Compile Data Set for Download or QSAR
maximum 50k data
Found 12 of kd data for polymerid = 239,1235,1261,5406,5454,5547,6926,50002629,50005203
TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 group M subtyp...)
Boehringer Ingelheim (Canada)

LigandPNGBDBM93213(Benzimidazole Inhibitor, 6)
Affinity DataIC50:  350nM Kd:  500nMAssay Description:In vitro capsid assembly assay (CAA) was used in a HTS to identify potential inhibitors of capsid assembly. More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 group M subtyp...)
Boehringer Ingelheim (Canada)

LigandPNGBDBM93209(Benzimidazole Inhibitor, 2)
Affinity DataIC50:  1.20E+3nM Kd:  4.30E+3nMAssay Description:In vitro capsid assembly assay (CAA) was used in a HTS to identify potential inhibitors of capsid assembly. More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 group M subtyp...)
Boehringer Ingelheim (Canada)

LigandPNGBDBM93210(Benzimidazole Inhibitor, 3)
Affinity DataIC50:  1.40E+3nM Kd:  8.00E+3nMAssay Description:In vitro capsid assembly assay (CAA) was used in a HTS to identify potential inhibitors of capsid assembly. More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 group M subtyp...)
Boehringer Ingelheim (Canada)

LigandPNGBDBM93208(Benzimidazole Inhibitor, 1)
Affinity DataIC50:  6.10E+3nM Kd:  4.30E+4nMAssay Description:In vitro capsid assembly assay (CAA) was used in a HTS to identify potential inhibitors of capsid assembly. More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 group M subtyp...)
TBA

Curated by ChEMBL
LigandPNGBDBM50450015(Bms-955176 | GSK-3532795)
Affinity DataKd:  6.5nMAssay Description:Binding affinity to HIV1 gag polyprotein V370A mutant containing viral like particleMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 group M subtyp...)
TBA

Curated by ChEMBL
LigandPNGBDBM50450016(CHEMBL4163247)
Affinity DataKd:  49nMAssay Description:Binding affinity to HIV1 gag polyprotein V370A mutant containing viral like particleMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 group M subtyp...)
TBA

Curated by ChEMBL
LigandPNGBDBM50450015(Bms-955176 | GSK-3532795)
Affinity DataKd:  34nMAssay Description:Binding affinity to HIV1 gag polyprotein delta V370 mutant containing viral like particleMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 group M subtyp...)
TBA

Curated by ChEMBL
LigandPNGBDBM50450016(CHEMBL4163247)
Affinity DataKd:  15nMAssay Description:Binding affinity to HIV1 gag polyprotein V362I mutant containing viral like particleMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 group M subtyp...)
TBA

Curated by ChEMBL
LigandPNGBDBM50450015(Bms-955176 | GSK-3532795)
Affinity DataKd:  4.30nMAssay Description:Binding affinity to HIV1 gag polyprotein V362I mutant containing viral like particleMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 group M subtyp...)
TBA

Curated by ChEMBL
LigandPNGBDBM50450016(CHEMBL4163247)
Affinity DataKd:  259nMAssay Description:Binding affinity to HIV1 gag polyprotein delta V370 mutant containing viral like particleMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 group M subtyp...)
TBA

Curated by ChEMBL
LigandPNGBDBM231619(GSK5750)
Affinity DataKd:  387nMpH: 7.8Assay Description:In this case, 1 μM HIV-1 RT was added to 50 mM Tris-HCl (pH 7.8), 50 mM NaCl, 6 mM MgCl2, and varying concentrations of GSK5750 to form enzyme-i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 group M subtyp...)
TBA

Curated by ChEMBL
LigandPNGBDBM50450015(Bms-955176 | GSK-3532795)
Affinity DataKd:  98nMAssay Description:Binding affinity to HIV1 gag polyprotein A364V mutant containing viral like particleMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed