E+3nMAssay Description:Tested in vitro for the inhibitory activity against activated protein C (APC)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin K-dependent protein C(Homo sapiens (Human))
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50447520(CHEMBL3115902)
Affinity DataIC50:  3.80E+3nMAssay Description:Inhibition of human APC using S-2366 as substrate preincubated for 300 seconds followed by substrate addition measured after 40 mins by spectrophotom...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor V(Homo sapiens (Human))
Maastricht University

Curated by ChEMBL
LigandPNGBDBM50376419(CHEMBL1162109)
Affinity DataIC50:  3.80E+3nMAssay Description:Inhibition of factor 5a-mediated prothrombin activation in human plasma by prothrombinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin K-dependent protein C(Homo sapiens (Human))
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50193238(CHEMBL213120 | {(R)-1-[2-(4-carbamimidoyl-benzylca...)
Affinity DataIC50:  3.83E+3nMAssay Description:Inhibition of human aPCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor V(Homo sapiens (Human))
Maastricht University

Curated by ChEMBL
LigandPNGBDBM50376423(CHEMBL410427)
Affinity DataIC50:  4.80E+3nMAssay Description:Inhibition of human factor 5a light chain binding to immobilized phospholipid by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor V(Homo sapiens (Human))
Maastricht University

Curated by ChEMBL
LigandPNGBDBM50376423(CHEMBL410427)
Affinity DataIC50:  5.53E+3nMAssay Description:Inhibition of human recombinant factor 5a C2 domain binding to immobilized phospholipid by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin K-dependent protein C(Homo sapiens (Human))
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50447526(CHEMBL3115907)
Affinity DataIC50:  5.60E+3nMAssay Description:Inhibition of human APC using S-2366 as substrate preincubated for 300 seconds followed by substrate addition measured after 40 mins by spectrophotom...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin K-dependent protein C(Homo sapiens (Human))
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50124984((R)-5-Guanidino-2-phenylmethanesulfonylamino-penta...)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibitory activity against activated protein C (aPC)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin K-dependent protein C(Homo sapiens (Human))
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50106057(3-Carbamimidoyl-N-[(R)-phenyl-(2'-sulfamoyl-biphen...)
Affinity DataIC50:  6.56E+3nMAssay Description:Inhibitory activity of the compound against activated protein C (APC)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor V(Homo sapiens (Human))
Maastricht University

Curated by ChEMBL
LigandPNGBDBM50376422(CHEMBL265687)
Affinity DataIC50:  6.71E+3nMAssay Description:Inhibition of human recombinant factor 5a C2 domain binding to immobilized phospholipid by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor V(Homo sapiens (Human))
Maastricht University

Curated by ChEMBL
LigandPNGBDBM50376421(CHEMBL410426)
Affinity DataIC50:  7.40E+3nMAssay Description:Inhibition of human recombinant factor 5a C2 domain binding to immobilized phospholipid by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor V(Homo sapiens (Human))
Maastricht University

Curated by ChEMBL
LigandPNGBDBM50376421(CHEMBL410426)
Affinity DataIC50:  8.55E+3nMAssay Description:Inhibition of human factor 5a light chain binding to immobilized phospholipid by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor V(Homo sapiens (Human))
Maastricht University

Curated by ChEMBL
LigandPNGBDBM50376422(CHEMBL265687)
Affinity DataIC50:  8.56E+3nMAssay Description:Inhibition of human factor 5a light chain binding to immobilized phospholipid by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor V(Homo sapiens (Human))
Maastricht University

Curated by ChEMBL
LigandPNGBDBM50376421(CHEMBL410426)
Affinity DataIC50:  8.95E+3nMAssay Description:Inhibition of factor 5a-mediated prothrombin activation in human plasma by prothrombinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin K-dependent protein C(Homo sapiens (Human))
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50193237(CHEMBL379430 | {(R)-1-[2-(4-carbamimidoyl-benzylca...)
Affinity DataIC50:  9.08E+3nMAssay Description:Inhibition of human aPCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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